Urolithiasis Flashcards
What is the epidaemiology of stones?
Prevalence in general population = 2-3%
Lifetime risk in males 1:8
M:F = 3:1
Peaks:
- Men = 30
- Women = Bimodal at 35 and 50
Chance of stone recurrence is 50% within 10 years (with 10% within a year)
Give the different stone types
Calcium oxalate = 45%
Calcium oxalate + phosphate = 25%
“Triple phosphate” infective = 20%
Calcium phosphate = 3%
Uric acid = 5%
Cystine = 3%
What are the symptoms and signs of stones?
Renal pain (fixed in loin)
Ureteric colic (radiating to groin)
Dysuria / haematuria / testicular or vulval pain
Urinary infection
Loin tenderness
Pyrexia
What are the investigations for stones?
Not imaging
Blood tests - FBC, U+E, Creatinine
Calcium, Albumin, Urate
-Hypercalcaemia should be excluded
Parathormone
Urine analysis and culture
24 hr urine collections
What radiological investigations can you use in stones?
X-ray KUB
-Can show up to 90% of stones
Ultrasound
-May show hydronephrosis
IVU (intravenous urogram)
CT-KUB
- GOLD STANDARD
- Very sensitive
What are the indications for surgical treatment?
Obstruction
Recurrent gross haematuria
Recurrent pain and infection
Progressive loss of kidney function
Patient occupation
What are the techniques for surgical treatment of stones?
Open surgery (now rare)
Endoscopic surgery
ESWL
Open surgery has become far less common with the advent of PCNL and ESWL
What are the advantages and disadvantages of open stone surgery?
Advantage
-Single procedure with least recurrence rate
Disadvantages
- Large scar
- Long hospital stay
- General wound complications
What are the indications for open surgery?
Non functioning infected kidney with large stones necessitating nephrectomy
Cases which for technical reasons cannot be managed by PCNL or ESWL
What is a simple pyelolithotomy?
What is a simple radial nephrotomy?
Small incision made to renal pelvis to remove stone
Having to cut into actual kidney tissue to get to calyx stone
What are the indications for simple partial and total nephrectomy?
Non functioning kidney with large staghorn stones or elderly frail patients with complex stones and normal contralateral kidney.
How common is contralateral stone formation after a total nephrectomy?
Up to 30%
What does PCNL stand for?
Percutaneous Nephrolithotomy
What type of stone gives the characteristic staghorn stone appearance?
Triple phosphate
Staghorn calculi are the result of recurrent infection and are thus more commonly encountered in women
What are the specific indications for PCNL?
Large stone burden (risk of Steinstrasse)
Associated PUJ stenosis
Infundibular stricture
Calyceal diverticulum
Morbid obestity or skeletal deformity
ESWL resistant stones
e.g. Cystine
Lack of availability of ESWL