urogynae Flashcards
Types of incontinence - Stress incontinence presentation
Involuntary leakage Cough Laugh Lifting Exercise Movement
Types of incontinence - Detrusor overactivity/overactive bladder presentation
Urgency Urgency incontinence Frequency Nocturia Nocturnal enuresis ‘Key in the door’ ‘Handwash’ Intercourse
assessment of incontinence (4)
Frequency volume chart (FVC) - Voided volume, Frequency of urination etc
Urinalysis (MSU)
Residual urine measurement (RU)
Questionnaire (ePAQ)
electronic Personal Assessment Questionnaire - 4 domains
Urinary Pain Voiding Overactive bladder Stress incontinence Quality of life
Bowel IBS Constipation Evacuation Continence Quality of life
Vaginal Pain Capacity Prolapse Quality of life
Sexual Urinary Bowel Vaginal Dyspareunia Overall sex life
detrusor muscle innervation neurotransmitter receptors antagonists
Innervation - Sacral Parasympathetic
Neurotransmitter - Acetylcholine
Receptors - Muscarinic: M2 & M3
Antagonsists - Atropine (Oxybutynin, Tolterodine, Solifenacin, Trospium)
agents for detrusor muscle activity
Anticholinergics: Atropine-like agents (Antimuscarinics) M2 & M3 Receptor Antagonists
B3 adrenergic agonist - mirabegron
botulinum toxin
anticholinergics: Atropine-like agents (Antimuscarinics) M2 & M3 Receptor Antagonists
examples
SE
OXYBUTYNIN Tolterodine Propiverine Trospium Solifenacin
dry mouth, drowsy, constipation, tachycardia
mirabegron
Mechanism of Action
Beta-3 adrenergic receptor agonist
Relaxes smooth muscle detrusor
Increases bladder capacity
physio - pelvic floor exercises
Pelvic floor muscle contraction
Clamping / compression of urethra
Increased urethral pressure
Reduced leakage
lifestyle adaptations to incontinence
Weight loss
Smoking cessation
Reduced caffeine intake
Avoidance of straining and constipation