Urine Formation Flashcards
What is hydrostatic pressure?
This is the force a fluid exerts on the walls of its container/compartment
What is Oncotic pressure?
This is the force exerted by plasma proteins on the walls of the compartment in which they are contained
Normal human urine consists of _______% water
95
The process of urine formation is carried out in how many phases?
Three
The first phase of urine formation is _____________
Glomerular filtration
Glomerular filtration takes place in the _____________
Glomerulus
**More accurately in the Renal corpuscle (Glomerulus and Bowman’s capsule)
Glomerular filtration occurs across three layers which are _______________, ______________, and ________________
Endothelium of the glomerular blood vessels
Basement membrane preventing filtration of large proteins
Epithelium of Bowman’s capsule (Podocytes)
The endothelium of glomerular blood vessels possess fenestrations that restrict the passage of __________
Blood cells
What is Net filtration pressure?
This is expressed by pressures favouring filtration minus pressures opposing filtration.
Glomerular hydrostatic pressure - Bowman’s capsule hydrostatic pressure - Glomerular protein Oncotic pressure
What is the relationship between GFR and Net filtration pressure?
GFR= Kf × NFP
Where Kf is the filtration coefficient
The major part of selective reabsorption takes place in the ________________
Proximal convoluted tubule
Selective reabsorption is regulated by hormones _________________ and ______________
Vasopressin/Anti-diuretic hormone (ADH)
Aldosterone
