Urine abnormalities Flashcards
Raised protein (A:CR, P:CR)
The higher the proteinuria, more likely due to glomerular disease
Haematuria causes
Visible/(a/symptomatic) non-visible due to malignancy, calculi, IgA nephropathy, Alport, PKD, glomerulonephritis
Myoglobin in urine can trigger false +ve for blood
Haematuria management
Any haematuria in >40yr needs imaging, cystoscopy + urological assessment
Renal referral if: eGFR<60 Proteinuria HT FHx renal disease
A:CR normal values
<2.5mg/mmol in male
<3.5mg/mmol in female
> 30 considered proteinuria
P:CR normal values
<15mg/mmol
> 50 considered proteinuria
Glucosuria indicates
DM
Pregnancy
Sepsis
Proximal renal tubular pathology
Ketonuria indicates
Ketoacidosis
Starvation
Leucocyturia indicates
UTI
Vaginal discharge
Nitrites in urine indicate
UTI (enteric gram -ve organism)
Bilirubin in urine indicates
Haemolysis
Urobilinogen in urine indicates
Liver disease
Haemolysis
Normal Urine pH
4.5-9, acidic in meat diet
RBC in urine microscopy
> 2/mm^3 is abnormal
May indicate bleeding from glomerulus
WBC in urine microscopy
> 10/mm^3 is abnormal
May indicate UTI, glomerulonephritis, tubulointerstitial nephritis, renal transplant rejection, malignancy
Red cell casts in urine microscopy
Inflammatory process in glomerulus