Urinary System Flashcards
List components of Urinary System:
Kidneys, Ureters, Urinary Bladder, Urethra
Function of Kidneys:
- Regulate blood ionic composition 2. Regulate blood PH 3. Regulate blood volume 4. Regulate blood pressure 5. Maintain blood osmolarity 6. Regulate blood glucose 7. Exrete waste/foreign materials 8. Produce hormones: Calcitrol & Erthropoetin
List the waste products secreted by kidneys:
ammonia, urea, bilirubin, kreatin
Anatomically, describe location of kidneys:
retroperitoneal & attached to the posterior wall of abdomen
What is the layer of the kidney superficial to the renal pyramids but deep to the renal capsule called?
renal cortex (fascia)
Trace the path of urine through kidneys:
Papillary ducts - Minor calyx - major calyx - renal pelvis
What do we call the blood vessels that supply the kidneys?
renal arteries
Renal nerves are classified as what type?
vasomotor (open/close)
What are the functional units of the kidneys?
nephrons
What are the components of the renal corpuscle?
glomerus & glomerular capsule
Trace the path that a molecule of water (or blood) would take to pass through the kidney:
glomerus - glomerular capsule - proximal convoluted tubule - descending LOH - distal convoluted tubule - collecting duct - papillary duct
Which components of the nephrons are associated with the juxtaglomerular apparatus?
afferent arterioles & ascending Loop of Henle
A loss of _____% of a person’s kidney function may not result in clinically observable effects.
10
As a person grows, what happens to the number of nephrons in his/her kidneys?
stay the same
If one kidney is removed, the other nephrons in the other kidney will _______.
hypertrophy (enlarge)
What is the first step in urine production?
water and solutes move from glomerus to glomerular capsule
How do we calculate the rate of urinary excretions of any solute?
Rage of GF + rate of secretion - rate of absorption
What does teh filtration membrane of the kidney consist of?
glomerular endothelial cells, basal lamina, & slit of membranes between the pedicals of podocytes
Why is the volume of fluid filtered by the renal corpuscle much larger than the volume exiting other capillaries?
Large surface area of the glomular capillaries
Which substances/cells can ordinarily cross the filtration membrane?
Water and small solutes
Which substances/cells can not cross the filtration membrane?
any blood product: blood cells, plasma proteins, platelets
Which mechanisms control glomerular filtration (GFR)?
Renal autoregulation Neural control Hormonal control
What is the myogenic mechanism of renal autoregulation?
normalizes renal blood flow and off in response to blood pressure
What does the tubuloglomerular mechanism of renal autoregulation depend on?
from feedback of macula densa
What would be the effecdt of decreased angiotensin II levels with increased ANP levels on GFR?
increase GFR
Tubular reabsorption returns ____% of the water filtered from the glomerulus to the blood.
99
Which common blood-born molecule would not ordinarily be secreted from the blood and tubular cells into tubular fluid?
glucose