Urinary stones Flashcards
3rd MC urinary tract D/O
Urinary stones
Urinary stones pop?
M > F (2.5:1)
30-50s
Urolithiasis def
Stone formations anywhere in urinary tract
Nephrolithiasis def
Stones in kidneys
Ureterolithiasis
Stones in the ureters
Urinary calculi composition
Polycrystalline aggregates of crystalloid/organic matrix
Basic pathophysiology of stone formation
Result of urinary supersaturation of solutes
-low fluid intake, low UA volume = high solutes
Most stones are compsed of?
Calcium = radiopaque
Most important factors of stone development
High protein/salt intake
Inadequate hydration
Sedentary
Geographic factors of stone development
High humidity
INC temp
Genetic predisposition condition? 3
Homozygous Cystinuria
Auto rec D/O
INC cysteine excretion
Acidic urine contributes to
Uric acid or cystine stones
Alkaline urine contributes to
UTI - urease producing organisms
-proteus / klebsiella
=strucite stones
5 major stone types
- Calcium oxalate
- Calcium phosphate
- Cystine
- Struvite AKA staghorn calculi
(-Mg ammonium phosphate) - Uric acid
MC urinary stone
Calcium Oxalate Stones
Calcium Oxalate pH range
5.5-6.5
Increased risks of developing Calcium Oxalate
High sodium/protein
Dehydrated
Hypercalceuria
Low urine citrate
XR attenuation of Calcium Oxalate?
Radiopaque
Citrate interaction w/ calcium
- UA citrate binds calcium
- Decreases calcium
- Prevents calcium phosphate/oxalate stones
Acidic urinary citrate level is?
Decreased
Alkalosis urinary citrate level is?
Increased
Calcium phosphate pH level
> 7.5 pH alakaline urine
Calcium phosphate Increased RFs?
High sodium/protein
Dehydration
Hypercalcuria
Low urine citrate
Calcium phosphate XR attenuation?
Radiopaque
Struvite stones are composed of?
Mg-ammonium-phosphate
Struvite stone MC pop?
Women w/ recurrent UTIs w/ urease producing bacteria