Urinary Incontinence Flashcards

1
Q

What is the normal fluid intake amount?

A

Normal fluid intake: 1.5 - 3L (more than this is polydipsia)

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2
Q

What is the normal size of a ‘full’ bladder?

A

• Normal full bladder: 250ml - 400mL

Therefore go to the toilet 4-8 times a day

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3
Q

What happens to the bladder with age?

A

• As we get older, our bladder loses capacity to stretch and loses functional reserve
Urinating up to twice a night normal if 65+

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4
Q

What is a normal residual volume post micturition?

A

After urinating, should have

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5
Q

What are the RF of urinary incontinence?

A
• Female
• Impaired cognition (delirium and dementia)
• UTI
• Constipation
• Impaired mobility
• Diabetes
• Bladder outflow obstruction
• Obesity** major factor in stress incontinence
Neurological diseases
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6
Q

What are the DIAPPERS precipitants of incontinence in the frail and disabled elderly?

A
  • Delirium
  • Infection
  • Atrophic urethritis or vaginitis
  • Pharmaceuticals
  • Psychological disorders esp depression
  • Excessive urine output e.g. HF, hyperglycaemia
  • Restricted mobility
  • Stool impaction
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7
Q

What is the role of the frontal lobe in urination?

A

Frontal Lobe: micturition control centre is located in the frontal lobe. It sends inhibitory signals to the detrusor muscle to prevent bladder contraction until it is socially acceptable.

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8
Q

What is the role of the pons in urination?

A

Pons: pontine micturition centre (PMC) coordinates bladder and sphincter. Promotes voiding.

A full bladder leads to signals from the stretch receptors of the detrusor muscle sent to the pons, which then signals the brain.

The frontal lobe can inhibit this sudden desire until appropriate. The PMC is deactivated, and urinary is delayed.

Children - usually the brain takes over the control of the pons at age 3-4 years, which is why most children undergo toilet training at this age

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9
Q

What is the role of the spinal cord in urination?

A

• Sacral reflex centre is the primitive voiding centre and is responsible for bladder contractions

Infants: higher centre of voiding has not been developed therefore control of urination is controlled by sacral reflex centre (bladdder fills, excitatory for sacral cord, detrusor muscle contraction)

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10
Q

What happens to the control of urination in a patient with spinal cord injury?

A

Spinal cord injury - patient will have Sx of urinary f, urgency, urge incontinence but will be unable to empty bladder completely. This is due to the bladder and sphincter are both overactive and leads to detrusor sphincter dyssynergia with detrusor hyperreflexia (DSD-DH) - the pathway from the sacral cord, up the spinal and to the pons is severed therefore pons cannot coordinate sphincter and detrusor

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11
Q

What is the role of peripheral nerves - SNS hypogastric and PNS pelvic nerve in voiding?

A

SNS via hypogastric nerve (T10-L2): storage. It causes
1. Bladder to increase its capacity without increasing the detrusor resting pressure (accommodation)
2. Stimulates the internal urinary sphincter to remain tightly closed
3. Inhibits PNS stimulation (micturition reflex inhibited)
PNS via pelvic nerve (S2-4): voiding. It causes
1. Stimulate detrusor muscle to contract (Ach)
2. Suppresses SNS influence on internal urethral sphincter, therefore relaxing and opening it
Pudendal nerve is inhibited to cause the external sphincter to open

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12
Q

What is the role of the somatic pudendal nerve in voiding?

A

Somatic via pudendal nerve (S2-S4)
• Pudendal nerve regulates the voluntary actions of the external urinary sphincter and the pelvic diaphragm. Activation of the pudendal nerve causes contraction of the sphincter and contraction of the pelvic floor muscles
• Neurapraxia of the pudendal nerve during prolonged vaginal delivery can cause stress urinary incontinence
• Suprasacral-infrapontine spinal cord trauma can cause overstimulation of the pudendal nerve resulting in urinary retention

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13
Q

Px findings in urinary incontinence

A

• Abdominal – masses, percussible bladder
• Pelvic – evaluation of pelvic floor muscles, genital prolapse (cystourethrocele, utero-cervical or vaginal vault prolapse, enterocele or rectocoele), evidence of oestrogen deficiency, sign of stress incontinence, bimanual (presence of tenderness and masses)
• Digital rectal examination of prostate – size and any irregularity
• Neurological – cognitive function, perineal reflexes/sensation, and lower limb reflexes, etc * look especially for MS
• Cardiac, peripheral oedema, orthopaedic, postural blood pressure in elderly
• Valsalva patient- ask patient to sneeze, cough, lift something heavy and look for leakage
If suspecting stress incontinence, make sure it is not overflow incontinence by asking them to valsalva

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14
Q

General Hx Q for all incontinence pts

A

• DOOFS
• Frequency during day
• Frequency during night
• LUTS esp dysuria
• Haematuria
• Oral intake: water and diuretics - how much fluid are you drinking and what type of fluid ar eyou drinking?
• Medications: Li (effect on collecting duct), diuretics
• Habits: counter bladder training “just in case pee”
• What are your triggers for urination?
• Nocturia: what time do you go to bed? What time do you get up?
Must assess impact on life: sleeping during day (if nocturia), waking up partner

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15
Q

Hx Q for urge incontinence

A
• Urge: Can you defer? 
• Do you experience constipation? 
• Have you had Sx of obstruction before?
• Bladder Ca: haematuria, constitutional Sx
Irritative symptoms or hx of UTI
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16
Q

Hx Q for stress incontinence

A

Stress:
• Do you leak with sneezing, coughing or lifting
• If female: after childbirth? Type of delivery? How many children? How big were the babies? Were there any complications? Did you do pelvic floor exercise after? Have you had gyne surgery? Have you had a prolapse - when you cough or sneeze do you see anything coming out of vagina, or do you feel like you are sitting on an egg?
If male: have you had prostate surgery

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17
Q

Hx Q for overflow incontinence

A
Overflow
• Obstructive LUTS
- Ca prostate Hx? 
- Hx of diabetes (ANS failure)
- LMN disease?
18
Q

Hx Q for functional incontience

A

• Are you able to mobilise and reach the toilet?
• How far are you from the toilet?
• What is lighting like?
• Is the toilet clearly marked so they can find it in residential facility
Is it an unobstructed way to get to toilet?

19
Q

What are the key Ix for urinary incontinence?

A

• Bloods: rule out biochemical abnormality - high glucose, high Ca
• Ix medication: Li, diuretics
• MSU to rule out UTI, blood, proteinuria
• Bladder diary: 2 day frequency-volume chart
• Urge incontinence will be high F and low volume urine
Post-void residual volume – needs to be repeated if abnormal (want it to be less than 50mL for normal)

20
Q

What is urodynamics testing?

A

» Urodynamics (the measure of P within bladder and sphincter) and flow rate study: can measure P intra abdo and P intracycle. Video urodynamics possible to view bladder (if urge: then may see bladder contractions at small volume) therefore can diagnose detrusor overactivity. Can see urinary stress incontinence when they sneeze, cough. Can tell you if obstruction or atony if difficulty emptying bladder. Good for all types of assessements of incontinence. Everyone must have urodynamics before surgery.
• Catheter inserted in backside or bladder. Then can fill up with water (simulate Urine) and watch bladder P monitor. Then can assess contraction, leakage. Not often done on old people.
Main indication for urodynamics is surgery assessment or diagnostic dilemma that wants to be solved by patient and doctor

21
Q

Three most important investigations (according to geri)

A

Three most important

  1. MSU rule out UTI
  2. Ix: rule out biochem abnormality or drug cause
  3. Make sure not in urinary retention with bladder US
22
Q

How do we prevent urinary incontinence?

A

• Appropriate postures for urination and defaecation
• Avoidance of constipation, straining at stool
• Good general fitness and avoidance of obesity
• Avoid smoking; treat chronic cough
• Good bladder habits (eg avoid frequent “just in case” voiding and over-distension)
Optimal obstetric management

23
Q

What are the non - drug management options?

A
  • Instruction re appropriate toileting posture
  • Appropriate modification of existing medications
  • Treat other contributing factors: faecal impaction, urinary tract infection, constipation, acute pain, diabetes, obesity (lose weight!)
  • Optimise toilet access
  • Appropriate fluids and diet
  • Minimise active risk factors
  • Continence products-consider referral to continence nurse advisor
  • Consider pharmacological causes (see table below)
  • Use bladder diary for at least 3 days, recording number of incontnent episodes, amount of loss and the circumstances
24
Q

What are the complications of urinary incontinence?

A
• Fear of odour, actual leakage, avoidance of activities, loss of confidence, depression
• Carer burden
• Skin infection and breakdown
• Urinary infection
Falls
25
Q

What is urge incontinence?

A
  1. Strong urge to void or, 2. the inability to defer (cannot hold on, do you have to rush to the toilet?)

History: Increase F, small amount

26
Q

What are the causes of urge incontinence?

A

Detrusor overactivity (instability) due to:
• Idiopathic (more common in F) usually due to bad bladder habits
• Medications
• Bladder outflow obstruction causes secondary detrusor overactivity - prostatic (BPH), urethral stricture, genital prolapse, post-stress incontinence surgery in F
• Bladder stone
- Bladder Ca
• Constipation (urge and overflow)
• UTI
• Neurological disease: stroke, Parkinson’s disease, dementia, MS, spinal cause injury, normal pressure hydrocephalus. IT is like a UMN bladder (UMN lesion - hypertonic, hyperreflexia)

27
Q

How do we manage urge incontinence?

A

Detrusor Overactivity (Urge)
• Behavioural techniques- bladder training, toileting regimens, biofeedback
• Pelvic floor muscle exercises-consider referral to continence physiotherapist wherever possible
• Specific medication:
1. anticholinergics - oxybutynin (relax the bladder muscle and increase bladder capacity)
- Surgery: if able to identify the reversible factor
- Botox injection

28
Q

What are the adverse effects of anti cholinergics?

A
  1. Older people are more sensitive to anticholinergic drugs: dry mouth, blurred vision, constipation, urinary retention (anti SLUDGE: anti salivation, lacrimation, urination, diaphoresis, GI motility, emesis
  2. Anticholinergics can worsen overflow incontinence; avoid in men at risk of urinary retention i.e. significant bladder outlet obstruction
29
Q

What is stress incontinence?

A
  • Involuntary leakage on effort, exertion, laughing, sneezing or coughing (more common in F, but can occur in M after radical prostatectomy or TURP)
  • This is not due to bladder contraction, but due to the change in posture or intraabdominal pressure
30
Q

What is the cause of stress incontinence in F and M?

A
Females
	• Urethral or vaginal atrophy
	• Pelvic floor atrophy
	• Ligament atrophy
	• After vaginal birth
	• Post menopausal atrophy - friable of vaginal epithelium (usually due to oestrogen) 
Males
After prostate surgery
31
Q

What are the conservative management options for stress incontinence?

A
  • Conservative: Pelvic floor muscle exercises - consider referral to continence physiotherapist. Effective! Reduce incontinence by 50% if compliant and good technique (3x day, 10 tonic contraction for 3 months)
  • (May include electrostimulation and biofeedback techniques)
  • Minimise risk factors
  • Intravaginal devices
32
Q

What are the surgical management options for stress incontinence?

A

• Surgery
» Women - injectables, slings, suspensions
» Men - slings, artificial urinary sphincter

33
Q

What is overflow incontinence?

A
  • the involuntary loss of urine associated with an over-distended bladder.
  • Bladder is either atonic (weak bladder contraction) or severely obstructed (constipation or prostate)
  • Begins with urinary retention. Then continuous or intermittent leakage may occur

(Can’t empty bladder, but has to come out somehow or somewhere)

34
Q

What are the causes of overflow incontinence?

A

The post void residual volume is high due to:
○ Prostate: outlet obstruction (e.g. BPH) - must ask about LUTS, haematuria and systemic features for Ca prostate or,
○ NS - Poor detrusor contractility: diabetes (ANS failure), prolonged and severe bladder outflow obstruction, pelvic surgery, LMN disease
○ Vaginal delivery, pregnancy hormonal, pelvic trauma, surgery

35
Q

How do we manage overflow incontinence?

A

Main: cathetrisation in acute situation (supra pubic catheterisation is uncommon in Aus)

Mx if it is obstructed: catheter and remove obstruction
Mx if it is atonic: no treatment, only catheter

36
Q

What is detrusor-sphincter dyssynergia?

A

usually spinal trauma
- bladder contraction and sphincter relaxation are not coordinated. Can be caused by any lesion in CNS. Get urge, but sphincters shut.
- Beware of any high pressure bladder in spinal trauma patient! Retention and backflow can be so great, that it congests the kidneys and can lead to pyelonephritis
• Usually dual treatment with anticholinergics and catheters. Improve drainage - clean intermittent catheterisation, indwelling catheterisation (also important to treat co-incident detrusor overactivity as well)

37
Q

What is functional incontinence?

A

occurs in otherwise continent people who are unable to get to or use the toilet in time, or are unable to recognise the need to void

38
Q

What are the causes of functional incontinence?

A

• Impaired mobility or dexterity (due to arthritis or muscle weakness)
• Environmental barriers (bedrails)
• Dementia
• Indirect effects of medication affecting balance
- Cognition or mental alertness

39
Q

Define nocturia.

A

What: >30% of 24 hour UO, or > 2/night

40
Q

What are the main causes of nocturia?

A

○ Overactive bladder: Trial anticholinergic if not in urinary retention
○ Nocturnal Hypertension - increase return, put on anti HTN
○ Peripheral oedema (fluid overload) - redistribute and cause nocturia: diurese them and put on stockings
○ Lack of ADH: Rx DDAVP (synthetic ADH)
○ OSA can lead to nocturia due to reduction in ADH
○ Diabetes insipidus
- Obstruction e.g. BPH

41
Q

How do we manage nocturia?

A

• Diagnose the cause – small bladder, nocturnal polyuria, sleep disorder
• Nocturnal polyuria – limit nocturnal fluids, compression stockings, other
Elderly in hospital and residential care facilities
Careful attention to treatment and prevention of precipitants of incontinence

42
Q

What residual volumes would prompt you to catheterise apatient?

A

If young ( 200mL residual volume - worry.
All, catheter above 500mL.
Must investigate afterwards as well