URINALYSIS Flashcards
Renal Blood Flow
Afferent arteriole —> Glomerulus —> Efferent arteriole —> Peritubular capillaries —-> Vasa Recta —-> Renal vein
Which of the tubules is impermeable to water
Ascending Loop of Henle
Glucose will appear in the urine if:
Renal threshold for glucose is exceeded (160-180 mg/dL)
Renal tubular acidosis can be caused by the:
Inability to produce an acidic urine due to impaired production of ammonia
Clearance tests used to determine the glomerular filtration rate must measure substances that are:
Neither reabsorbed or secreted by the tubules
Osmolality is a measure of:
Dissolved particles, including ions
Which of the following parameters are measured during the course of concentration and dilution test to assess renal tubular function?
Osmolality and SG
Corrects renal blood flow by VASODILATION OF THE AFFERENT ARTERIOLES & CONSTRICTION OF THE EFFERENT ARTERIOLES
Angiotensin II
Parameters of Cockcroft - Gault Formula: For estimated GFR
BAGS
Body weight in kg
Age
Gender/ Sex
Serum creatinine
Modification of Diet in renal Disease (MDRD) Formula
RAGS
Race
Age
Gender
Serum creatinine
Normal creatinine clearance:
120 mL/min
Men: 107-139 mL/min
Women: 87 - 107 mL/min
Substances in Active Transport
GACS
Glucose, AA, Salts
Chloride
Sodium
Substances in Passive transport
WUS
Water - PCT, DoH, CT
Urea
Sodium
Greatest source of error in GF Clearance test
Improperly timed urine specimens
Single marker that denotes renal failure
Creatinine
MArker of renal tubular integrity
B2- MICROglobulin
How many mL of urine is needed in drug testing?
30-45 mL in 60 mL container capacity
Temperature of urine in drug testing? How long before you measure the urine in drug testing?
32.5 - 37.7 C
urine temp must be taken within 4 mins of collection
___ hours contact time for the bacteria to turn nitrate to nitrite
4
What tests would determine if the specimen is a urine
Urea and creatinine
A cloudy specimen received in the laboratory may have been preserved using:
Refrigeration
Boric acid - strasinger
For general screening, the most frequently collected specimen is:
Random urine
If a px fails to discard the first specimen when collecting a timed specimen, the:
Specimen must be RECOLLECTED and results will FALSELY DEC
Primary cause of unsatisfactory results in an unpreserved routine specimen not tested for 8 hours is:
Bacterial growth
After receiving a 24 hour urine for quanti total protein analysis, what should u do
Measure the total volume
Urine spx are thrown into biohazardous waste container: T or F
False
When should u measure urobilinogen determination
2pm - 4pm
Imparts an orange-brown color to urine that is not fresh
Urobilin
Urine of px with diabetes mellitus
Colorless - pale yellow
HIGH SG - due to glycosuria and polyuria
Normal range of urine volume
Normal: 600 to 2000 mL
average: 1200 to 1500 mL
Color of urine when there is phenol poisoning
Brown
Green - if oxidized to quinines
Transparent, no visible particulates
CLEAR
Few particulates, print easily seen through urine
Hazy
Many particulates, print blurred through urine
Cloudy
Print cannot be seen through urine
Turbid
Urine: May precipitate or clot
Milky
Possible cause of red urine in children
Fuscin and aniline dye
Substance in urine that may be colorless due to LEAD POISONING
Porphyrin
Hyposthenuria
<1.010
SG of normal urine
1.002 - 1.035
Isosthenuria
1.010 (SG of filtrate leaving the glomerulus)
indicates loss of renal concentrating and diluting ability
Hypersthenuria
> 1.010
Principle of reagent strip
pKa change of a polyelectrolyte
Normal pH of urine
pH: 5.0 - 6.0
Can be seen in acidic urine due to respiratory acidosis; lungs cannot exhale CO2
Emphysema
Reagent strip of urine:
Double Indicator System
Reagents in pH reagent strip:
Methyl red (acidic)
Bromthymol blue (alkaline)
Ammoniacal urine
Infection
Normal odor of urine
Faint aromatic odor/ distinct or fragrant smell
Fruity, sweet urine
Ketone (DM)
Rotting fish
Trimethylaminuria
Rancid butter
Tyrosyluria
Sweaty feet
Isovaleric acidemia
Mousy odor
phenylketonuria
cabbage odor
methionine malabsorption
Maple syrup odor
MSUD ( high leucine, isoleucine, valine in blood and urine)
Bleach
contamination
Odorless urine
Acute tubular necrosis
Cystinuria
Rotten egg odor
Hawkinsinuria
Swimming pool odor
Conc. of a normal urine specimen can be estimated by:
Color
A patient with uncontrolled DM will most likely have a urine that is
Pale w/ a high specific gravity
Makes up the matrix of our urinary cast
Tamm-Horsfall protein