Ureter, Urinary Bladder, and Kidney

Question 1

Question: What is low-grade papillary urothelial carcinoma with inverted growth pattern?

Answer choices:

A) A type of invasive urothelial carcinoma
B) A type of urothelial carcinoma with a high risk of recurrence
C) A type of urothelial carcinoma that lacks an invasive appearance and does not invade into the muscularis propria
D) A type of urothelial carcinoma that has irregular nests and shows variation in cell size

Answer 1

C) A type of urothelial carcinoma that lacks an invasive appearance and does not invade into the muscularis propria.

Explanation: Low-grade papillary urothelial carcinoma with inverted growth pattern is a variant of urothelial carcinoma that is characterized by a lack of invasive appearance and an absence of invasion into the muscularis propria. It has rounded nests that are fairly uniform in size and usually crowded. It is important to distinguish this variant from the large nested variant of urothelial carcinoma, which has a more aggressive clinical behavior.