Upper GI Conditions Flashcards
GORD defn:
acid from the stomach flows
backwards
through the lower oesophageal sphincter into the oesophagus
Oesophagus has what lining?
stomach has?
squamous epithelium
columnar
Dyspepsia defn?
indigestion
2WW cancer referral?
Dysphagia at any age
> 55
weight loss
upper abdo pain
reflux
low haemoglobin
Endoscopy
camera through the mouth down to oesophagus
stomach
duodenum
Haitus hernias?
herniation of stomach up through diaphragm
4 types of hernia
type 1 sliding
type 2 rolling
3: combo
4: large opening with additional abdominal organs netering thoraxnf
famotidine
histamine h2 receptor antagonist
Surgery for reflux
laparoscopic fundoplication
H pylori
gram negative aerobic
flagella
produces ammonia hydroxide neutralising acid
toxins
metaplasia
change in cell type
so in barretts
squamous > columnar
dysplasia
abnormal cell type
Zollinger–Ellison Syndrome
duodenal / pancreatic tumour
= GASTRIN
= stimulates acid secretion in the stomach
gastrinomas are associated with MEN1