Upper GI bleed Flashcards

1
Q

What is upper gastrointestinal bleeding and where can it occur?

A

Upper gastrointestinal bleeding refers to bleeding from the oesophagus, stomach, or duodenum. It is a common medical emergency.

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2
Q

What are the key causes of upper gastrointestinal bleeding?

A
  • Peptic ulcers (most common cause)
  • Mallory-Weiss tear (tear of oesophageal mucosa)
  • Oesophageal varices (due to portal hypertension from liver cirrhosis)
  • Stomach cancers

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3
Q

What are the common symptoms of upper gastrointestinal bleeding?

A
  • Haematemesis (vomiting blood)
  • Coffee ground vomit (vomiting digested blood resembling coffee grounds)
  • Melaena (black, tarry stools from digested blood)
  • Haemodynamic instability may occur with significant blood loss, causing low blood pressure, tachycardia, and signs of shock.

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4
Q

How do peptic ulcers present in upper GI bleeding?

A

Peptic ulcers often present with epigastric pain and dyspepsia. Patients may also be using NSAIDs.

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5
Q

How does a Mallory-Weiss tear present in upper GI bleeding?

A

Mallory-Weiss tears are associated with heavy retching or vomiting, which may result from binge drinking, gastroenteritis, or hyperemesis gravidarum (in early pregnancy).

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6
Q

How do oesophageal varices present in upper GI bleeding?

A

Oesophageal varices are associated with liver cirrhosis and portal hypertension, presenting with signs of these conditions such as ascites, jaundice, and caput medusae.

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7
Q

How does stomach cancer present in upper GI bleeding?

A
  • Weight loss
  • Epigastric pain
  • Treatment-resistant dyspepsia
  • Low haemoglobin (anaemia)
  • Raised platelet count

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8
Q

What is the Glasgow-Blatchford Bleeding Score used for?

A

The Glasgow-Blatchford Bleeding Score helps estimate the risk of upper GI bleeding at the initial presentation. A score above 0 indicates high risk. Consider early discharge for patients with a score of 0.

Factors considered in the score include haemoglobin, urea, blood pressure, heart rate, melaena, syncope, liver disease, and heart failure.

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9
Q

What is the Rockall Score used for?

A

The Rockall Score is used after endoscopy to estimate the risk of rebleeding and mortality. It considers age, features of shock, co-morbidities, cause of bleeding, and endoscopic findings.

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10
Q

What is the ABATED mnemonic for managing upper GI bleeding?

A
  • A – ABCDE approach to resuscitation
  • B – Blood tests
  • A – Access (2 x large bore cannulas)
  • T – Transfusions
  • E – Endoscopy (within 24 hours)
  • D – Drugs (stop anticoagulants and NSAIDs)

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11
Q

What blood tests are important in the management of upper gastrointestinal bleeding?

A
  • Haemoglobin (Full Blood Count, FBC)
  • Urea (U&Es)
  • Coagulation profile (INR and platelet count)
  • Liver function tests (LFTs)
  • Crossmatch 2 units of blood

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12
Q

What guidelines are followed for blood transfusions in upper GI bleeding?

A
  • Massive bleeding: Blood, platelets, and clotting factors (fresh frozen plasma)
  • Thrombocytopenia: Platelets are given if platelet count is below 50 in active bleeding
  • Warfarin patients: Prothrombin complex concentrate for active bleeding

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13
Q

What additional treatments are needed if oesophageal varices are suspected?

A
  • Terlipressin
  • Broad-spectrum antibiotics
  • Endoscopy: Required to diagnose and treat the bleeding source (e.g., variceal band ligation for bleeding varices).

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14
Q

What role does endoscopy play in managing upper GI bleeding?

A

Endoscopy (OGD) helps diagnose and treat the bleeding source. Non-variceal bleeding can be treated with clips or thermal coagulation, while variceal bleeding requires band ligation.

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15
Q

What do the NICE guidelines say about proton pump inhibitors (PPIs) in upper GI bleeding?

A

The NICE guidelines (2016) recommend not using proton pump inhibitors (PPIs) until after endoscopy in patients with non-variceal upper GI bleeding.

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