Universal Flu Vaccine Flashcards
Antigenetic shift
Sudden changes of the surface antigens of a virus leading to very different recognition sites
Immunisation
Introduction of a dead or deactivated form of a virus to encourage the production of antibodies by the immune system to protect against actual infection
Hemaglutinin
A flu virus glycoprotein that binds to the host cell
Neuraminidase
An enzyme which helps the virus to breach cell walls
Antigenetic drift
Small changes in the gene of a virus that happen over time as the virus replicates, creating viruses that are slightly different to each other
Team 1
Applied mutations that realigned the subunits of the stem at the top, this allowed for a functional structure for the vaccine
Team 2
Pulled the subunits of the protein together by binding a bacteria-derived mani particle to the stem