Unit3 - Part 2

Question 1

Spliceosome

Answer 1

A large complex of proteins and RNA molecules that removes introns from pre-mRNA.

Question 2

Self-splicing

Answer 2

The ability of some RNA molecules to catalyze their own splicing without the need for additional proteins.

Question 3

Transesterification

Answer 3

A chemical reaction that involves the exchange of an ester group between two molecules. In splicing, it involves the breaking and forming of phosphodiester bonds.

Question 4

Branchpoint

Answer 4

A specific nucleotide sequence within an intron that is essential for the splicing reaction.

Question 5

snRNA (small nuclear RNA)

Answer 5

A class of small RNA molecules that form part of the spliceosome and play a crucial role in splicing.

Question 6

snRNP (small nuclear ribonucleoprotein)

Answer 6

A complex of snRNA and proteins that functions as a unit in the spliceosome.

Question 7

Intron lariat

Answer 7

A loop-shaped structure formed during splicing, containing the excised intron.

Question 8

U6

Answer 8

A specific snRNA that plays a critical role in catalysis during splicing.

Question 9

U2

Answer 9

A specific snRNA that recognizes the branchpoint sequence and helps to form the spliceosome.

Question 10

U1

Answer 10

A specific snRNA that recognizes the 5’ splice site of an intron.

Question 11

U5

Answer 11

A specific snRNA that interacts with both the 5’ and 3’ splice sites, bringing them together for splicing.