Unit Va-Nin Sterile Liquid Dosage Form(lec) Flashcards
one or more substances dissolved in a suitable
solvent
Solutions
Methods of Preparing Solutions
Simple Solution
• Application of Heat
• Addition of a Co-Solvent
• Rigorous Agitation
• Solution by Extraction
Liver solution
• Solution by Chemical reaction
MgCO3 + Citric Acid
Mg
most commonly used solvent
Water
7 types of water
Purified water
• WFI
• SWFI
• BWFI
• SWF Inhalation
• SWF Irrigation
• Sterile Purified Water
ph 5-7
PURIFIED WATER
Obtained by distillation
Purified water
Preparation of aqueous dosage forms EXCEPT
parenterals
Purified water FREE of pyrogens
WATER FOR INJECTION (WFI)
distillation or reverse osmosis
WATER FOR INJECTION (WFI)
WFI sterilized and
packaged into single-dose
containers
1 liter
Used for already sterilized
and packaged medication
STERILE WATER FOR INJECTION (SWFI)
contains antimicrobial agent
BACTERIOSTATIC WATER FOR INJECTION (BWFI)
Single or multi-dosecontainers
30 mL
NOT FOR NEONATES
BACTERIOSTATIC WATER FOR INJECTION (BWFI)
BACTERIOSTATIC WATER FOR INJECTION (BWFI) contains
Benzyl Alcohol
Distillation or reverse
osmosis / Not for parenterals
STERILE WATER FOR INHALATION
WFI sterilized and
suitably packaged
STERILE WATER FOR IRRIGATION
For irrigation use only,
Not for injection”
STERILE WATER FOR IRRIGATION
PW sterilized / Not for parenterals
STERILE PURIFIED WATER
TYPES OF SOLUTIONS
*Aqueous Solutions
*Non-aqueous Solutions
*Sweet solutions
clear liquid prescriptions, and homogeneous in nature
AQUEOUS SOLUTIONS
AQUEOUS SOLUTIONS example
Water
• Aromatic Waters
• Aqueous Acids
• Solutions
• Douches
• Enemas
• Gargles
• Mouthwashes
• Juices
both as a vehicle
Water
Universal Solvent
Water
medicated waters
AROMATIC WATERS
clear saturated aqueous solution of volatile oils
AROMATIC WATERS
Preparation of Aromatic Waters:
*Distillation
*Solution method
*Alternate Solution Method
Stronger Rose Water NF)
Distillation
Dissolve 2mg/mL v.o in 1L water; stay overnight and filter off excess oil
Solution Method
Triturate 2mg/2mL v.o with talc clarifying agent; dissolve in 1L water
and filter
Alternate Solution Method
diluted acids
AQUEOUS ACIDS
diluting
the corresponding
concentrated acids
with purified water
AQUEOUS ACIDS
Homogeneous mixture
SOLUTIONS
cavity for
cleansing
DOUCHES