Unit V: Drugs Affecting the Endocrine System - Hormones Flashcards
Hormone: Epinephrine
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Hormone: Epinephrine
Abbreviation: EPI
Hormone Type: amino-acid derived
Solubility: water
Released By: adrenal Gland (medulla)
Receptor: adrenergic receptor
Target Tissue: nearly all tissues
Effect: BP, glycogenolysis, lipolysis etc.
Hormone: Melatonin
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Hormone: Melatonin
Abbreviation: MT
Hormone Type: amino-acid derived
Solubility: water
Released By: pineal gland
Receptor: melatonin receptor
Target Tissue: CNS and peripheral tissue
Effect: circadian rhythm
Hormone: Norepinephrine
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Hormone: Norepinephrine
Abbreviation: NE
Hormone Type: amino-acid derived
Solubility: water
Released By: adrenal gland (medulla)
Receptor: noradrenergic receptor
Target Tissue: nearly all tissues
Effect: BP, glycogenolysis, lipolysis etc.
Hormone: Triiodothyronine
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Hormone: Triiodothyronine
Abbreviation: T3
Hormone Type: amino-acid derived
Solubility: lipid
Released By: thyroid gland (peripheral tissue)
Receptor: thyroid hormone receptor
Target Tissue: nearly all body cells
Effect: increase metabolism
Hormone: Thyroxine
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Hormone: Thyroxine
Abbreviation: T4
Hormone Type: amino-acid derived
Solubility: lipid
Released By: thyroid gland
Receptor: thyroid hormone receptor
Target Tissue: nearly all body cells
Effect: increase metabolism (similar effect to T3, but weaker; T4 is converted to T3 in target cells)
Hormone: Anti-Müllerian hormone
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Hormone: Anti-Müllerian hormone
Abbreviation: AMH
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Released By: testes (sertoli cells), follicles
Receptor: AMHR2
Target Tissue: testicular
Effect: Inhibit release of prolactin and TRH from anterior pituitary, regulate production of sex hormones, and also a critical to sex differentiation at a specific time during fetal development and in fertility, providing a guide to ovarian reserve
Hormone: Adrenocorticotropic/corticotropin hormone
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Hormone: Adrenocorticotropic/corticotropin hormone
Abbreviation: ACTH
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Released By: anterior pituitary
Receptor: ACTH (+cAMP)
Target Tissue: adrenal cortex
Effect: synthesis of corticosteroids (glucocorticoids and androgens) in adrenocortical cells e.g. cortisol
Hormone: Antidiuretic hormone
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Hormone: Antidiuretic hormone
Abbreviation: ADH
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Released By: posterior pituitary
Receptor: AVPRs, VACM-1
Target Tissue: kidney, anterior pituitary, peripheral vessels
Effect: retention of water in kidneys, moderate vasoconstriction, release of ACTH in anterior pituitary
Hormone: Calcitonin
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Hormone: Calcitonin
Abbreviation: CT
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Released By: thyroid gland
Receptor: CT receptor (+cAMP)
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Effect: Construct bone, reduce blood Ca2+
Hormone: Corticotropin-releasing hormone
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Hormone: Corticotropin-releasing hormone
Abbreviation: CRH
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Released By: hypothalamus
Receptor: CRF1 (+cAMP)
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Effect: Release ACTH from anterior pituitary
Hormone: FSH
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Abbreviation: FSH
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Hormone: GCG
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Hormone: GnRH
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Hormone: GHRH
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Hormone: hCG
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Abbreviation: hCG
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Hormone: HPL
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Abbreviation: HPL
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