Unit R-Endocrine Flashcards
Which statement best describes idiopathic hypopituitarism?
a. Growth is normal during the first 3 years of life.
b. Weight is usually more retarded than height.
c. Skeletal proportions are normal for age.
d. Most of these children have subnormal intelligence.
ANS: C
In children with idiopathic hypopituitarism, the skeletal proportions are normal. Growth is
within normal limits for the first year of life. Height is usually more delayed than weight.
Intelligence is not affected by hypopituitarism
A child with growth hormone (GH) deficiency is receiving GH therapy. What is the best time for the GH to be administered? a. At bedtime b. After meals c. Before meals d. On arising in the morning
ANS: A
Injections are best given at bedtime to more closely approximate the physiologic release of
GH. Before or after meals and on arising in the morning are times that do not mimic the
physiologic release of the hormone.
What is the priority nursing goal for a 14 year old diagnosed with Graves’ disease?
a. Relieving constipation
b. Allowing the adolescent to make decisions about whether or not to take medication
c. Verbalizing the importance of monitoring for medication side effects
d. Developing alternative educational goals
ANS: C
Children being treated with propylthiouracil or methimazole must be carefully monitored for
side effects of the drug. Because sore throat and fever accompany the grave complication of
leukopenia, these children should be seen by a health care practitioner if such symptoms
occur. Parents and children should be taught to recognize and report symptoms immediately.
The adolescent with Graves’ disease is not likely to be constipated. Adherence to the
medication schedule is important to ensure optimal health and wellness. Medications should
not be skipped and dose regimens should not be tapered by the child without consultation with
the child’s medical provider. The management of Graves’ disease does not interfere with
school attendance and does not require alternative educational plans.
Diabetes insipidus is a disorder of which organ?
a. Anterior pituitary
b. Posterior pituitary
c. Adrenal cortex
d. Adrenal medulla
ANS: B
The principal disorder of posterior pituitary hypofunction is diabetes insipidus. The anterior
pituitary produces hormones such as growth hormone, thyroid-stimulating hormone,
adrenocorticotropic hormone, gonadotropin, prolactin, and melanocyte-stimulating hormone.
The adrenal cortex produces aldosterone, sex hormones, and glucocorticoids. The adrenal
medulla produces catecholamines.
The nurse is caring for a child with suspected diabetes insipidus. Which clinical manifestation would be observable? a. Oliguria b. Glycosuria c. Nausea and vomiting d. Polydipsia
ANS: D
Excessive urination accompanied by insatiable thirst is the primary clinical manifestation of
diabetes. These symptoms may be so severe that the child does little other than drink and
urinate. Oliguria is decreased urine production and is not associated with diabetes insipidus.
Glycosuria is associated with diabetes mellitus. Nausea and vomiting are associated with
inappropriate antidiuretic hormone secretion.
What is a common clinical manifestation of juvenile hypothyroidism?
a. Insomnia
b. Diarrhea
c. Dry skin
d. Accelerated growth
ANS: C
Dry skin, mental decline, and myxedematous skin changes are associated with juvenile
hypothyroidism. Children with hypothyroidism are usually sleepy. Constipation is associated
with hypothyroidism. Decelerated growth is common in juvenile hypothyroidism.
The nurse is teaching the parents of a child who is receiving propylthiouracil for the treatment
of hyperthyroidism (Graves’ disease). Which statement made by the parent indicates a correct
understanding of the teaching?
a. “I would expect my child to gain weight while taking this medication.”
b. “I would expect my child to experience episodes of ear pain while taking this
medication.”
c. “If my child develops a sore throat and fever, I should contact the physician
immediately.”
d. “If my child develops the stomach flu, my child will need to be hospitalized.”
ANS: C
Children being treated with propylthiouracil must be carefully monitored for the side effects
of the drug. Parents must be alerted that sore throat and fever accompany the grave
complication of leukopenia. These symptoms should be immediately reported. Weight gain,
episodes of ear pain, and stomach flu are not usually associated with leukopenia.
A child diagnosed with hypoparathyroidism is receiving vitamin D therapy. The parents
should be advised to watch for which sign of vitamin D toxicity?
a. Headache and seizures
b. Physical restlessness and voracious appetite without weight gain
c. Weakness and lassitude
d. Anorexia and insomnia
ANS: C
Vitamin D toxicity can be a serious consequence of therapy. Parents are advised to watch for
signs including weakness, fatigue, lassitude, headache, nausea, vomiting, and diarrhea. Renal
impairment is manifested through polyuria, polydipsia, and nocturia. Headaches may be a sign
of vitamin D toxicity, but seizures are not. Physical restlessness and a voracious appetite with
weight loss are manifestations of hyperthyroidism. Anorexia and insomnia are not
characteristic of vitamin D toxicity.
Glucocorticoids, mineralocorticoids, and sex steroids are secreted by which organ?
a. Thyroid gland
b. Parathyroid glands
c. Adrenal cortex
d. Anterior pituitary
ANS: C
These hormones are secreted by the adrenal cortex. The thyroid gland produces thyroid
hormone and thyrocalcitonin. The parathyroid glands produce parathyroid hormone. The
anterior pituitary produces hormones such as growth hormone, thyroid-stimulating hormone,
adrenocorticotropic hormone, gonadotropin, prolactin, and melanocyte-stimulating hormone.
Chronic adrenocortical insufficiency is also referred to as what?
a. Graves’ disease
b. Addison’s disease
c. Cushing’s syndrome
d. Hashimoto’s disease
ANS: B
Addison’s disease is chronic adrenocortical insufficiency. Graves’ and Hashimoto’s diseases
involve the thyroid gland. Cushing’s syndrome is a result of excessive circulation of free
cortisol.
What is the characteristic of the immune-mediated type 1 diabetes mellitus?
a. Ketoacidosis is infrequent
b. Onset is gradual
c. Age at onset is usually younger than 18 years
d. Oral agents are often effective for treatment
ANS: C
The immune-mediated type 1 diabetes mellitus typically has its onset in children or young
adults. Peak incidence is between the ages of 10 and 15 years. Infrequent ketoacidosis,
gradual onset, and treatment with oral agents are more consistent with type 2 diabetes.
Which symptom is considered a cardinal sign of diabetes mellitus?
a. Nausea
b. Seizures
c. Impaired vision
d. Frequent urination
ANS: D
Hallmarks of diabetes mellitus are glycosuria, polyuria, and polydipsia. Nausea and seizures
are not clinical manifestations of diabetes mellitus. Impaired vision is a long-term
complication of the disease.
Type 1 diabetes mellitus is suspected in an adolescent. Which clinical manifestation may be present? a. Moist skin b. Weight gain c. Fluid overload d. Poor wound healing
ANS: D
Poor wound healing is often an early sign of type 1 diabetes mellitus. Dry skin, weight loss,
and dehydration are clinical manifestations of type 1 diabetes mellitus.
A parent asks the nurse why self-monitoring of blood glucose is being recommended for her
child with diabetes. The nurse should base the explanation on what information?
a. It is a less expensive method of testing.
b. It is not as accurate as laboratory testing.
c. Children need to learn to manage their diabetes.
d. The parents are better able to manage the disease.
ANS: C
Blood glucose self-management has improved diabetes management and can be used
successfully by children from the time of diagnosis. Insulin dosages can be adjusted based on
blood sugar results. Blood glucose monitoring is more expensive but provides improved
management. It is as accurate as equivalent testing done in laboratories. The ability to self-test
allows the child to balance diet, exercise, and insulin. The parents are partners in the process,
but the child should be taught how to manage the disease.
The parents of a child who has just been diagnosed with type 1 diabetes ask about exercise.
The nurse should provide the parents with what information to address the child’s safety
needs?
a. Exercise will increase blood glucose.
b. Exercise should be restricted.
c. Extra snacks are needed before exercise.
d. Extra insulin is required during exercise.
ANS: C
Exercise lowers blood glucose levels, which can be compensated for by extra snacks. Exercise
is encouraged and not restricted unless indicated by other health conditions. Extra insulin is
contraindicated because exercise decreases blood glucose levels.
A child eats some sugar cubes after experiencing symptoms of hypoglycemia. This
rapid-releasing sugar should be followed by:
a. saturated and unsaturated fat.
b. fruit juice.
c. several glasses of water.
d. complex carbohydrate and protein.
ANS: D
Symptoms of hypoglycemia are treated with a rapid-releasing sugar source followed by a
complex carbohydrate and protein. Saturated and unsaturated fat, fruit juice, and several
glasses of water do not provide the child with complex carbohydrate and protein necessary to
stabilize the blood sugar.
What are the manifestations of hypoglycemia?
a. Lethargy
b. Thirst
c. Nausea and vomiting
d. Shaky feeling and dizziness
ANS: D
Some of the clinical manifestations of hypoglycemia include shaky feelings; dizziness;
difficulty concentrating, speaking, focusing, and coordinating; sweating; and pallor. Lethargy,
thirst, and nausea and vomiting are manifestations of hyperglycemia
The nurse is caring for an 11-year-old boy who has recently been diagnosed with diabetes.
What should be included in the teaching plan for daily injections?
a. The parents do not need to learn the procedure.
b. He is old enough to give most of his own injections.
c. Self-injections will be possible when he is closer to adolescence.
d. He can learn about self-injections when he is able to reach all injection sites.
ANS: B
School-age children are able to give their own injections. Parents should participate in
learning and giving the insulin injections. He is already old enough to administer his own
insulin. The child is able to use thighs, abdomen, part of the hip, and arm. Assistance can be
obtained if other sites are used.
The nurse is discussing various sites used for insulin injections with a child and her family.
Which site usually has the fastest rate of absorption?
a. Arm
b. Leg
c. Buttock
d. Abdomen
ANS: D
The abdomen has the fastest rate of absorption but the shortest duration. The arm has a fast
rate of absorption but short duration. The leg has a slow rate of absorption but a long duration.
The buttock has the slowest rate of absorption and the longest duration.
What should a nurse advise the parents of a child with type 1 diabetes mellitus who is not
eating as a result of a minor illness?
a. Give the child half his regular morning dose of insulin.
b. Substitute simple carbohydrates or calorie-containing liquids for solid foods.
c. Give the child plenty of unsweetened, clear liquids to prevent dehydration.
d. Take the child directly to the emergency department
ANS: B
A sick-day diet of simple carbohydrates or calorie-containing liquids will maintain normal
serum glucose levels and decrease the risk of hypoglycemia. The child should receive his
regular dose of insulin even if he does not have an appetite. If the child is not eating as usual,
he needs calories to prevent hypoglycemia. During periods of minor illness, the child with
type 1 diabetes mellitus can be managed safely at home.
Which laboratory finding confirms that a child with type 1 diabetes is experiencing diabetic ketoacidosis? a. No urinary ketones b. Low arterial pH c. Elevated serum carbon dioxide d. Elevated serum phosphorus
ANS: B
Severe insulin deficiency produces metabolic acidosis, which is indicated by a low arterial
pH. Urinary ketones, often in large amounts, are present when a child is in diabetic
ketoacidosis. Serum carbon dioxide is decreased in diabetic ketoacidosis. Serum phosphorus
is decreased in diabetic ketoacidosis.
A child diagnosed with hypopituitarism is being started on growth hormone (GH) therapy.
Nursing considerations should be based on which information?
a. Treatment is most successful if it is started during adolescence.
b. Treatment is considered successful if children attain full stature by adulthood.
c. Replacement therapy requires daily subcutaneous injections.
d. Replacement therapy will be required throughout the child’s lifetime.
ANS: C
Additional support is required for children who require hormone replacement therapy, such as
preparation for daily subcutaneous injections and education for self-management during the
school-age years. Young children, obese children, and those who are severely GH deficient
have the best response to therapy. When therapy is successful, children can attain their actual
or near-final adult height at a slower rate than their peers. Replacement therapy is not needed
after attaining final height. They are no longer GH deficient.
The nurse is admitting a toddler with the diagnosis of juvenile hypothyroidism. Which is a
common clinical manifestation of this disorder?
a. Insomnia
b. Diarrhea
c. Dry skin
d. Accelerated growth
ANS: C
Dry skin, mental decline, and myxedematous skin changes are associated with juvenile
hypothyroidism. Children with hypothyroidism are usually sleepy. Constipation is associated
with hypothyroidism. Decelerated growth is common in juvenile hypothyroidism.
Which clinical manifestation may occur in the child who is prescribed methimazole for the
treatment of hyperthyroidism (Graves’ disease)?
a. Seizures
b. Enlargement of all lymph glands
c. Pancreatitis or cholecystitis
d. Sore throat or fever
ANS: D
Children being treated with propylthiouracil or methimazole must be carefully monitored for
side effects of the drug. Because sore throat and fever accompany the grave complication of
leukopenia, these children should be seen by a health care practitioner if such symptoms
occur. Neither seizures, cholecystitis nor pancreatitis are associated with the administration of
methimazole. Enlargement of the salivary and cervical lymph glands may occur.
The parent of a child diagnosed with diabetes mellitus asks the nurse when urine testing will
be necessary. The nurse should explain that urine testing is necessary for which reason?
a. Glucose is needed before administration of insulin.
b. Glucose is needed 4 times a day.
c. Glycosylated hemoglobin is required.
d. Ketonuria is suspected.
ANS: D
Urine testing is still performed to detect evidence of ketonuria. Urine testing for glucose is no
longer indicated for medication administration because of the poor correlation between blood
glucose levels and glycosuria. Glycosylated hemoglobin analysis is performed on a blood
sample.
To help the adolescent deal with diabetes, the nurse must consider which characteristic of
adolescence?
a. Desire to be unique
b. Preoccupation with the future
c. Need to be perfect and similar to peers
d. Need to make peers aware of the seriousness of hypoglycemic reactions
ANS: C
Adolescence is a time when the individual wants to be perfect and similar to peers. Having
diabetes makes adolescents different from their peers. Adolescents do not wish to be unique;
they desire to fit in with the peer group and are usually not future oriented. Forcing peer
awareness of the seriousness of hypoglycemic reactions would further alienate the adolescent
with diabetes since the peer group would likely focus on the differences.
The nurse is implementing care for a school-age child admitted to the pediatric intensive care
experiencing symptomology associated with diabetic ketoacidosis (DKA). Which prescribed
intervention should the nurse implement first?
a. Begin 0.9% saline solution intravenously as prescribed.
b. Administer regular insulin intravenously as prescribed.
c. Place child on a cardiac monitor.
d. Place child on a pulse oximetry monitor.
ANS: A
All patients with DKA experience dehydration (10% of total body weight in severe
ketoacidosis) because of the osmotic diuresis, accompanied by depletion of electrolytes
(sodium, potassium, chloride, phosphate, and magnesium). The initial hydrating solution is
0.9% saline solution. Insulin therapy should be started after the initial rehydration bolus
because serum glucose levels fall rapidly after volume expansion. The child should be placed
on the cardiac and pulse oximetry monitors after the rehydrating solution has been initiated.
A nurse is reviewing the laboratory results on a school-age child diagnosed with
hypoparathyroidism. Which results are consistent with this condition?
a. Decreased serum phosphorus
b. Decreased serum calcium
c. Increased serum glucose
d. Decreased serum cortisol
ANS: B
The diagnosis of hypoparathyroidism is made on the basis of clinical manifestations
associated with decreased serum calcium and increased serum phosphorus. Decreased serum
phosphorus would be seen in hyperparathyroidism, elevated glucose in diabetes, and
decreased serum cortisol in adrenocortical insufficiency (Addison’s disease).
A nurse is planning care for a school-age child diagnosed with type 1 diabetes. Which insulin
preparations are either rapid or short acting? (Select all that apply.)
a. Novolin N
b. Lantus
c. NovoLog
d. Novolin R
ANS: C, D
Rapid-acting insulin (e.g., NovoLog) reaches the blood within 15 minutes after injection. The
insulin peaks 30 to 90 minutes later and may last as long as 5 hours. Short-acting (regular)
insulin (e.g., Novolin R) usually reaches the blood within 30 minutes after injection. The
insulin peaks 2 to 4 hours later and stays in the blood for about 4 to 8 hours.
Intermediate-acting insulins (e.g., Novolin N) reach the blood 2 to 6 hours after injection. The
insulins peak 4 to 14 hours later and stay in the blood for about 14 to 20 hours. Long-acting
insulin (e.g., Lantus) takes 6 to 14 hours to start working. It has no peak or a very small peak
10 to 16 hours after injection. The insulin stays in the blood between 20 and 24 hours.
The clinic nurse is reviewing hemoglobin A1c levels on several children with type 1 diabetes.
Hemoglobin A1c levels of less than _____% are a goal for children with type 1 diabetes.
Record your answer as a whole number.
ANS:
7
The measurement of glycosylated hemoglobin (hemoglobin A1c) levels is a satisfactory
method for assessing control of type 1 diabetes. As red blood cells circulate in the
bloodstream, glucose molecules gradually attach to the hemoglobin A molecules and remain
there for the lifetime of the red blood cell, approximately 120 days. The attachment is not
reversible; therefore, this glycosylated hemoglobin reflects the average blood glucose levels
over the previous 2 to 3 months. The test is a satisfactory method for assessing control,
detecting incorrect testing, monitoring the effectiveness of changes in treatment, defining
patients’ goals, and detecting nonadherence. Hemoglobin A1c levels of less than 7% are a
well-established goal at most care centers.
The nurse assesses an older client. What age-related physiologic changes would the nurse expect? a. Heat intolerance b. Rheumatoid arthritis c. Dehydration d. Increased appetite
ANS: C
As people age, the many of the endocrine glands decrease hormone production, including a
decrease in antidiuretic hormone production. This change, in addition to less body fluid being
present as one ages, can cause dehydration. Older adults usually have cold intolerance and a
decrease in appetite. Rheumatoid arthritis is not an age-related change; osteoarthritis causes
primarily by aging.
A client is scheduled to have a glycosylated hemoglobin (A1C) drawn and asks the nurse why
she has to have it. How would the nurse respond?
a. “It measures your average blood glucose level for the past 3 months.”
b. “It determines what type of anemia you may have.”
c. “It measures the amount of liver glycogen you have.”
d. “It determines you have some type of leukemia or other blood cancer.”
ANS: A
A1C measures the average blood glucose level to determine if the client is a diabetic or how
controlled a diabetic client is.
The nurse assesses a client who is scheduled to have a laboratory test to determine if the
client’s adrenal glands are hypoactive. What type of testing would the client likely have?
a. Catecholamine testing
b. Suppression testing
c. Bone marrow testing
d. Provocative testing
ANS: D
Provocative testing is done to determine if an endocrine gland is capable of producing its
normal level of hormone(s), especially when a client is suspected of having a hypoactive
endocrine gland.
A nurse assesses a client who is prescribed a medication that stimulates beta1 receptors.
Which assessment finding would indicate that the medication is effective?
a. Heart rate of 92 beats/min
b. Respiratory rate of 18 breaths/min
c. Oxygenation saturation of 92%
d. Blood pressure of 144/69 mm Hg
ANS: A
Stimulation of beta1 receptor sites in the heart has positive chronotropic and inotropic actions.
The nurse expects an increase in heart rate and increased cardiac output. The other vital signs
are within normal limits and do not indicate any response to the medication.
A nurse collaborates with assistive personnel (AP) to provide care for a client who is
prescribed a 24-hour urine specimen collection. Which statement would the nurse include
when teaching the AP about this activity?
a. “Note the time of the client’s first void and collect urine for 24 hours.”
b. “Add the preservative to the container at the end of the test.”
c. “Start the collection by saving the first urine of the morning.”
d. “It is okay if one urine sample during the 24 hours is not collected.”
ANS: A
The collection of a 24-hour urine specimen is often delegated to AP. The nurse must ensure
that the AP understands the proper process for collecting the urine. The 24-hour urine
collection specimen is started after the client’s first urination. The first urine specimen is
discarded because there is no way to know how long it has been in the bladder, but the time of
the client’s first void is noted. The client adds all urine voided after that first discarded
specimen during the next 24 hours. When the 24-hour mark is reached, the client voids one
last time and adds this specimen to the collection. The preservative, if used, must be added to
the container at the beginning of the collection. All urine samples need to be collected for the
test results to be accurate.
A nurse assesses a female client who presents with hirsutism. Which question would the nurse
ask when assessing this client?
a. “How do you plan to pay for your treatments?”
b. “How do you feel about yourself?”
c. “What medications are you prescribed?”
d. “What are you doing to prevent this from happening?”
ANS: B
Hirsutism, or excessive hair growth on the face and body, can result from endocrine disorders.
This may cause a disruption in body image, especially for female clients. The nurse would
inquire into the client’s body image and self-perception. Asking about the client’s financial
status or current medications does not address the client’s immediate problem. The client is
not doing anything to herself to cause the problem, nor can the client prevent it from
happening.
A nurse is caring for a patient who has excessive catecholamine release. Which assessment
finding would the nurse correlate with this condition?
a. Decreased blood pressure
b. Increased pulse
c. Decreased respiratory rate
d. Increased urine output
ANS: B
Catecholamines are responsible for the fight-or-flight stress response. Activation of the
sympathetic nervous system can be correlated with tachycardia. Catecholamines do not
decrease blood pressure or respiratory rate, nor do they increase urine output.
The nurse is teaching assistive personnel (AP) about hormones that are produced by the
adrenal glands. Which hormone has the primary responsibility of maintaining fluid volume
and electrolyte composition?
a. Sodium
b. Magnesium
c. Aldosterone
d. Renin
ANS: C
Aldosterone is a hormone secreted by the adrenal cortex that causes water and sodium
absorption to maintain body fluid volume. Renin is secreted by the kidney to trigger
angiotensinogen converting angiotensin I to angiotensin II to help control blood pressure.
Magnesium and sodium are electrolytes and not hormones.
The nurse reviews the function of thyroid gland hormones. What is the primary function of calcitonin? a. Sodium and potassium balance b. Magnesium balance c. Norepinephrine balance d. Calcium and phosphorus balance
ANS: D
Calcitonin is the primary body hormone that is secreted from the thyroid gland and is
responsible for maintaining calcium and phosphorus balance.