Unit One Exam

Question 1

Who submits the Animal Welfare Assurance of Compliance that the animal research program meets all relevant regulations and standards?

Answer 1

Institutional Official

Question 2

T/F: The Registry is a mandatory program that documents

professional development.

Answer 2

False

Question 3

Which is NOT a required skill for ALAT’s?

A: Feeding animals
B: Changing animal bedding
C: Determining the sex of animals
D: Diagnosing diseases in animals

Answer 3

D: Diagnosing diseases in animals.

Question 4

Which of the following provides the most valuable information about the research animals’ health and environment?

A: Accurate, up-to-date records
B: A well-composed protocol
C: The laboratory animal science mission statement
D: Standard operating procedures

Answer 4

A: Accurate, up-to-date records.

Question 5

What helps to ensure that the data collected are not influenced by factors related to animal management?

Answer 5

Consistency

Question 6

Which of the following warm-blooded vertebrates are NOT regulated by the Animal Welfare Act?

A: Guinea pigs
B: Wild mice
C: Purpose-bred rats
D: Rabbits

Answer 6

C: Purpose-bred rats

Question 7

What nonprofit organization accredits laboratory animal research programs?

Answer 7

AAALAC International (Association for Assessment and Accreditation of Laboratory Animal Care)

Question 8

What guidelines must an animal facility follow when research animals are euthanized at the end of a study?

Answer 8

AVMA Guidelines for the Euthanasia of Animals

Question 9

Beyond food, water, shelter, and healthcare requirements, to comply the Animal Welfare Act, what must be provided to dogs in a laboratory animal research facility?

Answer 9

Opportunities for exercise.

Question 10

To whom is Animal Welfare Assurance of Compliance Statement submitted?

Answer 10

Office of Laboratory Animal Welfare (OLAW)

Question 11

What are the 3 R’s?

Answer 11

Replacement, refinement, reduction

Question 12

Who administers the Animal Welfare Regulations?

Answer 12

APHIS (Animal and Plant Health Inspection) of the USDA (United States Department of Agriculture)

Question 13

How often must IACUC perform inspections of the facility?

Answer 13

Every 6 months

Question 14

Who has the authority to sign the PHS Assurance?

Answer 14

The Institutional Official

Question 15

Who reviews all animal use protocols at the institution before studies using animals can begin?

Answer 15

IACUC

Question 16

How often does APHIS inspect the animal research facility?

Answer 16

At least once a year

Question 17

Which regulations apply to animal and non-animal research and safety studies funded or reviewed by the Food and Drug Administration and the Environmental Protection Agency?

Answer 17

Good Laboratory Practices

Question 18

What is the role of a Quality Assurance Unit?

Answer 18

To ensure compliance with the GLP’s (Good laboratory Practices)

Question 19

Which type of SOP addresses procedures specific to each study?

Answer 19

Procedural

Question 20

The appropriate use of analgesics in postsurgical animals applies to which principle of the 3 R’s?

Answer 20

Refinement

Question 21

Records of USDA inspections are available to the public under a provision of which federal law?

Answer 21

Freedom of Information Act

Question 22

Who develops the disaster plan?

Answer 22

Senior management and safety officials

Question 23

______ involves the development of methods for uniquely recognizing humans based upon physical features?

Answer 23

Biometrics

Question 24

Where should the contact list be posted?

Answer 24

In common areas that have heavy traffic.

Question 25

Why is it especially important that a background check is done for potential new employees of an animal research facility?

Answer 25

To avoid hiring anyone opposed to the use of animals in research.

Question 26

Which federal agency enforces the rules or standards related to workplace safety?

Answer 26

OSHA (Occupational Safety and Health Administration)

Question 27

At what noise level is considered a hazard to your hearing?

Answer 27

85 Decibels

Question 28

What does an eyewash station use to clean the eye?

Answer 28

Clean water under low pressure

Question 29

What is radioactivity?

Answer 29

The loss of energy by the emission of particles

Question 30

Which type of hazard causes musculoskeletal injuries?

Answer 30

Ergonomic

Question 31

What is the term of a disease that can be transmitted between animals and humans?

Answer 31

Zoonosis

Question 32

What provides information on the toxicity of chemicals?

Answer 32

SDS (Safety Data Sheet)

Question 33

Whose standards specifically address the storage and handling of radioactive materials in the facility?

Answer 33

NRC (Nuclear Regulatory Commission)

Question 34

Which aspect of the annual health screen is especially important for animal care staff working with primates?

Answer 34

Tuberculin skin test

Question 35

What type of injury can be prevented by taking frequent short breaks to rest and stretch the body?

Answer 35

Repetitive motion

Question 36

What are three of the most common types of cage washers used in today's facilities?

Answer 36

Tunnel washer, rack washer, cabinet washer

Question 37

Which of the following is NOT a method used to test for residual microorganisms following decontamination? A: Inoculating RODAC plates B PCR testing of plenum and air filter dust C: ATP measurement swabs D: Spore strips

Answer 37

D Spore strips

Question 38

List two reasons that automatic watering systems are often used to provide drinking water for laboratory animals.

Answer 38

They reduce the incidence of ergonomic injuries. They eliminate labor in washing and sterilizing water bottles, They provide a filtration system for the water.

Question 39

What features of a biological safety cabinet protect the animal inside.

Answer 39

The HEPA filtration system. | High Efficiency Particulate Air

Question 40

How is waste from tissue digesters disposed of?

Answer 40

Flushing down a sanitary sewer

Question 41

What precautions must be taken when autoclaving a liquid substance in a bottle?

Answer 41

Liquid containers should not be tightly sealed or completely filled because the liquid will expand as the temperature rises.

Question 42

What three characteristics determine the required time, pressure, and temperature of an autoclave?

Answer 42

The type, size and contamination level of the material being sterilized.

Question 43

List the three methods that are used to check the effectiveness of an autoclave cycle, and give an example of each:

Answer 43

Mechanical: Pressure gauges Chemical: Autoclave tape Biological: Spore strips

Question 44

Sterilizes instruments, equipment, and glass items using superheated steam and pressure

Answer 44

Autoclave

Question 45

Buns material such as animal tissues and trash

Answer 45

Incinerator

Question 46

Uses a sliding beam and weighing platform to determine weights

Answer 46

Balance

Question 47

Protects the user from exposure to pathogenic microorganisms

Answer 47

Class III BSC (Bio-safety Cabinet)

Question 48

Protects the user from chemical fumes

Answer 48

Fume hood

Question 49

What two features of a cage dumping station help protect the technician during cage changing?

Answer 49

The air-circulating fan | The HEPA filter

Question 50

What chemicals are often added to animals' drinking water to reduce bacterial contamination?

Answer 50

Acid and chlorine

Question 51

What type of cage washer is best used for cleaning larger pieces of equipment such as bulk carts and cage racks?

Answer 51

Rack washer

Question 52

What is super heated steam?

Answer 52

Steam that is maintained at a greater temperature than 212 degrees F. because it is maintained at a higher pressure.

Question 53

What type of micro-isolation cage is not mechanically ventilated? How is this type of cage venilated?

Answer 53

Static Micro-isolation cage: It has a filtered lid that allows passive air exchange into and out of the cage.

Question 54

Why is feed offered in more than one location for group-housed animals?

Answer 54

Because dominant animals may hoard feed.

Question 55

What health problem in guinea pigs can be caused by wire mesh flooring?

Answer 55

Pododermatitis

Question 56

List the two species the most commonly found in aquatic cages in the laboratory setting

Answer 56

African clawed Frog | Zebra fish

Question 57

Four types of plastics used to manufacture small animal caging systems, and withstand frequent autoclaving.

Answer 57

Polyethylene Polycarbonate Polysulfone Polyphenylsulfone

Question 58

What scenario would a disposable cage not be preferable?

Answer 58

For studies involving nonhuman primates

Question 59

What are the five parameters that determine the necessary size of a primary enclosure?

Answer 59

Weight, vertical height and length of animal, enrichment needs, experimental requirements, exercise requirements

Question 60

Metabolism cages are most commonly used with which of the following types of animals: A: Ruminants B: Rodents C: Swine D: Amphibians

Answer 60

B: Rodents

Question 61

What are the two types of research studies that use biocontainment caging systems for the animals?

Answer 61

Infectious | Toxicity

Question 62

If animals are infected with pathogens that are regulated by the CDC or the USDA, what special feature must their cages have?

Answer 62

A locking mechanism

Question 63

What type of caging is not recommended by the Guide for rats and mice?

Answer 63

Wire bottom cages

Question 64

Squeeze cages are typically used to hold what type of species of animals?

Answer 64

Nonhuman primates

Question 65

Nestling materials, toys, foraging devices, and food treats are examples of which type of enrichment?

Answer 65

Environmental enrichment

Question 66

Suspended caging systems are commonly used for which species?

Answer 66

Rabbits

Question 67

What type of caging is the term "jump box" used to describe?

Answer 67

Transfer cage