Unit One Flashcards
Extrinsic regulation of heart is innervation of the heart via
Autonomic nervous system
Why does HR at 180 stop increasing CO
Not having enough time for diastole, or need ventricles to fill
SA block
Flow (volume per unit time) represented by what
Q
The purkinje fibers lead from the
AV node, through the AV bundle through the left and right bundle branches then throughout the ventricular muscle
During diastole, aortic pressure falls due to
Elastic recoil of the aorta to 80 mmHg
Normal cardiac output is
5 L/min
Equation for stroke volume
End diastolic volume - end systolic volume
Carbon dioxide retention causes
Acidosis leading to confusion, come, arrhythmia, muscle weakness, GI disturbances
3rd degree AV blocks look like what
AV node creates own pace, SA node communications with AV node is not happening
Semilunar valves close when
Aortic/ pulmonic pressure greater than ventricular pressure
What are the three places within the systemic circuit that has serial blood supply
Liver, kidney and anterior pituitary
What is intrinsic regulation of the heart
Frank starlings mechanism
What can cause left axis deviation
Short stock build, obesity, LV hypertrophy and left bundle branch block
Relaxation of heart requires what
Pumping Ca2+ back into SR and out of the cell
Individually leads 1, 2, or 3 should be was QRS voltage
.5 - 2 mV
Cardiac muscle cells exhibit what two properties
Automaticity and rhythmicity
Right atrial stretch increase heart rate by
10 - 20%
AV node located where
Posterior right atrium
What is stroke volume
Amount of blood ventricle ejects after one contraction
Equation for ejection fraction
Strok volume/ end diastolic volume x 100
What occurs during phase 2
V gated slow Ca2+ channels open and decrease in K+ permeability also occurs
Lead one positive lead goes where
Left shoulder/ wrist
Aka of incisura
Dicrotic notch
Decreased voltage of QRS is caused by
Damaged heart muscle
What is S1 heart sound
First heart sound, closure of AV valves, “lib”, beginning of systole
Biphasic is what type of quantity
Vector
How is there a greater force of contraction on a cellular level in heart
Cardiac muscles sarcomeres are short and resist stretch, increase in length increases number of functional cross bridges between actin and myosin therefore creating greater force of contraction
What is einthoven’s triangle
Group of leads that form a triangle
1st AV block
Is the systemic circuit parallel or series
Parallel
V3 goes where
Between V2 and V4
What are the standard bipolar limb leads
Lead 1,2,3
What is a blood conditioner organ
Any organ that changes the composition of the blood for the benefit of the rest of the body
Tachycardia caused by
Fever, certain toxins, SNS activity
What can cause LV hypertrophy
Hypertension, aortic valve stenosis, aortic valve regurgitation
What occurs during phase 3
V gated Ca2+ channels close and V gated K+ channels open
QRS complex represents
Ventricular depolarization
What are some organs that are important but not blood conditioners
Brain, muscle and heart
Contractility is a modification of
Strength independent of loading changes
What is Monophasic
Only show amplitude of voltage changes as recorded at a point in a cell
2nd degree AV block looks like
Dropped beat, ventricles don’t have electrical activity, skipped beats
What are the three components of the aortic pressure curve
During systole, incisura, and during diastole
Why can you have multiple negative electrodes but have one positive
Positive electrode gives direction it is heading toward
V1 goes where
4 ICS to the right of sternum
Positive lead of aVL
Left wrist
The systemic circuit goes from where to where
Left ventricle, body, right atrium
Function of systemic circuit
Supplies many organs, trunk, head and limbs in parallel circulation
Can demands be met by just diffusion from the outside of the body
No, diffusion is too slow over large distances
Parasympathetic does what to heart
Decreases heart rate, weakly decreases force of contraction
Sinus arrhythmia can occur when heart rate increases with
Deep inspiration
Negative lead for aVL
Right wrist and right ankle
Current injury is what
Acute damaged heart muscle (MI) does not repolarize normally and therefore becomes a source of current
V2 goes where
4 ICS to the left of sternum
Are there any measuring forces in EKG
No just electricity
What is end diastolic volume
Amount of blood volume in ventricle at end of diastole
How many phases of the heart
Phase 0 through 4
what is the S3 heart sound
Due to filling of ventricles in mid diastole
Purpose of hexaxial reference system
Used to determine the vector of depolarization through the heart
The cardiac cycle components relating to pressure changes are recorded from the
Left atrium and ventricle
Premature contractions can occur in what part of heart
Atrial and ventricular
What is extreme axis
-90 to -180 degrees
The SA node connects to the
Atrial muscle and internodal fibers
V5 should go where
5 ICS, left anterior axillary line
What are the two forms of work the heart does
External work and kinetic energy of blood flow
Conduction system coordinates what
Timing of atrial and ventricular contractions
Can you hear S4
No, only recorded using phonocardiograms
Frank starlings law of heart says venous return equals what
Cardiac output
Lead two negative lead goes where
Right shoulder/ wrist
How long for O2 to diffuse 1 cm
14 hours
AV valves open when
Atrial pressure greater than ventricular pressure
Conduction blocks can be due to
Some part of heart sustained damage
Advantage of parallel circuit
If something is blocked then there are other ways around to have area receive blood, simultaneous blood supply
How does the venous system work with pressure and bringing blood to heart
Pressure still builds up but not greater than arterial pressure and veins contain valves
QRS usually last for how long
.04 to .11 sec
How much of the blood in the atria moves to the ventricles before atrial systole
80%
What occurs to ventricle during late systole
Reduced ejection
What occurs to ventricle during middle diastole
Diastasis, reduced inflow
What occurs during S4 heart sound
Due to atrial systole
What causes right axis deviation
Tall, long waist, lean build, RV hypertrophy, right bundle branch block
What occurs to ventricle during late diastole
Last 20% of blood comes in, atrial systole
The pulmonary circuit goes from where to where
Right ventricle, lungs to left atrium
AVR should show what type of deflection
Negative due to going from left to right
What are the parts of the left heart
Left atrium, bicuspid/ mitral valve, left ventricle and aortic valve, pulmonary veins
Sympathetic does what to heart
Increases heart rate, increases force of contraction
What is the equation for resistance
8Ln/(pi)r^4
Semilunar valves open when
Ventricular pressure greater than aortic/ pulmonic pressure
Equation for cardiac output
Stroke volume x heart rate
Location of SA node
Superior posterolateral right atrium
During exercise, how to increase cardiac output
Increase heart rate or increase stroke volume or both
What is the negative electrode in the precordial chest leads
Machine is used as reference point
Increased voltage of QRS is caused by what
Hypertrophy
Ventricle diastole has how many phases
Three, early, middle and late
What is ejection fraction
Amount of blood percent squeezed out at end of contraction
What occurs during isovolumic relaxation
Pressure in ventricle decreases, valve can now close, diastole
P R interval goes from what to what
SA node to AV node
When do AV valve close
Ventricular pressure greater than atrial pressure
Lead one negative lead goes where
Right shoulder/ wrist
Phase 2 aka
Plateau
What are not propagated through the fibrous septum
Action potentials
What is S2 heart sound
Closure of the semilunar valve, “dub”, transition into diastole
What is the main determinant of resistance
Blood vessel radius especially in arteriole
What are the characteristics of brain, muscle and heart not being blood conditioners
Blood flow is regulated to be at or just above metabolic need, loss of blood flow to these organs has more dramatic effect
Phase 3 aka
Repolarization
Main purpose of the cardiovascular system
Provide a sufficiently fast mechanism of delivery and removal of gasses, nutrients, and wastes by blood flow
Is sinus arrhythmia a normal variant
Yes
What explains why the T wave is positive (lead 2)
Due to the pattern starting at apex then goes to base
Contractility is what type of state
Ionotropic state
Function of internodal tract
Spread AP to AV node, spread AP into both atria, help to spread AP throughout cells
atrial fibrillation
What is einthovens law
2 = 1 + 3, in regards to the amplitude of the R wave
Function of left heart
Receives blood from lungs and pumps blood to body
What must the heart do in order for flow to occur
Arterial pressure greater than venous pressure
V6 should go where
5 ICS, left mid axillary line
What is the external work the heart does
Move blood from veins to arteries (most of the work done)
Why is the blood vessel radius in arterioles the most important
Radius is regulated the most here
Contractility includes effects of
autonomic nervous system and hormones
What is an electrode
Physical wired from machine to skin
EKG notices what
Deflection from zero lines due to depolarizations and repolarizations