unit 8 reading Flashcards
threshold for oliguria
< 400 mL/24 hr
nephrotic syndrome
excretion of > 3.5 g of protein (albumin) due to glomerular injury
nephritic syndrome
hematuria and red blood cell casts
- less sesvere proteinuria than nephrotic
pathophysiological changes from CKD
- gradual creatinine elevation
- GFR declines
- sodium lost in urine
- potassium is retained
- acidosis develops
- erthropoietin production diminished
cause of neurogenic bladder
neural lesion that interrupts innervation on bladder
- upper motor neuron lesions result in overractive bladder function and loss of bladder coordination
- sacral lesions result in underactive, hypotonic or atonic bladder function
most common type of kidney stone
calcium oxalate
what is hydronephrosis
dilation of the renal pelvix proximal to a blockage
- the increased pressure from urine backup decreases GFR
cause of tubulointerstitial fibrosis
chronic hydronephrosis (obstructive uropathy) leads to pressure-induced ischemia and accumulation of scar tissue
how long does it take for tubular damage to affect kidney function
7 to 28 days
what happens in postobstructive diuresis
after obstruction is relieved, the body attempts to correct fluid and electrolyte imbalances through rapid excretion of up to 10 L/day
renal colic
pain related to dilation and psams of smooth muscle related to ureteral obstruction