Unit 6 - Iron Metabolism & Storage

Question 1

• Element: Fe
• Atomic number: 26
• May ba 2+ or 3+
• Redox change: required for metabolism
• Body iron content: 3-4 g

Answer 1

Iron

Question 2

Ferrous (2+) ions is a _ (reduced, oxidized), gained an electron.

Answer 2

reduced

Question 3

Ferric (3+) ions is a _ (reduced, oxidized), lost an electron.

Answer 3

oxidized

Question 4

Iron compartments:

Hb iron

Answer 4

70%

Question 5

Iron compartments:

Storage iron
1. Ferritin
2. Hemosiderin

Answer 5

25%

Question 6

Iron compartments:

Myoglobin iron

Answer 6

5%

Question 7

Iron compartments:

Other sources:
1. Peroxidase, catalase
2. Cytochromes
3. Fiboflavin enzymes
4. Transferrin

Answer 7

<1%

Question 8

Iron compartments:

Serum

Answer 8

0.1%

Question 9

Iron functions:

Oxygen carriers

Answer 9

Hemoglobin

Question 10

Iron functions:

Oxygen storage

Answer 10

Myoglobin

Question 11

Iron functions:

Energy production

Answer 11

• Cytochromes (oxidative phosphorylation)
• Krebs cycle enzyme

Question 12

Iron functions:

Other functions of iron

Answer 12

Liver detoxification (cytochrome p450)

Question 13

What are the Iron Toxicity in Iron? (4)

Answer 13

1. Damage tissues
2. Catalyzes the conversion of hydrogen peroxide to free-radical ions
3. Free-radicals attacks cellular membranes, proteins, DNA
4. Iron excess possibly related to cancers, cardiac toxicity

Question 14

Iron deficiency may due to: (2)

Answer 14

1. Excessive bleeding
2. Inadequate intake