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Biol 200 > Unit 6-Cytoskeleton > Flashcards

Unit 6-Cytoskeleton Flashcards

1
Q

What is the non-polar filament

A

Intermediate filaments

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1
Q

What does polarity in filaments allow for

A

Motor protein movement

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2
Q

Which way does Kinesin travel

A

to + end

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3
Q

Which way does Dynein travel

A

to - end

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4
Q

Which end of MT grows faster in vitro

A

+ end

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5
Q

Which end of MT does not grow in vivo and why

A
  • end, attached to centrosome/MTOC
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6
Q

How do beta tubular control dynamic instability

A

They can hydrolyze GTP -> GDP causing MT disassembly

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7
Q

What is GTP cap

A

Area that is not experiencing GTP hydrolization

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8
Q

What motor protein is responsible for Golgi placement

A

Dynein

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9
Q

What motor protein is responsible for vesicle transport

A

Kinesin

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10
Q

What motor protein is responsible for ER placement

A

Kinesin

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11
Q

What motor protein is responsible for lysosomal transport

A

Dynein

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12
Q

What is nucleation

A

Initial assembly

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13
Q

Taxol stabilizes MT filaments what does this mean?

A

MT filaments will not depolymerize

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14
Q

Colchicine binds with tubular dimers what does this do?

A

Prevents MT polymerization

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15
Q

Nocodazole binds with tubular dimers what does this do?

A

Prevents MT polymerization

16
Q

Phalloidin stabilizes actin filaments what does this mean?

A

Prevents depolymerization

17
Q

Cytochalasin caps PLUS END of actin filaments what does this mean?

A

Actin filaments will depolymerize at minus end?

18
Q

Latrunculin binds to g-actin what does this do?

A

Prevents polymerization

19
Q

What does ARP 2/3 do?

A

provides a nucleation site for actin which leads to branching/ movement

20
Q

What way do most myosin go?

A

+ end

21
Q

What actin arrangement do cells have at leading edge of cell

A

Lamellipodium

22
Q

What is the consequence of no de-polymerization for actin

A

No movement because no trailing edge

23
Q

What is Critical Concentration?

A

Threshold at which there are enough reactants for the reaction to go forward

24
Q

What do intermediate filaments do?

A

Provide mechanical strength to cells

25
Q

What do microtubules do?

A

Determine cell shape and organelle placement

26
Q
A

Biol 200 (1 decks)

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