Unit 5 - Female Repro Disorders Flashcards
Malignant Breast Conditions Prevention
Exercise and breastfeeding
Malignant Breast Conditions Risk Factors
Gender: female Increased age: >60 Genetics: BRCA 1/2 Hormones: Contraceptive use, early period, late menopause, no pregnancies/no full term pregnancies, geriatric pregnancy, long term estrogen/progesterone use Hx of breast cancer Obesity Alcohol
Malignant Breast Conditions S/S
Lump Skin dimpling Change in skin color/texture Change in nipple appearance Clear/bloody d/c from nipple Atypical: redness, swelling, pain, warmth
Dx of breast cancer: Mammogram
Avg risk: q 1-2y at 40yo
High risk: HCP preference
Dx of breast cancer: Breast exams
q 3 y age 20-39
q y after age 40
Dx of breast cancer: MRI
Implants
Dense breast tissue
Dx of breast cancer: breast bx
Preferred method for dx
Needle or surgical
Dx of breast cancer: labs
Estrogen (ER) and progesterone receptor (PR) assays
Malignant breast conditions: protective factors
Maintain normal weight Physical activity Avoid/limit alcohol Breastfeeding for a year or longer Medications: Chemo prevention for high risk
Ducts carcinoma in situ (DCIS)
Cancer cells on milk ducts without spread into tissues
Best cure rate
Localized
Lobular carcinoma in situ (LCIS)
Marker with tissue changes that show increased risk for cancer
Invasive ductal cancer
Mist common and deadly
Spreads rapidly
Invasive
Invasive lobular breast cancer
About 10-15% of breast cancers dx
Breast cancer prognosis/tx
Depends on tumor size and lymph node involvement
TMN - tumor, metastasis, nodes
Breast cancer sx: lumpectomy
Removal of lump
Bx sentinel node
Breast cancer sx: total/simple mastectomy
Removal of breast, bx sentinel node
Breast cancer sx: modified radical mastectomy with sentinel node bx/lymph node dissection
Removal of breast and lymph nodes
Breast cancer sx: radical mastectomy
Removal of breast, lymph nodes, muscle