Unit 4: Uses of LA Flashcards
what are the used of LA
Topical
Local Infiltration
Peripheral N. Block
Intravenous
Epidural
Spinal
Tumescent Liposuction
the max amount of lidocaine plane is ____
300mg
the max amount of lidocaine with epi is ____
500
112.5 mgs of Bupivacaine with Epi and 250 mgs of Lidocaine with Epi were both given during a plastic surgery case.
What are the percentages of each local anesthetic based on the recommended maximum single dose in mgs?
you gave 50% of the max of epi and bup
which is 100% of the max
Where can you do topical anesthesia?
Applicable on the mucous membranes of the nose, mouth, tracheobronchial tree, esophagus, or GU tract.
cocaine is ___ ____ as a topical anesthetic than tetracaine and lidocaine
more effective
inhalation of lidocaine does not alter airway resistance
T or F
T
Procaine and Chloroprocaine are _____ as topical anesthetics
ineffective
EMLA is composed of ….
Lidocaine 2.5% and Prilocaine 2.5% = 5% LA
dose of EMLA is
Dose: 1 to 2 gms/ 10 cm2 area
EMLA
Readiness: ____ minutes OOA
45 min
2 hours: Skin grafting
10 minutes
Cautery of genital warts
Venipuncture, lumbar puncture
Arterial cannulation (Nitroglycerine)
Myringotomy
EMLA is contraindicated with _____ allergies
amide
EMLA can cause ___ because it contains propivicaine
methemoglobinemia
Epi is contraindicated in ____ anesthesia of end arteries
local infiltration
end arteries: ears, toes, nose, penis
Local infiltration is _____ placement of LA
extravascular
SubQ
peripheral NB is achieved by
LA injection into tissues surrounding individual peripheral nerves or nerve plexuses.
MOA of peripheral NB
MOA: diffusion from outer mantle to central core of nerve along a concentration gradient.
S/SX: proximal affected first and then distal.
@End: proximal comes back first & then distal.
*** Smallest sensory and ANS fibers first, and then larger motor and proprioceptive axons.
Smallest _____ and ANS fibers first, and then larger ___ and proprioceptive axons.
sensory; motor
onset of action of lidocaine and bupivacaine
OOA: Dependent on LA pK
Lidocaine: 3 minutes
Bupivacaine: 15 minutes
duration of a LA depends on the ____
dose
the “stop light sign” can be seen in what block?
interscalene
What is the Bier block?
IV injection of LA into an extremity isolated from the rest of the systemic circulation with a tourniquet
Sensation and muscle tone dependent on tourniquet
What drugs are used for the Bier block?
Ester or amide LA can be used
Mepivacaine > Lidocaine, but …
Most commonly used: Lidocaine
in the Bier block what cuff do you deflate first?
distal, then proximal
What is the sequence of neuraxial anesthesia
SNS
Sensory
Motor
(ANS first ) BP: will drop over 20mmHg
HR: Increase
(sensory 2nd)
assess with cold alcohol pad to see if sensory is effected
Motor is last. You then assess the movement of the extremity
SAB is an injection os LA in _____
subarachnoid area of spinal cord
With SAB youll have a ___ confirmation
CSF
act on preganglionic fibers
Sensory effect is on ___ level of denervation
SNS effect is __ spinal segments cephalad of sensory
Motor effect is___ spinal segments below sensory
Sensory effect is on same level of denervation
SNS effect is 2 spinal segments cephalad of sensory
Motor effect is 2 spinal segments below sensory
T1-T4 is the ___ accelerator
cardiac
If the assessed sensory level after SAB is at Thoracic 6 (Tip of Xiphoid Process), what are the:
SNS level
Motor level of the block?
T4
T8
Most common drugs for SAB are:
Most common: Tetracaine, Lidocaine, Bupivacaine, Ropivacaine, and Levobupivacaine
SAB Dosage is according to:
____ of patient (volume of subarachnoid space)
Height:
Segmental level of anesthesia desired
Duration of anesthesia desired
Pt is 5’5, how many mls will you give
1.5ml
most common epidural anesthesia drug is ____
lidocaine
onset of epidurals is
15-30 min
slow diffusion
Epidural anesthesia can cross the placental barrier with the epidural and affect the fetus for ___ to ___ hr
24-48hr
Bupivacaine or Lidocaine will cross the transplacental barrier more?
lidocaine will because it is more rapid in onset
what is the difference with epidural vs SAB?
No differential zone of SNS, sensory, and motor blockade
Large doses required for the differential
Tumescent Liposuction uses SQ infiltration of ____ volumes
large
Tumescent Liposuction
LA Plasma Peak is ___ to ____ hours s/p injection
12-14
Tumescent Liposuction
Recommended dose:
Regional Anesthesia Lidocaine with Epi: ___ mg/kg
7
Highly diluted Lidocaine with Epi Tumescent: 35 to 55 mg/kg
Theory: 1 gm of SQ can absorb up to 1 mg of Lidocaine
(aka: Tissue Buffering System)
Local anesthesia with ____ aspirates & prolonged postoperative analgesia
bloodless