Unit 3 Test Flashcards
Sympathetic nerve activity
- Increase in HR
- Increase in SV
- Increase in CO
- Increase in flow for venous return
- Constrict arterioles, decrease conductance
Parasympathetic nerve activity
- Decrease in HR
Metaboreceptors
- Sense changes in metabolites (H+ and Pi)
- If metabolites increase, it increases
- Activates the medulla
Feedback control
- Metaboreceptors
- Baroreceptors
Feedforward control
- Mechanoreceptors
- Motor outflow/drive
- Both activate the medulla
Baroreceptor
- Sense changes in MAP
- Increase with increasing blood pressure
- Inhibits the medulla
Medulla
- Activates SNA
- Inhibits PNA
What happens to arterioles with increasing intensity?
Dilation
Blood flow and metabolism
- Blood flow increases in proportion to
metabolism
Theory 1: The vasodilator hypothesis
- As metabolism increases so do the bi-
products
(vasodilators) such as extracellular K+,
adenosine, CO2, Lactate and H+ - These cause vasodilation which causes
increase in blood flow
Theory 2: O2/ nutrient lack theory
- Decreased O2 availability causes there to be
less ATP in the arterioles causing smooth
muscle relaxation - This causes increased dilation and
conductance = Increased blood flow
Sub-maximal exercise in hypoxic air
- DO2 can be restored due to a large enough
compensatory increase in dilation and then
blood flow
Peak exercise in hypoxic air
- DO2 can not be fully compensated for an increase
in blood flow
Ways to increase VO2 max
- Increase blood flow, increase CO, increase
DO2 - Increase O2 extraction by increasing CaO2
- Increase capillary density
The impact of hypoxia on a-vO2 difference
- Decreases due to decreased CaO2
Ventilation
- Increases PaO2
- Inhibits PaCO2
PaO2
- Higher the delivery of oxygen the greater the
capillary PaO2 - The higher Phi for flow of oxygen to muscles
PaCO2
H+
Feedback control of ventilation
Feedforward control of ventilation
Key characteristics of substrate use during exercise
- Increasing intensity increases carbohydrate
(glycogen) metabolism - Increasing duration increases fatty acid
metabolism - Training increases fatty acid metabolism at a
given exercise intensity
Increased intensity and increased carbohydrate metabolism
- Increasing exercise duration = increased reliance
on fat metabolism - Decreases reliance on carbohydrate metabolism
Carbohydrate metabolism
- Within training, there is an increased reliance on
fat - There is a decreased reliance on carbohydrate
metabolism during prolonged exercise
Increased duration and training and increased fatty acid metabolism
- With training or extended exercise duration there
is increased availability of fats - Increase inflow from fatty acid metabolism and
aerobic ATP production