Unit 3 - section 2 Flashcards

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1
Q

What is a pilot study?

A

Study carried out to test the experimental procedures before commencing the study

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2
Q

What is usually done as a result of carrying out a pilot study?

A

Evaluation and modification of experimental procedures

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3
Q

What are the 5 aspects of experimental design that can be assessed/developed during a pilot study?

A

Effectiveness of technique and gives experimenter experience with procedures
Range of values of independent variable
Identification and control if confounding variables
Number of repeats and replications required
Suitable timescale for procedures

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4
Q

What is a confounding variable?

A

Any variables that may affect the dependent variable other than the independent variable

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5
Q

Why is it important to monitor a confounding variable if it cannot be kept constant?

A

So it’s affect can be considered during results

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6
Q

How can the effects of a confounding variable that is difficult to keep constant be minimised?

A

By blocking experimental and control groups so that an even distribution from each block are exposed to each independent variable

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7
Q

What are discrete and continuous variables?

A

Discrete variables - data that can only take on certain individual values eg cell number in Petri dish
Continuous variables - data that can take on any value in a certain range eg temperature

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8
Q

What are the 3 types of data that can be gathered?

A

Quantitative - information that can be measured in numbers
Qualitative - information that involves descriptions. It can be observed but cannot actually be measured
Ranked - data is revalued and given a rank instead of the actual measurement/observation

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9
Q

What can the type of variable and data gathered affect when presenting or analysing findings?

A

The way the data is presented
Discrete - in bar graph
Continuous - in line graph

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10
Q

What is an independent variable?

A

Factor being changed in an investigation

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11
Q

What is an experimental treatment group compared with?

A

A control group

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12
Q

What is a dependent variable?

A

Factor that changes as a result of the independent variable changing

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13
Q

How many variables are altered in simple experimental design?

A

I variable

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14
Q

How many variables are altered in multifactorial experimental design?

A

More than 1 variable

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15
Q

What is an advantage and a disadvantage of simple and multifactorial experimental designs?

A

Advantage simple - usually in vitro so easier to control variables than in the field
Disadvantage simple - findings may not be accepted in the wider scientific community
Advantage multifactorial - lots of data can be obtained which can show complex interactions
Disadvantage multifactorial - usually in vivo so difficult to control

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16
Q

What do vivo and vitro mean?

A

Vivo - natural habitat

Vitro - in a lab

17
Q

Are vivo or vitro experiments more complex?

A

Vivo are more complex

18
Q

What is an observational study?

A

Uses groups that already exist so there is not a true independent variable as the observer is not causing the change

19
Q

What are the limitations of observational study?

A

It can determine correlation but not causation

20
Q

What is a control and what is its purpose in an experiment?

A

Controls are not exposed to the experimental conditions and are hard to compare to the treatment groups to identify false positives

21
Q

What is a positive control?

A

Group that is not exposed to the experimental treatment but to another treatment that is known to produce the expected effect

22
Q

What is a negative control?

A

Group that is not exposed to the experimental treatment or any other treatment that is expected to have an effect

23
Q

What is a representative sample and when would it be used?

A

Small sample of the whole population that is used when it is not practical to sample every single individual in a population

24
Q

What determines an appropriate sample size?

A

Natural variation in a population

Larger population requires a larger sample size

25
Q

Compare a representative sample to the population as a whole?

A

Should have the same mean value and the same variation about the mean

26
Q

What is random sampling?

A

Each individual has an equal chance of being selected

27
Q

What is systematic sampling?

A

Population is sampled at set intervals

28
Q

What is stratified sampling?

A

Sample is split and then divided proportionally

29
Q

What are 2 possible reasons for variation in experimental results?

A

Reliability of measurement

Natural variation of specimen

30
Q

How can the reliability of measuring instruments or procedures be determined?

A

By how consistent the results are

Reliability is increased by repeating measurements or readings

31
Q

What does the variation observed in an experiment indicate?

A

The precision of the measurement instrument or procedure.

It does not necessarily indicate accuracy

32
Q

What does accuracy mean when describing experimental measurements?

A

How close the data is to the true value

33
Q

What does the term precision mean when describing experimental measurements?

A

How close the data values collected are to the other data values collected

34
Q

How can the natural variation in living material be determined?

A

By taking a representative sample and calculating the mean

35
Q

What does the mean of a set of data give an indication of?

A

The true value of the total population

36
Q

What is an independent replicate?

A

When an experiment is repeated as a whole completely separate from the other experiment

37
Q

Why is an independent replicate required?

A

Results are only seen as being reliable if they can be achieved consistently in independent replicates