Unit 3 - Parental Nutrition 2 Flashcards
What are chambered bags?
Nutrition support in adults
- oral nutrition support
- enteral tube feeding
- parenteral nutrition
What are the advantages of using a central route to delivery parenteral nutrition?
Rapid and high flow delivery route
Long term use
What are the disadvantages of using a central route to delivery parenteral nutrition?
Air embolism
Pneumothorax
Central vein thrombosis
Cost of insertion
What are the advantages of using a peripheral route to delivery parenteral nutrition?
Short use
Easy insertion
Multiple insertion sites
What are the disadvantages of using a peripheral route to delivery parenteral nutrition?
Sepsis
Kinked lines
Thrombophlebitis
Insertion sites
What are the responsibilities of the parenteral nutrition pharmacist?
To ensure maximum chemical and physical compatibility and stability of all the constituents in a PN admixture
To provide a maximum guarantee of sterility of the finished product
To achieve a cost effective approach to the prescribed formulation
What are the stability issues surrounding parenteral nutrition?
Immediate use vs stored products
Prescription
Batch production
Individual vs standard
Home Parenteral Nutrition
Industrially vs Hospital compounded
What stability issues can affect Total Parenteral Nutrition?
More than 50 chemical entities
- interactions
Precipitation
Emulsion breakdown
Container materials
- PVC
- EVA
- multi-laminated
Environmental conditions
- light
- oxygen
- temperature
Drugs
What chemical concerns are there around parenteral nutrition?
Component stability
- amino acids
- vitamins
- lipids
Drugs
What physical concerns are there around parenteral nutrition?
Precipitation
- calcium-phosphate
- trace elements
Lipid emulsion
- breakdown
Drugs
What factors can cause the instability of vitamins?
Light
Oxygen
Interactions with plastics
