Unit 3 3.22

Question 1

Types of Mutation of DNA, list

Answer 1

-Chromosomal Alterations
-Point Mutations
-Deletions & Insertions
-Effect-on-Function Mutations
-Loss-of-Function
-Gain-of-Function
-Dominant Negative

Question 2

Chromosomal Alterations

Answer 2

-Deletions
-Duplications
-Insertions
-Inversions
-Translocations

Question 3

Point Mutation, 2 types are:

Answer 3

-Transition
-Tranversion

Question 4

Point Mutation - Transition

Answer 4

-exchange of a purine for a purine

Question 5

Point Mutation- Transversions

Answer 5

-exchange of purine for a pyrimidine

Question 6

Silent Mutation

Answer 6

-they code for the same amino acid will have no altered effect

Question 7

Missense mutation

Answer 7

minor or dramatic effect on protein

Question 8

nosense mutation

Answer 8

dramatic effect

Question 9

Deletion and Instertions

Answer 9

-Splice site
-Frameshift mutation

Question 10

Effect on function Mutations

Answer 10

-protein does not perform its function due to affected amino acid

Question 11

Loss-of Function

Answer 11

protein having less or no function

Question 12

Gain of Function

Answer 12

-protein having a new and abnormal function.

Question 13

Dominant negative mutation

Answer 13

have altered gene production that act in dominant manner. harmfull