UNIT 3 Flashcards
Surface area to volume ratio
•The surface area of an organism divided by its volume
•the larger the organism, the smaller the ratio
Factors
affecting gas
exchange
•diffusion distance
•surface area
•concentration gradient
•temperature
Ventilation
•Inhaling and exhaling in humans
• controlled by diaphragm and antagonistic interaction of internal and external intercostal muscles
Inspiration
• External intercostal muscles contract and internal relax
• pushing ribs up and out
• diaphragm contracts and flattens
• air pressure in lungs drops below atmospheric pressure as lung volume increases
• air moves in down pressure
gradient
Expiration
• External intercostal muscles relax and internal contract
• pulling ribs down and in
• diaphragm relaxes and domes
• air pressure in lungs increases above atmospheric pressure as lung volume decreases
• air forced out down pressure
gradient
Passage of gas
exchange
• Mouth / nose -> trachea -> bronchi -> bronchioles -> alveoli
• crosses alveolar epithelium into capillary endothelium
Alveoli
structure
• Tiny air sacs
• highly abundant in each lung - 300 million
• surrounded by the capillary network
• epithelium 1 cell thick
Why large
organisms need
specialised
exchange surface
• They have a small surface area to volume ratio
• higher metabolic rate - demands efficient gas exchange
• specialised organs e.g. lungs / gills designed for exchange
Fish gill
anatomy
• Fish gills are stacks of gill filaments
• each filament is covered with gill lamellae at right angles
How fish gas
exchange surface
provides large
surface area
• Many gill filaments covered in many gill lamellae are positioned at right angles
• creates a large surface area for efficient diffusion
Countercurrent
flow
• When water flows over gills in opposite direction to flow of blood in capillaries
• equilibrium not reached
• diffusion gradient maintained across entire length of gill lamellae
Name three
structures in
tracheal system
• Involves trachea, tracheoles, spiracles
How tracheal
system provides
large surface area
• Highly branched tracheoles
• large number of tracheoles
• filled in ends of tracheoles moves into tissues during exercise
• so larger surface area for gas exchange
Fluid-filled
tracheole ends
• Adaptation to increase movement of gases
• when insect flies and muscles respire anaerobically- lactate produced
• water potential of cells lowered, so water moves from tracholes to cells by osmosis
• gases diffuse faster in air
How do insects
limit water loss
• Small surface area to volume ratio
• waterproof exoskeleton
• spiracles can open and close to reduce water loss
• thick waxy cuticle - increases diffusion distance so less evaporation
Dicotyledonous
plants leaf
tissues
• Key structures involved are mesophyll layers
• (palisade and spongy mesophyll)
• stomata created by guard cells
Gas exchange
in plants
• Palisade mesophyll is site of photosynthesis
• oxygen produced and carbon dioxide used creates a concentration gradient
• oxygen diffuses through air space in spongy mesophyll and diffuse out stomata
Role of guard
cells
• swell - open stomata
• shrink - closed stomata
• at night they shrink, reducing water loss by evaporation
Xerophytic
plants
• Plants adapted to survive in dry environments with limited water (e.g. marram grass/cacti)
• structural features for efficient gas exchange but limiting water loss
Adaptations of
xerophyte
• Adaptations to trap moisture to increase humidity -> lowers water potential inside plant so less water lost via osmosis
• sunken stomata
• curled leaves
• hairs
• thick cuticle reduces loss by evaporation
• longer root network
Digestion
• Process where large insoluble biological molecules are hydrolysed into smaller soluble molecules
• so they can be absorbed across cell membranes
Locations of
carbohydrate
digestion
• Mouth -> duodenum -> ileum
Locations of
protein
digestion
• Stomach -> duodenum -> ileum
Endopeptidases
• Break peptide bonds between amino acids in the middle of the chain
• creates more ends for exopeptidases for efficient hydrolysis
Exopeptidases
• Break peptide bonds between amino acids at the ends of polymer chain
Membrane-
bound
dipeptidases
• Break peptide bond between two amino acids
Digestion of
lipids
• Digestion by lipase (chemical)
• emulsified by bile salts (physical)
• lipase produced in pancreas
• bile salts produced in liver and stored in gall bladder
Lipase
• Produced in pancreas
• Breaks ester bonds in triglycerides to form :
• monoglycerides
• glycerol
• fatty acids
Role of bile
salts
• Emulsify lipids to form tiny droplets and micelles
• increases surface area for lipase action - faster hydrolysis
Micelles
• Water soluble vesicles formed from fatty acids, glycerol, monoglycerides and bile salts
Lipid
absorption
• Micelles deliver fatty acids, glycerol and monoglycerides to epithelial cells of ileum for absorption
• cross via simple diffusion as lipid-soluble and non-polar
Lipid
modification
• Smooth ER reforms monoglycerides / fatty acids into tryglycerides
• golgi apparatus combines tryglycerides with proteins to form vesicles called chylomicrons
How lipids enter
blood after
modification
• Chylomicrons move out of cell via exocytosis and enter lacteal
• lymphatic vessels carry chylomicrons and deposit them in bloodstream
Haemoglobin
(Hb)
• Quaternary structure protein
• 2 alpha chains
• 2 beta chains
• 4 associated haem groups in each chain.
containing Fe2+
• transports oxygen
Affinity of
haemoglobin
• The ability of haemoglobin to attract / bind to oxygen
Saturation of
haemoglobin
• When haemoglobin is holding the maximum amount of oxygen it can hold
Loading /
unloading of
haemoglobin
• Binding/detachment of oxygen to haemoglobin
• also known as association and disassociation
Oxyhaemoglobin
dissociation
curve
• oxygen is loaded in regions with high partial pressures (alveoli)
• unloaded in regions of low partial pressure (respiring tissue)
Oxyhaemoglobin
dissociation curve
shifting left
• Hb would have a higher affinity for oxygen
• load more at the same partial pressure
• becomes more saturated
• adaptation in low-oxygen environments
• e.g. llamas/ in foetuses
•
Cooperative
binding
• Hb’s affinity for oxygen increases as more oxygen molecules are associated with it
• when one binds, Hb changes shape meaning others bind more easily
• explaining S shape of curve
How carbon
dioxide affects
haemoglobin
• When carbon dioxide dissolves in liquid, carbonic acid forms
• decreases pH causing Hb to change shape
• affinity decreases at respiring tissues
• more oxygen is unloaded
Bohr effect
• High carbon dioxide partial pressure
• causes oxyhaemoglobin curve to shift to the right
Oxyhaemoglobin
dissociation curve
shifting right
• Hb has lower affinity for oxygen
• unloads more at the same partial pressures
• less saturated
• present in animals with faster metabolisms that need more oxygen for respiration
• e.g. birds/rodents
•
Closed
circulatory
system
• Blood remains within blood vessels