Unit 2 - Topic 15 - Microorganisms, Defence Against Disease, Medicine and Drugs Flashcards
What are the three main types of microbe?
Bacteria
Viruses
Fungi
What is a pathogen?
A disease causing micro-organism.
Who disproved the theory of spontaneous generation?
Louis Pasteur
What experiment did Pasteur carry out to disprove the spontaneous generation theory?
Swan neck experiment
What did the theory of spontaneous generation propose?
Spontaneous generation theory assumed that micro-organisms spontaneously appeared from non-living material.
Describe the apparatus used in Pasteur’s swan neck experiment and the results he obtained.
- Sterilised broth was placed into a number of sterilised flasks.
- Some had ‘swan neck’ openings, and others had the neck removed (controlled variable).
- The broth was left for a few weeks, but the broth in the ‘swan neck’ flasks was not contaminated.
- The broth in the open flasks was contaminated.
Conclusion
- Microbes were trapped in the ‘swan neck’ and could not reach the broth, but microbes could gain entry in the open flask.
Therefore, microbes could only contaminate fluids and solid foods if they were already present or could gain access to the samples.
What were the controlled variables in Pasteur’s ‘swan neck’ experiment?
- Type of broth used
- Temperature
- Time
- Volume of broth
What is pasteurisation?
This is a technique to reduce contamination of milk and other products.
- The milk is heated to a high temperature, but below boiling point.
- It is then rapidly chilled to a low temperature.
- Pasteurisation kills most bacteria present.
Give an example of a virus
- HIV –> AIDS
- Rubella
- Measles
- Mumps
- Colds and flu
- Polio
Give an example of a bacterium
- Salmonella food poisoning
- Gonorrhoea
- Tuberculosis
- Chlamydia
Give an example of a fungus
• Athlete’s foot
How do antibodies aid in the defence against disease?
- Stop the pathogen spreading (immobilisation).
- Stops the pathogen from reproducing.
- Easier for phagocytosis (clumped together).
What type of microbe is HIV, how is it spread and how is it controlled/prevented/treated?
Type
- Virus
Spread
- Exchange of body fluids during sex
- Infected blood
Control/prevention/treatment
- Using a condom
- Drug addicts not sharing needles
- No cure
What type of microbe is Rubella, how is it spread and how is it controlled/prevented/treated?
Type
- Virus
Spread
- Airborne (droplet infection) through coughing and sneezing
Control/prevention/treatment
- Prevented by MMR vaccination
What type of microbe is Measles, how is it spread and how is it controlled/prevented/treated?
Type
- Virus
Spread
- Airborne (droplet infection) through coughing and sneezing
- Contact
Control/prevented/treatment
- Prevented by MMR vaccination
What type of microbe is Mumps, how is it spread and how is it controlled/prevented/treated?
Type
- Virus
Spread
- Airborne (droplet infection) through coughing and sneezing
Control/prevention/treatment
- Prevented by MRR vaccination
What type of microbe are Colds and flu, how are they spread and how are they controlled/prevented/treated?
Type
- Virus
Spread
- Airborne (droplet infection) through coughing and sneezing
Control/prevention/treatment
- Flu vaccination for targeted groups
What type of microbe is Polio, how is it spread and how is it controlled/prevented/treated?
Type
- Virus
Spread
- Usually spread through drinking water contaminated with faeces
Control/prevention/treatment
- The Polio vaccination has currently eradicated Polio in the UK
What type of microbe is Salmonella food poisoning, how is it spread and how is it controlled/prevented/treated?
Type
- Bacterium
Spread
- Cross contamination of food
Control/prevention/treatment
- Always cooking food thoroughly and not mixing cooked and uncooked foods
- Treatment by antibiotics
What type of microbe is Gonorrhoea, how is it spread and how is it controlled/prevented/treated?
Type
- Bacterium
Spread
- Sexual contact
Control/prevention/treatment
- Using a condom
- Treatment by antibiotics
What type of microbe is Tuberculosis, how is it spread and how is it controlled/prevented/treated?
Type
- Bacterium
Spread
- Airborne (droplet infection) through coughing and sneezing
Control/prevention/treatment
- BCG vaccination
- If contracted, treated with drugs including antibiotics
What type of microbe is Chlamydia, how is it spread and how is it controlled/prevented/treated?
Type
- Bacterium
Spread
- Sexual contact
Control/prevention/treatment
- Condom
- Antibiotics
What type of microbe is Athlete’s foot, how is it spread and how is it controlled/prevented/treated?
Type
- Fungus
Spread
- Contact
Control/prevention/treatment
- Avoid direct contact in areas where spores are present
- Treated with fungicide
Describe some of the defence mechanisms of the body
The body’s first line of defence.
The body’s first line of defence includes physical and chemical barriers that are always ready to protect the body from infection.
- Skin, physical barrier to microbes trying to gain entry.
- Mucous membranes, thin membranes in nasal cavity and respiratory system that trap and expel microbes. (The microbes are trapped in the mucous lining of the membranes).
- Clotting, closes open wounds quickly to prevent microbes gaining entry into your circulatory system, also prevents the loss of blood.
- Tears, wash out invading pathogens, contain lysozyme enzyme which breaks down micro-organisms.
- Stomach acid, hydrochloric acid present in the gastric juices kill any unwanted pathogens.
- Urinary track, the flow of urine ‘flushes’ out invading microbes.