Unit 2, Topic 1 Homeostasis — thermoregulation and osmoregulation Flashcards

Nervous system, endocrine system, thermoregulation, osmoregulation

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1
Q

What is homeostasis, and why is it important for living organisms?

A

Homeostasis is the process by which living organisms maintain a stable internal environment despite changes in external conditions. It is crucial for the proper functioning of cells and organs, ensuring that factors like temperature, pH, and fluid balance remain within narrow limits.

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2
Q

How does the nervous system use negative feedback to maintain homeostasis?

A

Negative feedback mechanisms involve detecting a change (stimulus), processing it in the control center (e.g., brain or spinal cord), and triggering a response to counteract the change, returning the system to its optimal state. For example, if body temperature rises, responses like sweating and vasodilation are activated to cool the body down.

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3
Q

What are sensory receptors, and what types are there?

A

Sensory receptors are specialized cells that detect specific stimuli and convert them into electrical signals. Types include:

Chemoreceptors: Detect chemical changes (e.g., taste, smell, blood composition).

Thermoreceptors: Detect temperature changes (e.g., skin, hypothalamus).

Mechanoreceptors: Detect mechanical stimuli (e.g., pressure, touch, vibration).

Photoreceptors: Detect light (e.g., rods and cones in the retina).

Nociceptors: Detect pain (e.g., extreme temperatures, mechanical damage).

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4
Q

What is the role of neurons in the nervous system?

A

Neurons are the fundamental units of the nervous system responsible for transmitting electrical and chemical signals. They include:

Sensory/Afferent Neurons: Carry information from sensory receptors to the CNS.
Interneurons: Connect sensory and motor neurons within the CNS and process information.

Motor/Efferent Neurons: Transmit signals from the CNS to effectors like muscles or glands.

Tip: Afferent- think the CNS welcoming the sensory neuron from receptors like “Ahh”, Efferent- think CNS pushing away motor neuron to effectors like “eff off”

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5
Q

What are the main structures of a neuron and their functions?

A

Dendrites: Receive signals from other neurons or sensory receptors.
Soma (Cell Body): Integrates signals and generates action potentials.
Axon: Conducts electrical impulses away from the soma.
Myelin Sheath: Insulates the axon, increasing signal transmission speed.
Nodes of Ranvier: Gaps in the myelin sheath that allow saltatory conduction.
Axon Terminal: Converts electrical signals into chemical signals and releases neurotransmitters into the synapse.

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6
Q

What is the resting potential of a neuron, and how is it maintained?

A

The resting potential is the stable electrical charge difference across the neuronal membrane when not transmitting an impulse, typically around -70 mV. It is maintained by the sodium-potassium pump, which moves 3 sodium ions out and 2 potassium ions into the cell, and by potassium channels that allow potassium to leak out.

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7
Q

How is an action potential transmitted along a neuron?

A

An action potential is an electrical signal that travels down the axon. It starts when the membrane potential reaches a critical threshold, triggering sodium channels to open and sodium ions to enter, causing depolarization. Potassium channels then open, allowing potassium to exit, repolarizing the membrane.

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8
Q

What occurs during synaptic transmission?

A

When an action potential reaches the axon terminal, it triggers calcium channels to open, allowing calcium ions to enter. This causes neurotransmitters to be released into the synaptic cleft, where they bind to receptors on the postsynaptic neuron, generating a response that may lead to a new action potential or inhibit the neuron.

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9
Q

How does signal transduction occur in the postsynaptic neuron?

A

Neurotransmitter binding to receptors on the postsynaptic neuron can lead to depolarization (exciting the neuron) or hyperpolarization (inhibiting the neuron). This converts the chemical signal back into an electrical signal, allowing the continuation of the nerve impulse or modulation of the response. Neurotransmitters are then broken down or reabsorbed to end the signal.

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10
Q

What role does the endocrine system play in maintaining homeostasis?

A

The endocrine system uses negative feedback mechanisms to regulate physiological processes in response to internal and external stimuli.

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11
Q

What is negative feedback in the context of homeostasis?

A

Negative feedback is a process that helps keep things balanced inside the body. When something changes, it triggers a response that works to bring things back to normal, preventing the change from going too far.

For example: When your body temperature rises (e.g. due to exercise or hot weather), your brain detects the increase. In response, it triggers cooling mechanisms like sweating and increasing blood flow to the skin. These actions help lower your body temperature back to its normal range. Once the temperature is back to normal, the brain reduces these cooling actions. This process of detecting a change, initiating a response to counteract it, and then adjusting the response as needed is an example of negative feedback.

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12
Q

How does the stimulus-response model operate in the endocrine system?

A

The stimulus-response model starts with a stimulus (e.g., a change in blood glucose levels), detected by receptors. The information is sent to an endocrine gland, which releases hormones into the bloodstream. These hormones travel to target cells or organs to restore balance and maintain homeostasis.

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13
Q

Provide an example of negative feedback involving blood glucose levels.

A

e.g. After a meal, if blood sugar rises, the pancreas releases insulin to facilitate glucose uptake by cells, reducing blood sugar levels. Once normal levels are restored, insulin secretion decreases. Conversely, if blood sugar levels fall, the pancreas releases glucagon to stimulate glucose release from the liver, increasing blood sugar levels.

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14
Q

What are hormones, and how do they affect target cells?

A

Hormones are chemical messengers secreted by endocrine glands into the bloodstream or lymphatic fluid. They affect target cells by binding to specific receptors, triggering cellular changes such as altering gene expression, regulating enzyme activity, or modifying membrane permeability.

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15
Q

How do cells regulate their sensitivity to hormones?

A

Cells regulate sensitivity by upregulating or downregulating (increasing or decreasing) the number of receptors for a hormone on or in a cell depending on the type of hormone (if the hormone is water soluble it will be on the surface, if it is fat soluble it will be in the cell). High hormone levels can lead to a reduction in receptor numbers to prevent overstimulation, while low hormone levels can lead to an increase in receptor numbers to enhance response.

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16
Q

What are endotherms?

A

Endotherms are animals that maintain a stable internal body temperature through internal heat production, regardless of external conditions.

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17
Q

What is brown adipose tissue and its role in endotherms?

A

Brown adipose tissue is rich in mitochondria and generates heat through non-shivering thermogenesis to help maintain body temperature in cold conditions.

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18
Q

How does insulation help endotherms?

A

Insulation, such as fur, feathers, or subcutaneous fat, reduces heat loss by trapping a layer of air close to the skin, providing a barrier against the cold.

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19
Q

What is kleptothermy?

A

Kleptothermy is a behavioural adaptation where animals share or steal heat from other organisms, such as huddling together for warmth.

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20
Q

What is hibernation?

A

Hibernation is a state of prolonged torpor during cold months where metabolic rate and body temperature drop significantly to conserve energy.

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21
Q

What is aestivation?

A

Aestivation is a state similar to hibernation but occurs during hot or dry periods to avoid heat stress.

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22
Q

What is torpor?

A

Torpor is a short-term reduction in body temperature and metabolic rate, allowing animals to save energy when food is scarce or during extreme temperatures.

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23
Q

How do endotherms regulate body heat through evaporative heat loss?

A

Endotherms use evaporative heat loss through sweating or panting, which cools the body by releasing moisture that evaporates from the skin or respiratory surfaces.

24
Q

What is the role of vasomotor control in thermoregulation?

A

Vasomotor control involves vasodilation and vasoconstriction. Vasodilation increases blood flow and heat loss, while vasoconstriction reduces blood flow to conserve heat.

25
Q
A
26
Q

How does thermoregulation work in humans?

A

In humans, thermoregulation involves sweating for cooling, shivering for heat generation, vasodilation to release heat, and vasoconstriction to retain warmth. The hypothalamus controls these processes through feedback loops.

27
Q

What happens when the body temperature rises in humans?

A

The hypothalamus detects the rise in temperature and triggers sweating and vasodilation to cool the body down.

28
Q

What happens when the body temperature drops in humans?

A

The hypothalamus detects the drop in temperature and triggers shivering and vasoconstriction to generate and conserve heat.

29
Q

What is osmoregulation in humans?

A

Osmoregulation is the process by which humans maintain the balance of water and electrolytes within their bodies, crucial for homeostasis.

30
Q

What role do the kidneys play in osmoregulation?

A

The kidneys filter blood, reabsorb needed substances, and excrete excess water and waste as urine.

31
Q

What is the function of antidiuretic hormone (ADH) in osmoregulation?

A

ADH, released by the pituitary gland, signals the kidneys to reabsorb more water by making the collecting ducts more permeable through aquaporins, reducing urine output and concentrating the urine.

32
Q

What happens when the body detects high blood osmolarity?

A

ADH is released to increase water reabsorption by the kidneys, reducing urine output and concentrating the urine.

33
Q

What occurs when blood osmolarity is low?

A

ADH secretion decreases, leading to fewer aquaporins, less water reabsorption, and more dilute urine.

34
Q

How do plants maintain water balance?

A

Plants maintain water balance through structural mechanisms like stomata, vacuoles, and the cuticle, as well as by regulating water loss and storage.

35
Q

What is the role of stomata in plants?

A

Stomata are small pores on leaf surfaces that regulate gas exchange and water loss.

36
Q

How do guard cells regulate stomatal function?

A

Guard cells control the opening and closing of stomata to balance the plant’s need for carbon dioxide with water conservation.

37
Q

What is the function of vacuoles in plant cells?

A

Vacuoles store water and maintain turgor pressure, which is important for structural support.

38
Q

What is the role of the cuticle in plants?

A

The cuticle is a waxy layer on leaves and stems that reduces water loss by acting as a barrier to evaporation.

39
Q

What is abscisic acid (ABA) and its role in plants?

A

ABA is a plant hormone that signals stomatal closure during water stress, helping to conserve water.

40
Q

How does ABA affect stomatal function?

A

ABA binds to receptors on guard cells, triggering a biochemical response that leads to the closure of stomata and reduced transpiration.

41
Q

How do stomata vary in plants adapted to different environments?

A

Plants in arid environments often have fewer stomata or stomata on the underside of leaves, while plants in wetter environments may have more stomata to maximize gas exchange.

42
Q

Muscles and glands as part of the stimulus response model are:

A

effectors (the end part of the model)

43
Q

In general, what is required for a target cell to be activated by a hormone?

A

The target cell must have specific receptors for the hormone.

44
Q

What is the interneuron?

A

Interneurons are a type of neuron that are located between sensory and motor neurons. They make up the majority of neurons in the body and play a crucial role in integrating sensory information and regulating motor activity.

45
Q

Which neuron has it’s cell body (soma) off to the side, in the middle of the axon?

A

The sensory neuron. Interneurons’ soma are between short axons and large dendrites but do not reside off to the side.

46
Q

Why will guard cells close on a hot and dry day?

A

When full of water, guard cells open, when dry, they close. This is to prevent water loss by transpiration.

47
Q

What is a stimulus response model?

A

Stimulus-receptor-sensory/afferent neuron-Central Nervous System-motor/efferent neuron-effector-response

48
Q

If the response increases the stimulus is the feedback negative of positive?

A

Positive feedback (think “more! more!)

48
Q

If the response reduces the stimulus is the feedback negative of positive?

A

Negative feedback (think “stoppp!”)

49
Q

Describe the role of osmoreceptors in maintaining water balance.

A

When osmoreceptors detect an increase/decrease in osmolarity, ADH production is increased/ decreased, respectively.

50
Q

Explain signal transduction.

A
  1. Reception- detection of signaling molecule by receptor
  2. Transduction- relay of signal into cell
  3. Cellular response- activation of cellular activity or process
51
Q

How is abscisic acid related to the slowing of water loss in plants?

A

Causes closure of leaf stomata and shedding of leaves resulting in a reduction of both water loss by simple diffusion and surface area exposed to dry air.

52
Q

What is kleptothermy?

A

Kleptothermy is any form of thermoregulation by which an animal shares in the metabolic thermogenesis of another animal. One form is huddling.

53
Q

Define piloerection in relation to thermoregulatory mechanisms.

A

Piloerection, “goosebumps,” is a thermoregulatory mechanism in which small muscles at the base of hair follicles contract, causing the hairs to stand upright. In response to cold temperatures, piloerection helps to trap a layer of air close to the skin, providing additional insulation and reducing heat loss. This response is controlled by the autonomic nervous system and is part of the body’s effort to maintain a stable internal temperature in cooler environments.

54
Q

Shivering thermogenesis?

A

A thermoregulatory mechanism where involuntary, rapid muscle contractions generate heat in response to cold exposure. This process increases the metabolic rate and produces heat as a byproduct, helping to raise body temperature when it drops below the normal range. Shivering is triggered by the hypothalamus, which detects changes in body temperature and signals the muscles to contract rhythmically, effectively converting chemical energy into thermal energy to maintain homeostasis.

55
Q

What is torpor?

A

Torpor is a state of reduced physiological activity in animals characterized by a significant decrease in metabolic rate, body temperature, heart rate, and respiratory rate. This state allows animals to conserve energy and water, especially during periods of cold weather or food scarcity. Torpor can be short-term (daily torpor) or long-term (hibernation in winter or estivation in extreme heat).

56
Q

Explain the process of action potential? (4 steps)

A

1) Depolarization: activated sodium channels, deactivated potassium channels, 2) Repolarization: inactivated sodium channels, activated potassium channels, 3) Hyperpolarization: moving back to activation for the sodium channels, activated potassium channels, 4) Resting state: both sodium and potassium channels deactivated.

extra detail- Hypopolarization is the initial increase of the membrane potential to the value of the threshold potential. The threshold potential opens voltage-gated sodium channels and causes a large influx of sodium ions. This phase is called the depolarization. During depolarization, the inside of the cell becomes more and more electropositive, until the potential gets closer the electrochemical equilibrium for sodium of +61 mV. This phase of extreme positivity is the overshoot phase.

After the overshoot, the sodium permeability suddenly decreases due to the closing of its channels. The overshoot value of the cell potential opens voltage-gated potassium channels, which causes a large potassium efflux, decreasing the cell’s electropositivity. This phase is the repolarization phase, whose purpose is to restore the resting membrane potential. Repolarization always leads first to hyperpolarization, a state in which the membrane potential is more negative than the default membrane potential. But soon after that, the membrane establishes again the values of membrane potential