Unit 2: HEMATOPOIESIS Flashcards
During the second trimester of fetal development, the primary site of blood cell production is what organ?
Liver
It is the predominant hemoglobin in fetus
HbF
Bone marrow aspiration in adults
Iliac crest
Only site for production and development of blood cells at birth
Bone marrow
The process of formation and development of blood cells is:
Hematopoiesis
What organ is the site of sequestration of platelets?
Spleen
It is the first fully developed organ in the fetus
Thymus
Macrophage that remove senescent cells and foreign debris from blood that circulates through the liver
Kupffer cell
The removal of senescent RBCs by the removal of abnormal parts only is termed as?
Pitting
It provides nutrients for the osseous bone and the marrow
Periosteal artery
It is the primary site of blood cell production during myeloid phase
Bone marrow
Definitive hematopoiesis begins at what phase?
Hepatic phase
In what phase does lymphoid cell begins to appear?
Hepatic phase
Hematopoietically inactive marrow composed primarilly of adipocytes
Yellow marrow
The term used for replacement of active marrow into adipose tissue
Retrogression
It is the site of blood cell production during 2nd trimester
Liver
Production of megakaryocytes begins during what phase?
Hepatic phase
The fluid portion of blood that escapes into the connective tissue and is characterized by a low protein concentration and the absence of RBCs
Lymph
Composed of extravascular cords that contain all the developing blood cell lineage, stem and progenitor cells, adventitial cells and macrophages and are active
Red marrow
What organ is responsible for the maturation of T lymphocytes and regulation of their expression of CD4 and CD8
Thymus
What are the Hematopoietic theories?
*Monophyletic Theory
*Dualistic Theory
*Polyphyletic Theory
Bone marrow arteries
*Nutrient artery
*Periosteal artery
Adult Hematopoietic tissues
*Bone marrow
*Thymus
*Spleen
*Liver
*Lymph nodes
