Unit 2: HEMATOPOIESIS

Question 1

During the second trimester of fetal development, the primary site of blood cell production is what organ?

Answer 1

Liver

Question 2

It is the predominant hemoglobin in fetus

Answer 2

HbF

Question 3

Bone marrow aspiration in adults

Answer 3

Iliac crest

Question 4

Only site for production and development of blood cells at birth

Answer 4

Bone marrow

Question 5

The process of formation and development of blood cells is:

Answer 5

Hematopoiesis

Question 6

What organ is the site of sequestration of platelets?

Answer 6

Spleen

Question 7

It is the first fully developed organ in the fetus

Answer 7

Thymus

Question 8

Macrophage that remove senescent cells and foreign debris from blood that circulates through the liver

Answer 8

Kupffer cell

Question 9

The removal of senescent RBCs by the removal of abnormal parts only is termed as?

Answer 9

Pitting

Question 10

It provides nutrients for the osseous bone and the marrow

Answer 10

Periosteal artery

Question 11

It is the primary site of blood cell production during myeloid phase

Answer 11

Bone marrow

Question 12

Definitive hematopoiesis begins at what phase?

Answer 12

Hepatic phase

Question 13

In what phase does lymphoid cell begins to appear?

Answer 13

Hepatic phase

Question 14

Hematopoietically inactive marrow composed primarilly of adipocytes

Answer 14

Yellow marrow

Question 15

The term used for replacement of active marrow into adipose tissue

Answer 15

Retrogression

Question 16

It is the site of blood cell production during 2nd trimester

Answer 16

Liver

Question 17

Production of megakaryocytes begins during what phase?

Answer 17

Hepatic phase

Question 18

The fluid portion of blood that escapes into the connective tissue and is characterized by a low protein concentration and the absence of RBCs

Answer 18

Lymph

Question 19

Composed of extravascular cords that contain all the developing blood cell lineage, stem and progenitor cells, adventitial cells and macrophages and are active

Answer 19

Red marrow

Question 20

What organ is responsible for the maturation of T lymphocytes and regulation of their expression of CD4 and CD8

Answer 20

Thymus

Question 21

What are the Hematopoietic theories?

Answer 21

*Monophyletic Theory
*Dualistic Theory
*Polyphyletic Theory

Question 22

Bone marrow arteries

Answer 22

*Nutrient artery
*Periosteal artery

Question 23

Adult Hematopoietic tissues

Answer 23

*Bone marrow
*Thymus
*Spleen
*Liver
*Lymph nodes