Unit 2 - Central Nervous System Flashcards
What does the cerebellum do?
coordinate movement and balance
What does the neural plate in the early embryo develop to be?
CNS
What is neural crest?
will migrate throughout body and contribute to many structures, including peripheral nervous system
What does the forebrain consist of?
diencephalon and cerebrum
What does the hindbrain consist of?
medulla oblongata and cerebellum and pons
What protects and supports the CNS?
- surrounded by bony cage (cranium protecting the brain, vertebrae protecting the spine)
- three layers of connective tissue (meninges, surrounds the brain and spinal cord_
- fluid between layers (cerebrospinal fluid)
What is Meninges?
3 layers of membrane: Dura mater, Arachnoid membrane, Pia mater)
-lies between the bones and tissues of the CNS
-stabilizes the neural tissue and protects it from bruising against the bones of the skeleton
What is Dura mater?
the thickest of 3 membranes
- associated with veins that drain blood from brain through vessels or cavities called sinuses
What is Arachnoid membrane?
the middle layer, is loosely tied to the inner membrane, leaving a subarachnoid space between the two layers
What is Pia mater?
the inner membrane, a thin layer that adheres to the surface of the brain and spinal cord
- arteries that supply blood to the brain are associated with this layer
Where is cerebrospinal fluid located?
found in ventricles and in the space between pia mater and arachnoid membrane
Where is interstitial fluid located?
found inside pia mater
What is the mammalian CNS surrounded by?
meninges
What are the fluid-filled cavities in the CNS?
lateral ventricles (1st and 2nd ventricles), third ventricle within the brain and the central canal within spinal cord
What is the cerebrospinal fluid in ventricles continuous with?
continuous with fluid in central canal of spinal cord
What is cerebrospinal fluid secreted by?
choroid plexus, a specialized region on the walls of the ventricle secrets CSF within each ventricle
- also transports ions and nutrients from blood to cerebrospinal fluid
What are the extracellular fluids of the CNS?
interstitial fluid, plasma, cerebrospinal fluid (CSF)
What are the extracellular fluids of the CNS?
interstitial fluid, plasma, cerebrospinal fluid (CSF)
Where is interstitial fluid located?
outside blood vessels between cells, and surrounds neurons and glial cells
Where is plasma located?
within cerebral blood vessels
Where is cerebrospinal fluid located?
within the ventricular system, it bathes external surfaces of brain, between meninges
compared to plasma, CSF has lower K+, Ca2+, HCO3-, glucose, pH, similar Na+
it also has very low protein and no blood cells; presence of blood cells or protein in CSF suggests infection
How is CSF reabsorbed into venous blood?
CSF is reabsorbed into venous blood by arachnoid villi (goes from high pressure to lower pressure) then goes to the heart
1. from ventricles, CSF flows into subarachnoid space
2. the CSF flows around neural tissue and is finally absorbed back into the blood by special villi
What does the astrocyte do?
wraps their feet around blood vessels
What do astrocyte foot processes do?
secrete paracrine factors that promote tight junction formation
Why are tight junctions important?
prevents solute movement between endothelial cells
What is the blood-brain barrier?
isolates brain from harmful substances in the blood and from blood-borne pathogens