Unit 2 - Cell/Tissue Injury & Inflammation Flashcards
1
Q
What is innate immunity?
A
- immediate
- non-specific
2
Q
What is adaptive immunity?
A
- slower time to generate
- higher specificity
3
Q
What is TLR and what do they recognize?
A
Toll-like receptors and they recognize PAMPs (Pathogen )
4
Q
Where are TLRs present?
A
Macrophages and dendritic cells
5
Q
Once binding to a PAMP, what does TLR activate? What does this do?
A
- NF-kB
- Activates immune response genes that leads to production of multiple immune mediators
