Unit 2 Flashcards
How common is chondrosarcoma?
3 MC malignancy of bone
Where does chondrosarcoma arise from?
Malignant tumor of chondrogenic origin arising from chondroblasts and collagenoblasts
What is the speed for chondrosarcoma?
Typically slow growing and metastasizes late
Chondrosarcoma is the most common primary malignant bone tumor in what locations?
Hand
Sternum
Scapula
With chondrosarcoma primary and secondary can metastasize to where?
The lungs
What is secondary chondrosarcoma due to the malignant degeneration of?
Enchondroma
Osteochondroma
Where are the primary chondrosarcoma from?
MC overall from central (medullary)
Peripheral from osseous stalk projecting from bone
What are central lesions of chondrosarcoma classified by?
Tissue type as conventional, clear cell and mesenchymal
What are conventional lesions of chondrosarcoma classified by?
Conventional tumors are sub classified by low, medium, or high grade aggressiveness.
More than 90% are classified as this
What is the most common complaint for chondrosarcoma?
Progressive but not debilitating in the hips and buttocks of more than 3mo duration
What are the symptoms of chondrosarcoma?
Pain occurs at night, not alleviated w/ rest
Pain tends to occur late
Intitial complaint may be pain or swelling
Pelvic lesions can become large before discovered
What are the MC locations of chondrosarcoma?
Pelvis
Proximal femur
Proximal humerus
Distal femur
How does chondrosarcoma usually present on radiographs?
Usually demonstates a large, radiolucent lesion w/ poorly defined margins.
May see permeative pattern of destruction
Cortex may be thick or thin
Expansion and endosteal scalloping
Rings
If calcification is lacking what might chondrosarcoma mimic?
Giant cell tumor
Osteolytic metastasis
Plasmacytoma
In a sacral location, what might chondrosarcoma mimic?
Chordoma
Osteolytic metastasis
