Unit 2 Flashcards
Somatic PNS
Innervates skin, joints, muscles
Visceral PNS
AKA autonomic nervous system, innervates internal organs, blood vessels, glands
PNS sends _____ information from to body to the CNS
Sensory
Central nervous system
Brain (brain stem, cerebellum, cerebrum) and spinal cord
Why do rats have larger olfactory bulbs?
They depend more on a sense of smell
Three major subsections of the brain
Prosencephalon, mesencephalon, rhombencephalon
Subsections of prosencephalon and what they consist of
Telencephalon
Diencephalon (thalamus!)
Subsections of rhombencephalon and what they consist of
Metencephalon (cerebellum)
Myelencephalon (brain stem)
Number of spinal nerve pairs
31
Function of the spinal cord
Conduit of motor and sensory information between the brain and the body
Dorsal root is ______ while ventral root is ______
Sensory; motor
Cell bodies for dorsal root are in _____ while cell bodies for ventral root are in ______
ganglion; ventral horn
Ascending sensory pathways
Touch pathway via dorsal column, spinothalamic tract (pain)
Descending motor pathways
Lateral pathway and ventromedial pathway
Why are tracts lighter in color?
MYELIN
Three layers of meninges
Dura mater, arachnoid membrane, pia mater
Space between arachnoid membrane and pia mater
Subarachnoid space
Subdural hematoma
Rupture of blood vessels and blood collects between dura and arachnoid which can lead to brain injury and death
Gyrus
Bumps on the cerebrum surface
Sulcus
Grooves in the cerebrum surface
Fissure
especially deep groove in the cerebrum surface (super deep sulcus)
Corpus callosum
Underneath upper cortex; white matter that connects the two hemispheres
Central Sulcus
Separates frontal and parietal lobe
Longitudinal cerebral fissure
Separates the two hemispheres of the telencephalon
Four lobes (plus one special one)
- Frontal
- Parietal (somatosensory)
- Occipital (vision)
- Temporal (auditory)
- Insula (taste and emotional context)
Precentral gyrus function
Motor cortex
Postcentral gyrus function
Somatosensory cortex
Superior temporal gyrus function
Auditory cortex
What are association areas?
Areas of the brain that interpret motor AND sensory functions
Corticospinal pathway
- UMN (cell body in pre-central gyrus)
- Axons pass through
1. Internal capsule
2. Cerebral peduncle (midbrain)
3. Pyramids (medulla; decussate here)
Sensory vs Motor Cranial Nerves
Sensory: carrying information TO the CNS (skin, muscles, organs)
Motor: carrying information FROM the CNS (not just somatic, but could also be autonomic)
Ventricular system
- Brain floats in CSF
- Ventricles are CSF filled caverns and canals inside the brain
Choroid Plexus
Tissue that secretes CSF
Septum Pellucidum
Tissue/vertical membrane that separates the anterior horns of the lateral ventricles
How much CSF gets made in one day?
1 pint
Where does CSF go?
Gets absorbed in subarachnoid space into blood
Hydrocephalus
AKA water on the brain - when CSF flow through the ventricular system to subarachnoid space is impaired; usually treated by surgically implanting a shunt which drains fluid to abdomen
Medulla oblangata functions
- dorsomedial medulla contains sensory relay nuclei
- contains a number of nuclei crucial for vital functions
- all tracts to and from the SC
Pons functions
Several nuclei mediating hearing, vestibular, and taste functions, several tracts and pontine reticular formation (sleep and arousal)
Cerebellum functions
Fine motor control
Tectum functions
- Midbrain
- Superior colliculus: visual information
- Inferior colliculus: auditory information
- teCtum = ceiling = dorsal
Tegmentum functions
- Midbrain
- Substantia nigra (dopamine producing cells in PD)
-Reticular formation - teGmentum - ground - ventral
Periaqueductal gray functions
- Midbrain
- Modulation of pain
Thalamus functions
- Dorsal part of diencephalon
- relays most types of sensory information to neocortex (vision, hearing, pain, touch, temperature, and proprioception)
Hypothalamus functions
- Ventral part of diencephalon
- Control autonomic NS
- control of motivated behaviors (eating, drinking, sex)
- controls endocrine systems (pituitary gland)
Fornix function
Output of hippocampus to mammillary bodies
Nerve
Collection of axons in PNS
White matter
A lot of axons
Tract
Collection of axons in CNS
Bundle
Collection of axons in CNS with differing cell bodies
Capsule
Collection of axons in CNS that connect the cerebrum to the brainstem
Commissure
Collection of axons in CNS that connect the two hemispheres
Lemniscus
Collection of axons in CNS whose tracks meander through brain
Ganglion
Group of cell bodies in the PNS
Nucleus
Group of cell bodies in the CNS
Medial prefrontal cortex functions
Social behaviors, working memory and other executive functions
Limbic system components
Olfactory bulbs, cingulate cortex, amygdala, hippocampus, thalamic nuclei, mamillary body, parahippocampal gyrus
Limbic system function
Mediates emotions, memory, and social behaviors
Hippocampus function
Learning and memory
Amygdala function
Aggressiveness, fear, anxiety, and other emotions
Basal ganglia overall functions
Motor control and procedural learning and memory
Caudate + Putamen =
Striatum; receives input from substantia nigra (DA)
Putamen + Global Pallidus =
Lentiform/lenticular nucleus
Nucleus accumbens location and function
Ventral striatum; reward and addiction
What two arteries does the brain receive blood from?
Internal carotid and vertebral arteries
Internal carotid provides blood to ______ parts of the brain, while the vertebral artery provides blood to the _______ parts of the brain
rostral, caudal
True or false, the blood brain barrier is part of the meninges
No
What crosses the BBB by passive diffusion?
Gases and lipophilic molecules
How do glucose and amino acids cross the BBB?
By facilitated diffusion (can be active, but not always active)
Function of the BBB
Protection of the brain from blood toxins and bacteria
How is the BBB formed?
Tight junctions between the blood vessels and the astrocytes and neurons
Broadmann’s areas are based on _______/________
cytoarchitectural differences/structure
Broadmann Areas 3, 1, 2
Somatosensory
Brodmann’s Area 4
Motor
Brodmann’s Area 17
Vision
Brodmann’s Area 41/42
Auditory
Brodmann’s Area 44/45
Broca’s Area
CT Scan - How
X-ray absorption at several positions around the head
CT Scan - Resolution
Relatively low
CT Scan - Structure or Function?
Structure
CT Scan - Advantages vs Disadvantages
A:
- Cheap
- Simple
D:
- Low spatial resolution
MRI Scan - How
Strong magnets cause protons in brain tissue to line up in parallel, pulse of radio waves alters spin of protons, and protons reconfigure themselves, emitting radio waves that differ by tissue density
MRI Scan - Resolution
Higher than CT
MRI Scan - Structural or Functional
Structural
MRI Scan - Advantages and Disadvantages
A:
- Higher resolution
- Less invasive
D:
- Costly
What is the energy source of the brain?
Glucose
Where does the brain store its energy source?
No where!
fMRI - How
Active neurons demand more glucose and oxygen, so they have greater blood flow to active regions; fMRI measures changes in magnetization between oxygen-rich and oxygen-poor blood; uses BOLD contrast as a measure
True or false: Oxygen poor blood is more magentic
True
True or false: measures of an fMRI are quantitative
False, they are relative
fMRI - Resolution
2-3 mm of active neurons, temporal resolution of a few seconds
How is a mean difference image obtained from fMRI?
Control image is subtracted from the visual stimulus, then participants are averaged
PET - How
Uses radioactive chemicals injected into bloodstream and maps their destination by the radioactive emissions; identifies which brain regions contribute to specific functions
PET - Structural or functional
Functional
True or False: PET scans can identify which brain regions contribute to specific functions
True