Unit 1.2(a) - The Proteome

Question 1

What is the proteome?

Answer 1

The proteome is the entire set of proteins expressed by a geneome

Question 2

What are genes that don’t code for proteins called and what is their purpose?

Answer 2

They are called non-coding RNA genes and include those that are transcribed to produce tRNA, rRNA and RNA molecules that control the expression of other genes

Question 3

What factors affect the set of proteins expressed by a given cell type?

Answer 3

Metabolic activity of cell, cellular stress, the response of signalling molecules and diseased versus healthy cells

Question 4

Why is the proteome larger than the number of genes?

Answer 4

Its larger than the number of genes because more than one protein can be expressed from the same gene due to alternative RNA splicing