UNIT 10 PAIN Flashcards
Pain is:*
what ever the experiencing person says it is existing whenever he says it does
Name the Five Pain Pathways and Processes*
Nociception Transduction Transmission Perception Modulation
What is Nociception*
Normal processing of painful stimli or The ability to feel pain
What is Transduction?*
First injury occurs and release substances that activate nociceptors.
What are Nociceptors?*
Peripheral structures that are specialized receptors in the skin an internal organs that are sensitive to noxious stimuli.
Be specific: Where are Nociceptors found and what are the three types?*
Found in skin , blood vessels, fascia, internal organs, and joints and other structures. Peripheral nerve cells where nociceptors located.
- Thermoreceptors - temp
- Chemoreceptors - chemical
- Mechanical receptors - pressure
First Responder is*
A-Delta - Fibers = Sharp well localized pain
Second Responder is*
C-Fibers = slow responding dull poorly localized and persistent
Bradykinin is a powerful ____ that increases ___ ___ and constricts __ ___.
a powerful vasodilator that increases capillary permeability and constricts smooth muscle
Prostaglandins are important ____-like substances that __ additional ___ stimuli to the ___.
Prostaglandins: important hormone-like substances that send additional pain stimuli to the CNS
Substance P sensitizes ___ on ___ to feel ___ and also ____ the rate of firing of ___.
Substance P: sensitizes receptors on nerves to feel pain and also increases the rate of firing of nerves
Seven Steps of Transmission: Stimuli is transmitted from pain receptors by way to sensory nerves…
Stimuli is transmitted from pain receptors by way to sensory nerves
- into the dorsal root ganglia
- The impulse enters the spinal cord, and synapses terminate in the dorsal horn of the spinal cord
* 3. Substance P a neurotransmitter assists the impulse to cross the cord and ascend up the spinothalamic tract - And areas of the midbrain
- to the thalamus
- where sensation of heat, cold pain and touch identified
- Location and intensity of pain is perceived in the cortex
Specific receptors receive… 3*
Endogenous opiods
Endorphins
Enkephalins
What are Endogenous opioids*
___ and ___ – made by ___ – produce ___ affect by binding to ___ receptors
serotonin and norepinephrine – made by body – produce analgesic affect by binding to opioid receptors
Endorphins*
___ ___ ___ and ___ thought to be released with ___ stimulation (___)
prolonged pain relief and euphoria thought to be released with skin stimulation (massage)
What does Enkephalins* do?
inhibits release of substance P at afferent neurons
What occurs during pain perception?
Spinal reflexes
Muscles near pain site contract
Protective Response
Types of Pain*
- Acute Pain
- Chronic Pain
- Cancer/Malignant Pain
- Persistent Pain / Central Sensitization
- Long Term Central Sensitization
Acute Pain* 1. Cause usually \_\_\_ - follows \_\_\_ \_\_\_ process 2. Intensity usually \_\_\_ with \_\_\_. 3. Is \_\_\_ - \_\_\_ sign 4. May have \_\_\_ signs \_\_\_ and \_\_\_ signs. i.e: increased: \_\_ \_\_\_ \_\_ Facial \_\_\_ & \_\_\_ Lack of _/_ does not mean \_\_\_ pain.
- Cause usually known – follows nociceptive pain process
- Intensity usually decreases with healing
- Is protective - warning sign
- May have observable signs behavioral and physical signs
Increased HR, Resp, b/p
Facial grimacing, guarding,
Lack of s/s does not mean no pain
Chronic Pain*
- What are the 3 characteristic of pain?
- Serves no ___ ___ – may be difficult to___
- ___ pain signaling both ____ or ___.
- ___ and___ – lasts longer than _ to _ mos.
- ___ & ___ pain responses not present
- ___ and ___.
- Persistent, intermittent or limited
- Serves no useful purpose – may be difficult to localize
- Abnormal pain signaling both peripheral or central
- Irreversible and cyclical – lasts longer than 3 to 6 mos
- Physical & behavioral pain responses not present
- Remissions and exacerbations
Cancer / Malignant Pain*
- May be __ __that cause seeking ___.
- Associated with what four things?
- Pain related to what three things?
- Cancer pain has what kind of qualities
- Why may pt not want to report their pain?
- With proper interventions what is possible?
- May be first symptom that cause seeking treatment
- Associated with chemotherapy, radiation, tissue & organ destruction
- Pain related to hormones, neurotransmitters and enzymes
- Cancer pain has acute and persistent qualities
- Reluctant to report since can indicate progression of disease
- With proper interventions may be relieved
Persistent Pain / Central Sensitization
- __ signals bombard ___ and ___ system adaption over time can lead to ___ effects of pain.
- What is it characterized by (give e.x)?*
- What is hyperexcitable?*
- Nerve signals bombard CNS
Nervous system adaptation over time – lead to the detrimental effects of pain - Characterized by enhanced pain to mild noxious stimuli ( rheumatoid arthritis inflammation)
- Light touch causes continuous or very frequent input to CNS = hyperexcitable
Long Term Central Sensitization*
- What is Allodynia?
- What is Hyperglasia
- Allodynia =
abnormal pain signals results in perceived pain with mild, non-painful stimuli
Light touch or blankets on feet = sudden pain - Hyperglasia =
exaggerated response to normal painful stimuli
Lower pain tolerance
Hot liquids on sore throat
Source of Pain: Nociceptive Pain
Name and describe the three types?*
*1. Somatic - originates in the bone, skin and soft tissue. well localized/easy for the patient to point out location. Characterized by throbbing and aching. Example Sprained ankle and metastatic bone pain
*2. Visceral Pain
Originates internally
Due to stretching, distension inflammation or damage to organs
Described as aching, throbbing, cramping, pressure deep or radiating
Pain diffuse and difficult to locate ( MI pain)
- Referred Pain - Pain that originates in one part of the body but perceived in another area