Unit 10

Question 1

Cohesin

Answer 1

• Hold together condensed chromosomes

Question 2

Centromere

Answer 2

• Attached to sister chromosomes before they separate during mitosis

Question 3

Kinetochore

Answer 3

• At centromere
• Attachment point for microtubules

Question 4

Kinetochore microtubules

Answer 4

• Attached to mitotic / condensed chromosomes at the centromeres via kinetochores
• Play critical role in separation of mitotic chromosomes
• Dissassemble but remain attached to chromosomes, pulling chromatids to opposite spindle poles

Question 5

Interpolar microtubules

Answer 5

• Not attached to chromosomes & overlap, are stabilised by proteins called spindle kinesis

Question 6

• Aster microtubules

Answer 6

• Extend outward from centrosomes to cell periphery & have freely exposed (+) ends
• Pulled toward cell periphery by dynein, anchored to plasma membrane. Also pulls spindle poles further apart

Question 7

Spindle kinesins

Answer 7

• Of interpolar microtubules generate a sliding force to push microtubules apart. Forces spindle poles apart