Unit 1 - Tuesday 12 January 2010 Flashcards

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1
Q

Use your knowledge of water potential to explain why these adults get diarrhoea when they drink milk. 2 marks

A
  1. The water potential is lower in the lumen

2. Water enters the lumen from the cells by osmosis

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2
Q

What are the products of lactose being catalysed by lactase? 1 mark

A

Lactose + Water = Glucose and Galactose

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3
Q

What type of reaction includes the addition of water? 1 mark

A

Hydrolysis

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4
Q

Describe how you could use the biuret test to distinguish a solution of the enzyme, lactase from a solution of lactose. 1 mark

A
  • Add biuret solution

- Lactase will turn solution purple as it is an enzyme.

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5
Q

Explain the result you would expect with the enzyme in the biuret test. 1 mark

A

As lactase is an enzyme is reacts as it is a protein.

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6
Q

Describe the path by which oxygen goes from an alveolus to the blood. 2 marks

A
  • Through alveolar epithelium

- Through capillary epithelium/endothelium.

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7
Q

Explain why people with miner’s lung have a lower concentration of oxygen in their blood. 1 mark

A

(Thicker alveolus wall)

- Diffusion pathway is longer

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8
Q

Describe how ventilation helps to maintain this difference in oxygen concentration. 2 marks

A

In the alveolus;

  • Brings in the air containing a high concentration of oxygen.
  • Removes air with a lower oxygen concentration.
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9
Q

Give one other way that helps to maintain the difference in oxygen concentration. 1 mark

A

Circulation of blood

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10
Q

Coal mining in Britain had been dramatically reduced by 1990.
Some scientists concluded that the rise in reported cases of miner’s lung after 1992 shows that the disease takes a long time to develop.
Evaluate this conclusion. 2 marks

A
  • Graph shows fluctuations

- Correlation does not mean causation as other factors may be the reason for miners lung.

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11
Q

Methotrexate is a drug used in the treatment of cancer. It is a competitive inhibitor and affects the enzyme folate reductase.
Explain how the drug lowers the rate of reaction controlled by folate reductase. 2 marks

A
  • Methotrexate has a similar structure to substrate.
  • Binds to the complementary active site.
  • Less E-S complexes can form.
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12
Q

Methotrexate only affects the rate of the reaction controlled by folate reductase. Explain why this drug does not affect other enzymes. 1 mark

A
  • Methotrexate is only similar shape to specific substrate so only fits into this active site.
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13
Q

There are large numbers of mitochondria in this cell. Explain how these organelles help the cell to absorb the products of digestion. 2 marks

A
  • Site of aerobic respiration where ATP is produced.

- Active transport occurs where it goes against the concentration gradient.

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14
Q

Coeliac disease is a disease of the human digestive system. In coeliac disease, microvilli are damaged.
Although people with coeliac disease can digest proteins they have low concentrations of amino acids in their blood.
Explain why they have low concentrations of amino acids in their blood. 2 marks

A
  • Reduced surface area so less absorption.

- Membrane bound enzymes less effective; so proteins not digested.

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15
Q

The students gave their results as a ratio. What is the advantage of giving the results as a ratio? 2 marks

A
  • Allows comparison

- Idea that discs had a different starting mass

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16
Q

The students were advised that they could improve the reliability of their results by taking additional readings at the same concentrations of sodium chloride. Explain how. 2 marks

A
  • Allows anomalies to be identified

- Mean can be produced.

17
Q

The students used a graph of their results to find the sodium chloride solution with the same water potential as the apple tissue. Describe how they did this.
2 marks

A
  • Plot the sodium chloride concentrations onto a graph against ratio and draw a line of best fit.
  • Find sodium chloride concentration from the graph where there is no change is mass.
18
Q

The students were advised that they could improve their graph by taking additional readings. Explain how. 2 marks

A
  • Can plot SD values

- Variability about the mean

19
Q

Other than bacteria, name one type of pathogen. 1 mark

A
  • Fungi

- Virus

20
Q

Give two ways in which a pathogen may cause disease when it has entered the body. 2 marks

A
  1. Produces toxins

2. Damages cells

21
Q

Explain why these antibodies are referred to as monoclonal. 1 mark

A

Antibodies produced from a single clone of B cells/ plasma cells.

22
Q

Tests using monoclonal antibodies are specific (line 7). Use your knowledge of protein structure to explain why. 3 marks

A
  • Specific primary structure/ sequence of amino acids
  • Specific tertiary/ 3D structure
  • Only complementary to one antigen.
23
Q

The tests using monoclonal antibodies allow vets to identify brucellosis while they are still on a farm. Explain the advantages of this. 3 marks

A
  • Rapid treatment of carriers.
  • Isolate infected cattle
  • Infected dairy product not sold
  • Reduces spread of disease
  • Prevent the death of non-infected cattle.
24
Q

The cardiac cycle is controlled by the sinoatrial node (SAN) and the atrioventricular node (AVN). Describe how. 5 marks

A
  • SAN acts as a pacemaker
  • SAN sends waves of electrical impulses across atria causing atrial contraction.
  • AVN delays electrical impulses.
  • Allows atria to empty before ventricles contract.
  • AVN sends electrical impulse down bundle of purikyne fibres.
  • Causing ventricle to contract.
25
Q

What is atheroma and how may it cause myocardial infarction?

A
  1. Cholesterol
  2. In artery wall
  3. Atheroma linked to blood clot
  4. Blocks coronary artery
  5. Reduces oxygen to the heart
  6. Heart unable to respire