unit 1 topic 2 Flashcards

1
Q

define stem cell

A

An unspecialised, immature cell capable of differentiating into a specialised cell

1 Stem cells are unspecialised; that is, they have not yet developed into a particular type of cell.

2 Stem cells have the potential to divide and replicate for long periods of time.

3 Although stem cells are relatively unspecialised cells, they can differentiate to form different specialised cells.

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2
Q

define totipotent cell

A

a stem cell that can develop into any of the types of cells necessary for embryonic development

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3
Q

define pluripotent

A

a stem cell that can develop into many, but not all, of the cell types necessary for foetal development

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4
Q

define potency

A

The ability of a stem cell to differentiate into different cell types

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5
Q

what is the hierarchical structure of tissues organs etc

A
multicellular organisms
systems
organs
tissues
cells
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6
Q

what must a good surface exchange area have

A

◗be moist, because the gases dissolve in water to diffuse from one side of the membrane to the other

◗be thin and permeable, so the gas molecules can move across it easily and quickly

◗have a large surface area in relation to volume of the organism, to adequately supply the gaseous requirements and efficiently remove gaseous waste

◗have a greater concentration of gas to be transported on one side of the membrane than on the other, so that the concentration gradient is maintained

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7
Q

explain the process of respiration in mammals

A

Air passes into the lungs through the nose and mouth and into the trachea (windpipe), which branches into two bronchi (singular: bronchus) leading into the lungs.

Inside the lungs, each bronchus continually divides into smaller tubes called bronchioles, each of which ends in a cluster of tiny air sacs called alveoli.

Inside the lungs, each bronchus continually divides into smaller tubes called bronchioles, each of which ends in a cluster of tiny air sacs called alveoli.

The wall of the capillary, also only one cell thick, surrounds each alveolus.

Gaseous exchange between the two environments occurs naturally by diffusion: there is a higher concentration of oxygen in the air drawn into the alveolus than in the capillaries, and so oxygen enters the capillaries.

conversely, there is a higher concentration of carbon dioxide in the capillaries than in the inhaled air, and so carbon dioxide molecules diffuse out into the alveolus.

the oxygen entering and dioxide leaving moves down a concentration gradient.

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8
Q

define mechanical digestion

A

the physical break down and/or mixing of ingested substances, with no chemical change occurring

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9
Q

explain the process of digestion in mammals

A

Food enters through the mouth, where mechanical digestion first occurs, with the teeth chopping and grinding the food into many smaller pieces.

This physical chewing action creates a much larger surface area of food material upon which the digestive juices, in watery saliva, can better act, in the first stage of chemical digestion.

The tongue carries out the mixing, and moves the food to the back of the throat where it is swallowed into the tubular oesophagus.

The wall of the oesophagus contracts in rhythmic waves to move food into the stomach. Both mechanical and chemical digestion continue in the stomach.

The partially digested food is then released progressively from the stomach into the small intestine, where the bulk and remainder of the chemical digestion takes place to allow passage of nutrients into the body itself.

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10
Q

explain digestion in the small intestine

A

In the small intestine, nutrients such as glucose, amino acids, fatty acids and glycerol move from the gut (digestive tube) into the blood by diffusion and active transport.

The structure of the small intestine is perfect for the uptake of nutrients.

The lining is moist and thin with a rich supply of blood vessels.

Special structures, known as villi project from the surface of the small intestinal tissue.

Villi are tiny finger-like projections, with walls one cell thick. Villi completely cover the inner intestinal surface.

The epithelial cells that form the villi boundaries, in turn, have a cell membrane that is convoluted into multitudes of microvilli. The villi and their microvilli massively increase the surface area of the gut lining and facilitate efficient absorption

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11
Q

define villus

A

an elongated projection from the lining of the small intestine that hugely increases the surface area and thus the capacity for exchange of materials

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12
Q

what are the 4 gas exchange features all exchange surfaces have

A

They are moist

thin

they have a large surface area

and there is a greater concentration of molecules on one side of the exchange surface than on the other.

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13
Q

define proteases

A

breaks down proteins into amino acids

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14
Q

define lipases

A

breaks down lipids into fatty acids and glycerol

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15
Q

describe urea and uric acid

A

In mammals, cells in the liver convert ammonia to the less toxic urea. The urea is carried to the kidneys where it is diluted with water to form urine, which is eliminated from the body.

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16
Q

describe ammonia excretion

A

Ammonia is the simplest of the nitrogenous wastes produced by protein breakdown. It is extremely toxic, so large quantities of water are required to dilute the ammonia and dissolve it for transport out of the body. Fish are totally surrounded by water in their environment, so they can excrete nitrogenous waste in this form.

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17
Q

describe birds and uric acid

A

In a terrestrial environment, where water may be scarce, extra energy is expended by liver cells to very quickly convert ammonia to urea. Urea is much less toxic to cells than ammonia.

Therefore, it can be stored longer in the body and in a more concentrated form, so that less water is lost when it is eliminated.

Birds, reptiles and insects excrete it as uric acid, a whitish semi-solid substance.

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18
Q

define nephron

A

A specialised structural and functional unit within the kidney where elimination of waste molecules from the blood and regulation of solute and water levels occurs

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19
Q

explain how nephrons assist in the kidneys

A

The glomerulus is situated inside the Bowman’s capsule, which looks like a hollow rubber ball that has been pressed in on one side.

The capillaries that form the glomerulus are tightly bound into the smaller Bowman’s capsule, and the blood pumped into them by the renal artery is under very high pressure.

This pressure forces some of the water, along with all its solutes except large proteins and blood cells, out of the blood through the one-cell-thick glomerulus wall and into the Bowman’s capsule, through its one-cell-thick wall.

The liquid in the capsule is referred to as filtrate.

The Bowman’s capsule connects to the proximal tubule, then to a hairpin-shaped loop of Henle, extending down into the medulla, and finally to the distal tubule.

A collecting duct, the last structural component of the individual nephron, collects the filtrate, now containing wastes, from the distal tubule.

The collecting duct passes down through the medulla, and empties the waste filtrate (urine) into an extensive drainage collection system channelling into the kidney’s central cavity (renal pelvis).

From here, urine passes into the ureter, then the bladder and finally into the urethra, which opens to the outside of the body.

Once the filtrate enters the Bowman’s capsule, it becomes part of the external environment.

All of the useful components of the blood that were forced out of circulation into the Bowman’s capsule are not lost to the external environment. The substances left inside the glomerulus capillaries, including the remaining water, then flow on into a branching network of capillaries threading around the nephron’s tubular parts.

Water and solutes required by body cells are reabsorbed from the nephron tubules into the surrounding capillaries, which converge into a branch of the renal vein.

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20
Q

define stoma

A

a controlled opening found in leaves and young stems that controls the movement of gases into and out of a plan

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21
Q

define guard cells

A

a pair of crescent-shaped cells that enable the opening and closing of a stoma

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22
Q

define stomata

A

a stoma is a tiny pore in the surface of a leaf that is used for gas exchange.

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23
Q

define cuticle

A

a thin, transparent layer of wax on the outside of a leaf’s epidermis to reduce water loss

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24
Q

define turgidity

A

the state of being swollen with water, which usually causes the cell to become rigid

25
Q

define palisade mesophyll

A

a densely packed layer of elongated cells that have many chloroplasts for photosynthesis

26
Q

explain what adrenaline does

A

in the adrenal gland

kidney, liver and blood vessels

Constricts blood vessels in kidney and liver; stimulates liver to release more glucose; prepares for ‘fight or flight’ and Prevents excessive immune response

27
Q

define hydrophilic hormone

A

a hormone that is soluble in water and binds to extracellular receptors to initiate a response in that cell; for example, peptide and some amine hormones

28
Q

define hydrophobic hormone

A

a hormone that is insoluble in water and binds to intracellular receptors; for example, steroid and thyroid hormones

29
Q

define brown adipose tissue

A

Brown adipose tissue is richly endowed with blood vessels and mitochondria.

The controlled flow of hydrogen ions in the mitochondria is used to generate heat, instead of adenosine triphosphate (ATP). Hibernating mammals have high levels of brown fat and some mammals also have brown adipose tissue in their neck and between their shoulders. This tissue is specialised for rapid heat production.

Brown adipose tissue is a valuable adaptation that generates heat when babies are cold. The brown adipose tissue gradually reduces with age.

30
Q

define hyperthermia

A

state in which the internal temperature rises above the set point

31
Q

define hypothermia

A

hypothermia: a state in which the internal temperature drops below the set point

32
Q

define endotherm

A

endotherm: an animal that retains heat generated by metabolic activity

33
Q

what are examples of structural mechanisms that help maintain thermoregulation

A

insulation
shape and size
brown adipose tissue

34
Q

define thermoregulation

A

is the process that maintains temperature within a normal range

35
Q

what are examples of behavioural responses that help maintain thermoregulation

A

kleptothermy (huddlung)
torpor (decreased physical activity)
aestivation (avoiding damage from high temps)
hibernation (avoiding damage from low temps)

36
Q

what are examples of physiological mechanisms that help maintain thermoregulation

A

vasomotor control (vasodilation vs vasoconstriction)
evaporative heat loss (sweating)
counter current heat exchange (saving energy via opposite directions of blood)
thermogenesis (shivering)

37
Q

what are examples of homeostatic mechanisms that help maintain thermoregulation

A

hypothalamus
thyroid hormones
insulin/glucagon

38
Q

define non-infectious diseases

A

Non-infectious diseases are not caused by pathogens and are not communicable – they cannot be transmitted from one individual to another.

These include nutritional diseases, such as obesity, malnutrition and beri beri, and degenerative diseases, such as diabetes, osteoporosis and Alzheimer’s disease.

Factors in the environment may also cause disease. Intake of heavy metal particles such as lead interferes with the development of the nervous system, and overexposure to sunlight can trigger skin cancer.

39
Q

define infectious diseases

A

a disease caused by a pathogen that can be transmitted from one organism to another.

40
Q

define incubation period

A

the time between infection and the onset of symptoms

41
Q

define virus

A

a non-cellular pathogenic agent with either DNA or RNA that can only reproduce inside a living host cell

42
Q

define resistance

A

the extent to which an organism is or is not affected by an agent such as a pathogen or chemical toxin

43
Q

define lysis

A

the process of a cell bursting

44
Q

define prion

A

small infectious protein

brings about the degeneration of the nervous system

Prions are unique among pathogenic agents because they do not possess any genetic material, neither DNA nor RNA. They are much smaller than even viruses.

The prion protein is very resistant to high temperatures, strong enzymes and ultraviolet radiation, and there is no effective treatment. The prion form of the protein can arise spontaneously, but it is usually transmitted by entering the body in infected food, most commonly brain tissue from an infected animal

45
Q

define bacteria

A

They have a cell wall outside their cell membrane.

Some species have an outer protective capsule; others have a whip-like flagellum for movement. Many bacteria can form tough, dormant structures called endospores, which are resistant to extreme temperatures, chemicals and drying out.

An endospore consists of a bacterium’s DNA, ribosomes and other cytoplasmic substances. This adaptation helps bacteria withstand unfavourable conditions and facilitates dispersal to new hosts

46
Q

define endospore

A

a tough, dormant structure formed by many bacteria to help them resist unfavourable conditions and disperse to new hosts

47
Q

define flagellum

A

a whip-like appendage that helps bacteria move

48
Q

define capsule

A

a slimy layer sitting outside the cell wall of some species of bacteria

49
Q

what is an example of a disease caused by bacteria

A

Tetnus

Sustained, severe muscle contractions due to blocking of nerve impulses by tetanus toxin

50
Q

what shapes can bacteria be

A

spherical, known as coccus (plural: cocci)
rod-shaped bacillus (plural: bacilli)
spiral (plural: spirilli)
vibrio, rather like a comma

51
Q

define fungi

A

Fungi include large organisms, such as mushrooms and toadstools, as well as minute forms that can only be seen under a microscope.

Microscopic fungi include unicellular yeasts and moulds. Fungi are eukaryotes that reproduce by spores and have cell walls made of chitin, rather than cellulose.

Most fungal diseases in animals are external, where they irritate and inflame the skin. A common example is ringworm, a fungal skin infection of rabbits, dogs, cats, horses and humans

52
Q

define protist

A

Protists are unicellular, eukaryotic organisms. They reproduce both sexually and asexually.

This includes Giardia and Cryptosporidium, both of which produce symptoms of fatigue, nausea and diarrhoea.

These two species also produce environmentally resistant cyst stages that are passed in the faeces of a host and transmitted to a new host in drinking water. Amoebic dysentery is also caused by pathogenic protists transmitted in contaminated water

53
Q

define parasites

A

A parasite is an organism that lives on or in its host for all or part of its life, causing harm and gaining nutrition from the host. Because parasitism is a relationship between organisms in which one organism, the parasite, benefits at the expense of the other organism, the host, by definition all parasites are pathogens

54
Q

define endoparasite

A

a parasite that lives inside another parasite

55
Q

define ectoparasite

A

a parasite that lives on the surface of another organism

56
Q

define definitive host

A

a host in which the adult phase of a parasite produces gametes

57
Q

define intermediate host

A

an organism in which a pathogen or parasite undergoes development and spends a small portion of its life cycle

58
Q

define adherence factor

A

a characteristic that helps bacteria to invade the host, cause disease and evade host defences