Unit 1 KA-1 Flashcards

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1
Q

What is a Stem Cell?

A

Unspecialised cell that can divide and the differentiate into any cell type

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2
Q

What is a multi-potent stem cell?

A

Stem cells that have the potential to make ALMOST all types of cell types found within a particular tissue.

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3
Q

Define pluripotent.

A

Pluripotent cells are embryonic stem cells that can divide/differentiate into ALL cell types

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4
Q

What is a Tumour?

A

A Tumour is a mass of cancer cells produced by excessive uncontrolled cell division.

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5
Q

Define Diploid and haploid.

A

Diploid refers to a cell having 2 sets of chromosomes
Haploid is when a cell has only 1 set of chromosomes.

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6
Q

What is a Germline cell?

A

A lineage of cells that include gametes (any sex cell) and that maintain the cells to produce gametes.

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7
Q

What is epithelial tissue made up of?

A

Epithelial cells which form the lining of the tissue of the body inside and out.

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8
Q

Give an definition of somatic cells.

A

Somatic cells are diploid and divide during growth and repair to increase and maintain total cell numbers.

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9
Q

What do somatic cells divide by?

A

Mitosis, to maintain the diploid chromosome number.

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10
Q

What to Germline cells divide by?

A

When producing more germline cells they divide by MITOSIS and when the nucleus divides to make haploid gametes (sex cells) it divides by MEIOSIS.

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11
Q

Why is the maintenance of chromosome complement important?

A

To ensure that no genetic information is lost or duplicated.

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12
Q

Define Meiosis.

A

Meiosis is a type of cell division that can only take place in the nucleus of a germline cell resulting in four haploid gametes.

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13
Q

Define Mitosis

A

Division of the nucleus of either somatic or germline cells giving two diploid daughter cells.

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14
Q

Define differentiation

A

Differentiation is the process by which a cell expresses certain genes to produce proteins characteristic for that type of cell

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15
Q

Identifying features of an Embryonic stem cell

A

Found in early embryo (blastocyst)
Pluripotent - can differentiate into all cell types
All genes can be switched on/off
Ethical concerns as use involves destruction of embryo

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16
Q

Identifying features of Tissue Stem Cell

A

Found in adult tissue
Multi-potent - Can differentiate into almost all types of cell
Not all genes can be switched on/off
Does not involve destruction of embryo

17
Q

What uses do stem cells have?

A

Corneal repair, regeneration of damaged skin & treatment of Parkinson’s Disease, Diabetes and Alzheimer’s.