Unit 1 - Chps. 1, 5-7, and 23 Flashcards
UNT BIOL 3800, Dr. Welch
List the three chemical classes of hormones and provide an example of each
A. Peptide Hormone (ex. insulin, HGH, glucagon)
B. Steroid (ex. estrogen, testosterone, cortisol)
C. Amino acid (ex. Dopamine, catecholamine, epiniphrine)
How are peptide hormones synthsized and stored?
Made in advance, stored in secretory vesicles
How are steroid hormones synthesized and stored?
Made on demand, cannot be stored since lipid-soluble
How are peptide hormones released from parent cells?
Through exocytosis
How are steroid hormones released from parent cells?
Through simple diffusion
Where are the receptors for peptide hormones?
On the cell membrane
Where are the receptors for steroid hormones?
In the cytoplasm or nucleus
How are amino acid hormones synthesized and stored?
Made in advance, stored in secretory vesicles.
How are amino acid hormones released from parent cells?
Catecholamines - through exocytosis
Thyroid hormones - through transport proteins
Where are the receptors for catecholamine amino acid hormones?
On the cell membrane
Where are the receptors for thyroid (amino acid) hormones?
On the promoter region of DNA
How are peptide hormones transported through the blood?
They are dissolved in plasma
How are catecholamine hormones transported through the blood?
They are dissolved in plasma
How are thryoid hormones transported through the blood?
They are bound to carrier proteins
How are steroid hormones transported through the blood?
They are bound to carrier proteins
What is the half-life of a peptide hormone?
Short half-life
What is the half-life of a catecholamine hormone?
Short half-life
What is the half-life of a thyroid hormone?
Long half-life
What is the half-life of a steroid hormone?
Long half-life
What is the receptor type and action for peptide hormones?
Activation of second messengers through GPCR and IP3 pathway
What is the receptor type and action for catecholamine hormones?
Activation of second messengers
What is the receptor type and action for thyroid hormones?
Activation of gene transcription and translation
What is the receptor type and action for steroid hormones?
Activation of gene transcription and translation; may have nongenomic actions
What is the general target response for peptide hormones?
Modify existing proteins and induce new protein synthesis