Unit 1 Flashcards
What is Immunity?
The body’s natural or induced response to fight infection and its associated conditions.
What is immunity?
The body’s natural or induced response to fight infection and its associated conditions.
What is inflammation?
a nonspecific response of the immune system.
What are the normal ranges of Leukocytes?
4,500-10,000
What is leukocytosis?
WBC count greater than 10,000
What are the primary cells involved in immune response?
Granulocytes and Monocytes
What are the primary cells involved in immune response?
Granulocytes and Monocytes
What are the functions of Eosinophils?
Phagocytosis, Protection against parasites and they are involved in allergic responses.
What are the functions of Basophils?
to release chemotactic substances
What are the functions of Monocytes and Macrophages?
Functions are trapping and phagocytosis of foreign substances and cellular debris.
What are the functions of T Cells?
function to control viral infections and destruction of cancer cell. involved in hypersensitivity reaction and graft tissue reaction.
What are the functions of B Cells?
Functions to produce antibodies (immunoglobulins) to specific antigens.
What are the functions of Natural Killer Cells?
Functions are cytotoxicity, killing tumor cells, fungi, viral infected cells, and foreign tissue.
What are the functions of Lymphoid Structures?
Site of activation of immune cells by antigens.
What are Basophils?
Not phagocytic, contains proteins and chemicals such as heparin, histamine, bradykinin, serotonin, and leukotrienes, released during hypersensitivity.
What are Basophils?
Not phagocytic, contains proteins and chemicals such as heparin, histamine, bradykinin, serotonin, and leukotrienes, released during hypersensitivity.
What are Monocytes?
Largest Leukocyte, Activates against chronic infections such as TB, Viral infections, intracellular parasitic infections.
What are Eosinophils?
Found in the respiratory or GI tract. Phagocytic. Less efficient than neutrophils, protect body from parasitic worms.
What is chemotaxis?
Monocytes mature into Macrophages that are drawn to inflamed area by chemicals released.
What are the five classes of immunoglobulins?
IgG, IgM, IgA, IgA, IgD
What is the immunoglobulin IgM function?
Produced 48-72 hrs after antigen enters body. responsible for primary immunity. produces antibodies against rheumatoid factors, gram negative organisms, and ABO group. does not cross placental barrier. low in newborns, increases by nine months.
What is the immunoglobulin IgG function?
results from secondary exposure to foreign antigen. responsible for antiviral and antibacterial activity. crosses placental barrier. response is stronger and longer than others.
What is the immunoglobulin IgA function?
found in secretions of respiratory system, GI, tears, and saliva. protects mucous membrane invading organisms. does not cross placental barrier. Congenital IgA deficiency makes one prone to autoimmune disease.
What is the immunoglobulin IgE function?
increases during allergic reactions and anaphylaxis.
What is the immunoglobulin IgE function?
increases during allergic reactions and anaphylaxis.
What is the function of lymph nodes?
Filter antigens and foreign products from lymph, support and house proliferation of lymphocytes and macrophages.
What are the two kinds of tissues in the spleen?
White pulp and Red pulp
What is the function of the white pulp in the spleen?
B cells predominate site for lymphocyte proliferation and immune surveillance.
What is the function of the red pulp in the spleen?
Phagocytic cells and damaged/aged RBC stored for future use.
What happens if the spleen is damages?
The liver and bone marrow takes place of its functions.
What are the normal flora of the skin?
staph epidermis, staph aureus, corynebacterium xerosis, micrococcus luteus.
What is the normal flora of the nasal passages?
staph aureus and staph epidermis
What is the normal flora of the oropharynx?
streptococcus pnuemonieae, strep sallivarus, Neisseria meningitis.
What is the normal flora of the intestines?
staph aureus, bacteriodes, bifidobacterium, eubacterium, clostridium, lactobacillus, and e. coli
What is the normal flora of the mouth?
Strep mutans, strep mitis, lactobacillus, actinomyces, and spirochetes
What is the normal flora of the mouth?
Strep mutans, strep mitis, lactobacillus, actinomyces, and spirochetes
What is communicable disease?
an illness that is directly transmitted from one individual or animal to another by contact with body fluids or indirect contact transmitted by contaminated objects.
What is infectious disease?
a communicable disease that is caused by microorganisms that are commonly transmitted from an individual or animal to another.
What is pathogenicity?
pathogens ability to produce disease
What is pathogenicity?
pathogens ability to produce disease
What is medical asepsis?
includes all practices intended to confine a specific microorganism to a specific area thus limiting the number of growth and transmission of microorganisms.
What is sepsis?
the whole body inflammatory process resulting in acute illness however the term is often used generally to refer to the state of infection
What is bacteria?
the most common infection causing microorganism
What is parasites?
microorganisms that live on other organisms?
What is parasites?
microorganisms that live on other organisms?
What is colonization?
the process by which strains of microorganisms become resident flora. microorganisms may grown and multiply but they do not cause disease.
What is a systemic infection?
an infection that is widespread and affects many different areas of the body.
What are Healthcare Associated Infections (HAI’s)?
nosocomial infections or hospital acquired infections.
What are Healthcare Associated Infections (HAI’s)?
nosocomial infections or hospital acquired infections.
What is the chain of infection?
- Infectious agent- pathogen (etiologic agent)
- Reservoir- where they live, multiply (living and nonliving)
- Portal of Exit- bodily fluids, sneezing, cough, wounds.
- Method of Transmission- Direct, Indirect, Airborne
- Portal of Entry- mouth, nose, genitalia, wounds.
- Susceptible Host- someone at risk for infection
What is a primary infection?
The first time you infected by a specific migroorganism, ex. chickenpox
What is a primary infection?
The first time infected, ex. chickenpox
What is a secondary infection?
The second time you are infected by a specific microorganism, ex. shingles
What are some risk factors of infection?
Age, babies and elderly have weaker immune systems.
Health Status- one already having health issues are more susceptible
Lifestyle- Smokers, poor nutrition, etc
Environment- Works at places with lots of infections around, ex. hospital
What is an acute infection?
an infection with a sudden onset (common cold)
What is a chronic infection?
an infection with a longer duration (fungal infection)
What is a latent infection?
an infection with a period of no symptoms (TB, HIV, Herpes)
What is indirect transmission of infection?
Microorganism is transferred by other means. Vehicle-borne (fomite on inanimate object) or vector-borne (animal or insect bite) or airborne (droplet or dust)
What is indirect transmission of infection?
Microorganism is transferred by other means. Vehicle-borne (fomite on inanimate object) or vector-borne (animal or insect bite) or airborne (droplet or dust)
What are the stages of infection?
incubation, prodromal, illness, decline, and convalescence.
When is the incubation stage of infection?
time of infection to symptoms showing
When is the prodromal stage of infection?
when there is an appearance of mild symptoms (short time)
When is the illness stage of infection?
signs and symptoms most evident