Unit 1 Flashcards
Erythrocyte lifespan/amount of cells produced per day
120 days/ 2.5E9 cells per kg body weight per day
Platelet lifespan/amount of cells produced per day
7 days/2.5E9 cells per kg body weight per day
Neutrophil lifespan/amount of cells produced per day
7 hours/1.0E9 cells per kg body weight per day
CFU-G
Colony Forming Unit for Granulocytes
CFU-E
Colony Forming Unit for Erythrocytes
CFU-M
Colony Forming Unit for Monocytes
CFU-Meg
Colony Forming Unit for Megakaryocytes
CFU-Eo
Colony Forming Unit for Eosinophils
CFU-Baso
Colony Forming Unit for Basophils
CFU-L
Colony Forming Unit for Lymphoid cells, Pluripotent Stem Cell, mother of all lymphoid cells
CFU-LM
Colony Forming Unit for Lymphoid and Myeloid Cells, Multipotent stem cell
CFU-GEMM
Colony Forming Unit for granulocytes, erythrocytes, monocytes, and megakaryocytes. Pluripotent Stem Cell, mother of all myeloid cells
CFU-GM
Colony Forming Unit for Granulocytes and Macrophages
GM-CSF
“Granulocyte-Macrophage Colony Stimulating Factor”. Is a multilineage growth factor for stimulating hematopoiesis
IL-3
Interleukin 3. Is a multilineage growth factor for stimulating hematopoiesis
G-CSF
“Granulocyte-Colony Stimulating Factor”. Stimulates CFU-G
M-CSF
“Macrophage-Colony Stimulating Factor”. Stimulates CFU-M
Erythropoietin (Epo)
Stimulates erythropoiesis, stimulates CFU-E, BFU-E.
BFU-E
Burst Forming Unit-Erythroid. This is the progenitor to CFU-E.
DCYTB
Duodenal Cytochrome B like Protein. Reduces Fe3+ to Fe2+ so that it can enter the duodenal epithelial cells
DMT1
Divalent Metal Transporter. Allows Fe2+ to enter the duodenal epithelial cells
Ferroportin
Allows iron atoms to leave the duodenal epithelium on the basolateral side
Haephestin
Possibly oxidizes Fe2+ into Fe3+ on the basolateral side of the duodenal epithelium, so that the Fe3+ can bind to plasma apotransferrin