Unit 1 Flashcards
Pharmacokinetic Phase
- Delivery and removal.
- absorption
- Metabolism
- Distribution
- Excretion
Pharmacology
- Safety
- Nursing Process
- Education
- Make sure you’re advocating for your patient
- The study of drugs that alter functions of living
organisms.
Aspirin
Thin your blood
Risk for bleed
Never for kids
Major problem with elderly
Heart
Pharmaceutic Phase
- Pill disintegrates into particles to cross the biologic membrane.
- Particles -> dissolution and prep for G.I. tract into bloodstream
Absorption
GI tract to blood by passive absorption, active absorption, or pinocytosis.
Distribution
Delivery to site of action (May be affected by half-life of the drug size of dose, blood flow, etc.)
Metabolism
- Biotransformation
* Inactivation
Elimination
- Kidneys !
- Removal from the body; changes in kidneys can reduce elimination,
causing accumulation of the drug in turn becoming toxic, - cretin clearance best indicator of kidney function
Digoxin
Anything greater than 2.5 bradycardia and hypertension.
Agonist
Do more of something
Antagonist
Do less of something
Brand name: Bactrim
What is the generic name?
Trimethoprim sulfamethoxazole
Alpha 1 receptors are located ?
In blood vessels, eye, bladder, and prostate.
A2 receptors are located where ?
Postganglionic sympathetic nerve endings
Barbiturates are for short or long term ?
Short term not long term
Reyes Syndrome
- Fatty build up around the liver.
- Fatal
- Ages between 4-16
- Kids if they get a viral infection
Excretion organ
Kidneys