Unit 1 Flashcards
Atherosclerosis
This heart disease is caused by deposits of cholesterol and other substances on the arterial walls, which form plaques that narrow the arteries. Tissue damage occurs when the presence of atherosclerotic plaques reduces the flow of blood through the arteries and interferes with the passage of nutrients from the capillaries into the cells. Poor health habits such as smoking and a high-fat diet have led to two primary clinical manifestations associated with atherosclerosis:
o Angina pectoris, or chest pain, occurs because the muscle tissue of the hear must continue its activity without a sufficient supply of oxygen or adequate removal of carbon dioxide and other waste products.
o Myocardial infarction is most likely to occur when a clot has developed in a coronary vessel and blocks the flow of blood to the heart. A myocardial infarction, also known as a heart attack, can cause death.
Arteriosclerosis
a vessel disorder that hardens the arteries, and results when calcium, slats, and scar tissue react with the elastic tissue of the arteries. The consequence is to decrease the elasticity of the arteries, making them rigid and hard. Blood pressure then increases because the arteries cannot dilate and constrict to help blood move, and hypertension (high blood pressure) may result.
Phlebitis
a disorder that produces inflammation of a vein wall, often accompanied by water retention and pain. The condition typically results from an infection surrounding the vein, from varicose veins, from pregnancy-related bodily changes, or from the pressure of a tumor on the vein. The chief threat posed by phlebitis is that it can encourage the production of blood clots, which then block circulation.
Varicose veins
are superficial veins that have become dilated or swollen. Typically, veins in the lower extremities of the body are most susceptible because they are subjected to great pressure from the force of gravity.
Rheumatic Fever
a bacterial infection that originated in the connective tissue and can spread to the heart, potentially affecting the functioning of the heart valves. The flaps of the valves may be changed into rigid, thickened structures that interfere with the flow of blood between the atrium and the ventricle. People with rheumatic fever, or with congenital heart disease, are particularly vulnerable to endocarditis, the inflammation of the membrane that lines the cavities of the heart, which is caused by staphylococcus or streptococcus organisms.
anemia
a condition in which the number of red blood cells or amount of hemoglobin is below normal. Through loss of blood, much vital iron (essential for the production of hemoglobin) is lost. Iron supplements must sometimes be taken to offset this problem. Other forms of anemia, including aplastic anemia, may occur because the bone marrow is unable to produce a sufficient number of red blood cells. The result if a decrease in the blood’s transport capabilities, causing tissues to receive too little oxygen and to be left with to much carbon dioxide.
erythrocytosis
a disorder characterized by an excess of red blood cells. It may result from a lack of oxygen in the tissues or as a secondary manifestation of other diseases. It also increases the viscosity of the blood and reduces the rate of blood flow.
sickle-cell anemia
a disease related to red blood cell production. A genetically transmitted inability to produce normal red blood cells. These cells are sickle-shaped instead of flattened spheres, and they contain abnormal hemoglobin
hemophilia
a clotting dysfunction that affects individuals who are unable to produce thromboplastin and fibrin. Therefore, their blood cannot clot naturally in response to injury, and they may bleed to death unless they receive medication.
Distinguish between humoral and cell-mediated immunity.
Humoral immunity is mediated by B lymphocytes (produced in bone marrow), which protect against bacteria, neutralizing toxins produced by bacteria, and preventing viral re-infection. B cells confer immunity by the production and secretion of antibodies, which are the basis of the antigen-specific reactions.
Cell-mediated immunity involves T lymphocytes (produced in thymus gland) and is a slower acting response. Rather than releasing antibodies into the blood, as humoral immunity does, cell-mediated immunity operates at the cellular level. When stimulated by the appropriate antigen, T cells secrete chemical agents that kill invading organisms and infected cells.
epilepsy
• Epilepsy is a disease of the central nervous system affecting more than 3 million people in the United States. It is often idiopathic, which means that no specific cause for the symptoms can be identified. Symptomatic epilepsy may be traced to injury during birth; severe injury to the head, infectious disease, or metabolic or nutritional disorders. Epilepsy is marked by seizures, which range from barely noticeable staring or purposeless motor movements to violent convulsions accompanied by irregular breathing, drooling, and loss of consciousness. Epilepsy cannot be cured, but it can often be successfully controlled through medication and behavioral interventions.
cerebral palsy
• Cerebral palsy is a chronic, non-progressive disorder marked by lack of muscle control. It stems from brain damage caused by an interruption in the brain’s oxygen supply, usually during childbirth. In older children, a severe accident or physical abuse can produce the condition. Sufferers may also have seizures, spasms, mental retardation, difficulties of sensation and perception, and problems with sight, hearing, or speech.
Parkinson’s
• Parkinson’s disease is marked by progressive degeneration of the basal ganglia, the group of nuclei that controls smooth motor coordination. The result of this deterioration is tremors, rigidity, and slowness of movement. Although the cause of Parkinson’s disease is not fully known, depletion of the neurotransmitter dopamine may be involved. Patients may be treated with medication, but massive doses, which can cause undesirable effects, are often required for control of the symptoms.
multiple sclerosis
• Multiple sclerosis is a degenerative disease of certain brain tissues can cause paralysis and, occasionally, blindness, deafness, and mental deterioration. Early symptoms include numbness, double vision, dragging of the feet, loss of bladder or bowel control, speech difficulties, and extreme fatigue. The effects of the disorder result from the disintegration of myelin, a fatty membrane that surrounds the nerve fibers and facilitates the conduction of nerve impulses. Multiple sclerosis is an autoimmune disorder, so-called because the immune system fails to recognize its own tissue and attacks the myelin sheath surrounding nerves.
Huntington’s disease
• Huntington’s disease is a hereditary disorder of the central nervous system, and characterized by chronic physical and mental deterioration. Symptoms include involuntary muscle spasms, loss of motor abilities, personality changes, and other signs of mental disintegration. Because some of the symptoms are similar to those of epilepsy, Huntington’s disease is sometimes mistaken for epilepsy.
polio
Polio or (poliomyelitis) is viral disease that attacks the spinal nerves and destroys the cell bodies of motor neurons so that motor impulses cannot be carried from the spinal cord outward to the peripheral nerves or muscles. Depending on the degree of damage that is done, the individual may be left with difficulties of walking and moving properly, ranging from shrunken and ineffective limbs to full paralysis.
Two types of paralysis
• Two types of paralysis: Paraplegia is paralysis of the lower extremities of the body; which results from an injury to the lower portion of the spinal cord. Quadriplegia is paralysis of all four extremities and the trunk of the body; it occurs when the upper portion of the spinal cord is severed. Once the spinal cord has been severed, no motor impulses can descend to tissues below that cut nor can sensory impulses from the tissues below the cut ascend to the brain. As a consequence, a person usually loses bladder and bowel control. Moreover, the muscles below the cut area may well lose their tone, becoming weak and flaccid.
Discuss the course of treatment for anorexia nervosa and bulimia.
Anorexia: Initially, the chief target of therapy is to bring the patient’s weight back up to a safe level, a goal that must often be undertaken in a residential treatment setting, such as a hospital. To achieve weight gain, most therapies use cognitive behavioral approaches. With anorexics, motivational issues are especially important. That is, inducing the anorexic to want to change her behavior and to adapt an active, collaborative to regaining weight and changing behavior is essential. Family therapy may be initiated to help families learn positive methods of communicating emotion and conflict. Therapeutic goals also include improving self-esteem and teaching coping skills for stress and social pressure.
Bulimia: Therapeutic approaches focus on self-monitoring of eating behavior; increasing the regularity of meals; encouraging the client to eat a greater variety of food; delaying the impulse to purge; breaking the association between eating and purging; building self-efficacy with respect to eating; identifying situations that lead to binge eating and developing other coping skills; and relaxation and stress management.
Compare the four ways in which microbes are transmitted to people.
- Direct transmission: Involves bodily contact, such as handshaking, kissing, and sexual intercourse. For example, genital herpes is generally contracted by direct transmission.
- Indirect transmission: This kind occurs when microbes are passed to an individual via airborne particles, dust water, soil, or food. Influenza is an example of environmentally transmitted disease.
- Biological transmission: Biological transmission occurs when a transmitting agent, such as a mosquito, picks up microbes, changes them into a form conducive to growth in the human body, and passes on the disease to the human. The transmission of yellow fever, for example, occurs by this method.
- Mechanical transmission: This is the passage of a microbe to an individual by means of a carrier that is not directly involved in the disease process. Transmission of an infection by dirty hands, bad water, rats, mice, or flies are methods of mechanical transmission. Although mechanical and biological transmission are similar in that an organism such as an insect can be a transmitting agent, mechanical transmission differs in that the microbe is carried on the surface of the transmitting agent (e.g., a fly) as opposed to inside of the agent (e.g., a mosquito).
obesity
An excessive accumulation of body fat, believed to contribute to a variety of health disorders, including cardiovascular disease.
yo-yo dieting
The process of chronically alternative between dieting and regular eating, leading to successive weight gains and losses; over time, yo-yo dieters increase their chances of becoming obese by altering their underlying metabolism.
set point of theory weight
The concept that each individual has an ideal biological weight that cannot be greatly modified.
divisions of the nervous system: The peripheral nervous system is, itself, made up of two main components:
a. The somatic (or voluntary) nervous system connects nerve fibers to voluntary muscles and provides the brain with feedback in the form of sensory information about voluntary movement.
b. The autonomic (or involuntary) nervous system connects the central nervous system with all internal organs over which people do not customarily have control. This system can be divided into two distinct subsystems:
i. The sympathetic nervous system which prepares the body to respond to emergencies; to strong emotions, such as anger and fear, and to strenuous activity.
ii. The parasympathetic nervous system controls the activities of organs under normal circumstances and helps restore the body to a normal state.
the central nervous system consists of
brain and spinal cord
stomach
The stomach produces various gastric secretions, including pepsin and hydrochloric acid to further the digestive process, once the food passes through the esophagus by means of peristalsis, a unidirectional muscular movement toward the stomach.
pancreas
As food progresses from the stomach to the duodenum (the intersection of the stomach and lower intestine), the pancreas becomes involved in the digestive process. Pancreatic juices, which are secreted into the duodenum, contain several enzymes that break down proteins, carbohydrates, and fats. A critical function of the pancreas is the production of the hormone insulin, which facilitates the entry of glucose into the bodily tissues.
liver
The liver also plays an important role in metabolism by producing bile, which enters the duodenum and helps break down fats. Bile is stored in the gallbladder and is secreted into the duodenum as needed.
small intestine
The absorption of food takes place primarily in the small intestine, which produces enzymes that complete the breakdown of proteins to amino acids. The motility of the small intestine is under the control of the sympathetic and parasympathetic nervous systems, such that parasympathetic activity speeds up metabolism, whereas sympathetic nervous system activity reduces it.
large intestine
Food then passes into the large intestine (whose successive segments are known as the cecum and the ascending, transverse, descending, and sigmoid colon), which acts largely as a storage organ for the accumulation of food residue and helps in the reabsorption of water. The entry of feces into the rectum then brings about the urge to defecate, or expel, the solid waste from the body via the anus.
Discuss the role of the spleen, tonsils and thymus gland in immunity.
- The spleen aids in the production of B cells and T cells and removes old red blood cells from the body. It also helps filter bacteria and is responsible for the storage and release of blood.
- The tonsils are patches of lymphoid tissue in the pharynx that filter out microorganisms that enter the respiratory tract.
- The thymus gland is responsible for helping T cells mature; it also produces a hormone, thymosin, which appears to stimulate T cells and lymph nodes to produce the plasma cells that, in turn, produce antibodies.