Unit 1 Flashcards
Micro-organisms
Can also be called a microbe, includes fungi and bacteria, includes viruses even though they are considered “non-living”
- not all micro-organisms are bad - yeast for beer, bacteria for cheese
- can be single or multi-called
Micro-organisms that cause illness …
Pathogenic
Bacteria
Living organism, unicellular, can cause disease, localized infections, treatment - antibiotics, and reproduces through fission - form of asexual reproduction
Viruses
Opinions differ on whether viruses are a form of life, or organic structures that interact with living organisms, no cells (not living), can cause disease, infections are systemic, treatment - vaccines prevent the spread of infection and anti-viral medications help to slow re-education but cannot stop it completely, reproduces invades a host cell and takes over the cell causing it to make copies of the viral DNA / RNA, destroys the host cell releasing new viruses
How to name bacteria based on their shape
Cocci - oval
Bacilli - rod
Spiral
Other - square, star, spindle
Naming bacteria based on gram staining
Gram negative - thin
Gram positive - thick
Broad spectrum antibiotics can be used for both types of bacteria
Staphylococcus aureus bacteria
Gram positive, round shaped bacterium, usually found in the upper respiratory tract and on the skin, causes variety of clinical diseases
Proliferation of antibiotic resistance strains of bacteria
Bacteria becoming immune to the effects of drugs, occurring because of abuse of antibiotics (banana flavoured penicillin), over prescription, unfinished course of treatments, food additives
Example - methicillin resistant staphylococcus aureus (MRSA)
Recurrence of disease thought to be under control or eradicated
Pertussis making a come back, tuberculosis (higher risk for indigenous and immigrants from endemic countries)
Source
Something that is contaminated with, or carries an infectious agent (blood covered gloves for example)
Reservoir
A place in which organisms can live and multiply
- Typhoid Mary (cook with salmonella thypi)
- ambulance equipment
Incubation period
The time between contact with an infectious agent and the presence of symptoms - can be long or short, HIV incubation period can be 7-10 years or Ebola virus - hours
- during the incubation period the host may or may not be infectious to others (contagious)
Communicable period
The time during which a person can transmit an infectious disease to others
- chicken pox communicable period is from approximately 2 days before the lesions break out until the lesions are crusted over
Exposure
Coming into contact with an infectious agent, having been exposed does not mean that you will become infected
Type of exposure needed to transmit disease varies depending on the infectious agent …
- chicken pox is highly contagious and you can become infected by being in the same room with a person in their communicable period
- HIV not highly contagious, need significant levels of direct exposure of contaminated body fluids with blood or mucous membranes
Physical barrier to infection
Intact skin - organisms cannot enter intact skin, body’s main dense against infection
Ciliary activity in mucous membranes (lungs)
Chemical barriers to infection
Acidic pH of the skin has inhibitory effect on bacteria, normal flora (the good bugs) keeps infection from invading organisms
Immune system as an infection barrier
Immune system - phagocytes - antibodies
- an intact immune system is also crucial to warding off infection
Immunity as infection barrier
Functions of the immune system, protects against disease or damaging foreign bodies, we get it from our moms, previous exposure or vaccines
Increasing ability of immune system to fight infection
- infant’s get immunity from mother’s blood and from breast feeding
- recent study compared infants that were born vaginally vs by cesarean section and found their gastrointestinal flora was different
Vaccination
Unable to cure many diseases but we can be vaccinated, vaccination is a means of priming the immune system so that it will quickly recognize an infectious agent and launch a response against it
- achieved by exposing the body to micro-organisms that are weakened or altered so that the vaccine will not give you the disease but will cause the immune system to mount a response
- response measured by antibody titer
Immunoglobulin
Also called antibodies, secreted by WBC in response to an antigen, binds to antigen and neutralizes it, short lasting immunity can be achieved by giving a person actual antibodies, the injected antibodies rather than the person’s own antibodies fight the disease
Direct contact
Direct physical contact between an infected individual and a host
Indirect contact
Person becomes infected through contact with contaminated object
Vector transmission
Disease is spread to host by a carrier, usually an animal or insect (mosquito, deer tick)
Airborne transmission
Transmission by droplet nuclei (residue of evaporated droplets) or by contaminated dust particles that remain suspended in the air for a long time, close contact not necessary
- airborne - spread happens when a germ floats through the air after a person talks, coughs or sneezes, airborne spread diseases includes - chickenpox, tuberculosis
- droplet - spread happens when germs travelling inside droplets are coughed or sneezed from a sick person enters the eyes, nose, or mouth of another person
Hepatitis
Inflammation of the liver causing jaundice, anorexia, nausea and vomiting, malaise (general feeling of ill), dark urine, caused by a virus
Hepatitis A
- transmitted by the fecal - oral route (ingestion of food or water that has been contaminated by infected feces)
- incubation period of approximately four weeks
- illness starts abruptly and lasts for 1-2 weeks but it will take some time before feeling 100%
- vaccine now available
Hepatitis B
Transmitted through contact with blood or bodily fluids, sexual contact, punctures through skin, blood transfusions (tattoos, shared razors)
- much more hearty virus than HIV (infection rates for Hep B after needle stick injury as high as 30%, HIV 0.5%)
Hepatitis C
Prevalent in trauma population, prevalent in the IVDU population
- most common blood borne infection
- leading cause of liver transplant
- not efficiently transmitted through occupational exposure
- requires significant exposure for increased risk of infection - deep needle stick injury with visible blood
Hepatitis D
Also called “delta hepatitis”, a serious liver disease caused by infection with the Hepatitis D virus (HDV), person must first be infected with Hep B virus to develop Hep D, relatively uncommon
- no vaccine for hepatitis D, but it can be prevented in persons who are not already HBV infected by Hepatitis B vaccination
Hepatitis E
Usually results in an acute infection, it does not lead to a chronic infection, rare in US and Canada, common in many parts of the world
- transmission - ingestion of fecal matter, even in microscopic amounts, outbreaks are usually associated with contaminated water supply in countries with poor sanitation, no vaccine available
HIV
- at present there are no confirmed reports of pre-hospital workers acquiring HIV during job related activities
- transmitted through direct contact with contaminated body fluids (sexual contact, needles, mother to fetus)
- virus exists in blood and body fluids that contain blood
- risk of infection from other body fluids is not known - be on the safe side
- virus is not hearty and is killed easily once outside the body
Post exposure prophylaxis
- involves taking anti-HIV medication as soon as possible after exposure
- medications prevents replication of the virus
- must begin within 72 hours after exposure
- consists of 2-3 anti-retro viral medications taken for 28 days
Meningitis
Infection of the meninges surrounding the CNS, can be caused by bacteria or virus or other micro-organisms, contagiousness depends on the type of causative micro-organism, most outbreaks are a result of meningococcus bacteria
- transmission is by droplet spread or direct contact with nasopharyngeal secretions
- signs and symptoms - fever, severe headache, stiff neck, change in LOC, may have blotchy red or bluish rash, petichia (pinpoint round spots on the skin)
Tuberculosis
- chronic pulmonary disease acquired by inhalation of dried droplet nucleus containing a tubercle bacilli
- bacilli form necrotic cavities which cause chronic and debilitating lung disease
- transmitted primarily by coughing or sneezing
- signs and symptoms - cough, night sweats, weight loss, fatigue, hemoptysis
- early detection possible with tuberculin skin test
Tuberculin skin testing
The Mantoux tuberculin test (TST) is the standard method of determining whether a person is infected with Mycobacterium tuberculosis
- the TST is performed by injecting 0.1 mL of tuberculin purified protein derivative (PPD) into the inner surface of the forearm, the skin test reaction should be read 48 to 72 hours after administration
Tuberculin skin test results
Dependent on two factors
- measurement in millimetres of the induration
- person’s risk of being infected with TB and of progression to disease if infected
Influenza
- respiratory illness caused by a virus, droplet transmission (indirect contact), high mortality in geriatric population
- signs and symptoms - include fever, shakes, chills, headache, muscle pain, cough, runny nose
- key to prevention is annual flu shot - made based on anticipated strains
The most effective measure to protect yourself and others …
Is to wash your hands or use an alcohol based hand sanitizer
PPE for all calls
Nitrile gloves, safety glasses and surgical mask