Uncomplicated Pneumonia - CPS Statement Flashcards

1
Q

What is the most common bacterial cause of community-acquired pneumonia?

A

Streptococcus pneumoniae

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2
Q

Aside from S. pneumo, what are two other bacterial causes of pneumonia in school aged children?

A

Mycoplasma pneumoniae and Chlamydophila pneumoniae

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3
Q

How does Mycoplasma pneumoniae typically present?

A

M pneumoniae is typically characterized by malaise and headache for seven to 10 days before the onset of fever and cough, which then predominate.

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4
Q

As per the CPS statement, what are the two indications for drainage of pleural effusion?

A

Culture and drainage of a pleural effusion is indicated if the effusion is large and/or is clinically important as a cause for respiratory compromise or when response to medical therapy alone is not satisfactory.

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5
Q

What is the minimal acceptable blood volume for cultures in children/

A

the minimum volume of blood cultured should be at least:
- 1 mL to 2 mL in infants
- 4 mL to 5 mL in children <10 years of age
- 10 mL to 20 mL in older children

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6
Q

What are the potential indications for admission in a child with community acquired pneumonia?

A

Hospitalization is generally indicated if: - A child has inadequate oral intake
- Intolerant of oral therapy
- Has severe illness or respiratory compromise (eg, grunting, nasal flaring, apnea, hypoxemia)
- Pneumonia is complicated

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7
Q

What is the first line antibiotic management for uncomplicated community acquired pneumonia?

A

Ampicillin (IV) or amoxicillin (oral)

Provides good S. pneumo coverage

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8
Q

What is the benefit of ceftriaxone over ampicillin in children with septic shock or severe respiratory distress?

A

1) Offer better coverage than amoxicillin or ampicillin for beta-lactamase-producing H influenzae
2) May be more efficacious against high-level penicillin-resistant pneumococcus
3) Possibly provide empirical coverage for the rare methicillin-susceptible S aureus (a rare cause of pneumonia)

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9
Q

You have a child with community acquired pneumonia with a CXR that shows multilobar disease or pneumatoceles. What antibiotic should you add?

A

Vancomycin (in addition to CTX) to provide extra MRSA coverage

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10
Q

What antibiotic do you use to treat atypical pneumonia (i.e. mycoplasma or chlamydia)?

A

Macrolide antibiotic (azithromycin for five days or clarithromycin for 7 days)

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11
Q

You have a child with atypical pneumonia that you would like to treat with antibiotics, however they come from an area of Asia with high macrolide resistance. What is an alternative option?

A

Can also use doxcycline in children (in children age 8 or above)

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12
Q

If patients with suspected bacterial pneumonia do not respond to therapy within ___ h to ___ h, a chest radiograph should be obtained and a further clinical evaluation carried out

A

48 to 72 hrs

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13
Q

What is the duration of treatment for uncomplicated community-acquired pneumonia?

A

7 - 10 days

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14
Q

What is the duration of treatment for pneumonia complicated by abscess formation or empyema?

A

Usually 2 - 4 weeks

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15
Q

What is the recommend dose of amoxicillin for community acquired pneumonia?

A

40–90 mg/kg/day divided 3 times daily

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16
Q

What is the recommended dose of azithromycin for atypical community acquired pneumonia?

A

Given as a single daily dose; 10 mg/kg on day 1; 5 mg/kg on days 2 to 5; (5 days total)
Maximum 500 mg/day

17
Q

You have a 5 year old patient you want to treat for community-acquired pneumonia, however they have a penicillin allergy. What can you use instead?

A

It is now recognized that the cross-reactivity rate between penicillins and second- or third-generation cephalosporins (apart from cefoxitin) is extremely low.

Therefore, cefuroxime, cefprozil or ceftriaxone can be prescribed for penicillin-allergic patients

18
Q

Radiographic resolution in most uncomplicated pneumonia cases may take up to ____ to ____ weeks

A

4 to 6 weeks