Ultrafast Ultrasound Flashcards

1
Q

How does ultrafast ultrasound work?

A

All elements are used to transmit an unfocussed plane wave

The backscattered waves are measured by all the elements at once

An algorithm is used to form the image (all the A-lines simultaneously)

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2
Q

How does the conventional B-mode ultrasound imaging work?

A

An image consists of A-lines

For each A-line, a subset of the available transducer elements is used to generate a focussed transmit beam

A subset of the elements is used in receive mode to form an A-line

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3
Q

How can any field e.g. image, acoustic pressure map be constructed?

A

As a weighted sum of plane waves (has the form of a Fourier transform)

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4
Q

How can images be obtained with one incident plane wave?

A

1.Measure backscattered time series data on array

  1. Find the amplitudes of the constituent propagating plane waves of the backscattered field
  2. Relate these to the amplitudes of the constituent plane waves of the scattering distribution
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5
Q

What is an advantage of ultrafast ultrasound?

A

An image can be formed from one transmit pulse, so the image frame rate can be high

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6
Q

How is the round trip time found?

A

round trip time = 2 x depth / speed

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7
Q

How is the maximum frame rate found?

A

1 / round trip time

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8
Q

What are the disadvantages of ultrafast ultrasound?

A

There is no transmit focussing, so the backscattered signal amplitude is lower (and hence lower signal-to-noise ratio, SNR)

  • To ameliorate this, coherent angle-compounding is sometimes used (averaging unprocessed images from many plane wave transmit angles)
  • Incoherent angle compounding can still be used for speckle reduction
  • Any compounding reduces the frame rate
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9
Q

What needs to occur for a clear image to be produced using ultrafast ultrasound?

A

Multiple angles need to be used to produce clear image as features are less visible when single plane wave at one angle is used

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10
Q

How does ultrafast doppler work?

A

By sending a plane wave to acquire the full time samples for all image pixels simultaneously

The greyscale value is used to find doppler

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11
Q

What effect does ultrafast doppler have on power doppler?

A

Power Doppler information obtained at all pixels simultaneously at ~ 80 Hz (compared to 20 Hz with conventional systems)

Power doppler s-to-n ~ 50 x higher than conventional systems so finer details can be obtained

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12
Q

How does functional ultrasound work?

A

Relies on doppler images of the brain and the neurovascular coupling between blood flow and activated regions in brain (when neurons are activated with stimulus)

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13
Q

How does supersonic shear imaging work?

A

a sequential series of push pulses with an increasing focal depth is used to generate a single conical shear wave travelling across the entire field of view

Second, the field of view is imaged as the shear wave travels across it, deforming the tissue as it passes, and from these measurements the spatially-varying shear wave speed is determined and an image of the shear modulus is formed.

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14
Q

How are sequential push pulses used in supersonic shear imaging?

A

With focal regions of increasing depth along the same line

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15
Q

Where is the shear wave elasticity imaging (SWEI) time of flight assumptions valid?

A

Only over limited axial depth

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16
Q

How can we image the tissue as the shear wave passes through and thereby determine the shear wave speed everywhere?

A

To achieve 1 mm resolution requires 5000 frames per second (as shear wave travels at 5 m/s, so covers 1 mm in 0.2 ms)

17
Q

How is supersonic shear imaging used in breast?

A

reveals high stiffness: showing metastatic lymph node

reveals low stiffness:
showing an abscess

18
Q

How does ultrasound localisation microscopy work?

A

If we can image a single microbubble (point scatterer), we can know its position much more accurately than the image would suggest

By doing this very many times, an image can be built up that has much higher resolution than the imaging system could achieve alone

19
Q

What is the point spread function?

A

How the scatterer would appear in a conventional image

20
Q

What are the two approaches of imaging single microbubbles?

A

Approach (1): use low concentrations of microbubbles, so individual
microbubbles can be seen on the images

Approach (2): Image at high frame rate (500 fps) and use difference
imaging to image absence of microbubbles that have disintegrated

21
Q

Why is angle compounding needed in ultrafast ultrasound?

A

As there is no transmit beamforming so angle compounding is needed to improve signal to noise ratio

22
Q

What can ultrafast ultrasound (plane wave imaging) achieve?

A

Very high frame rates (several kHz)

23
Q

what is supersonic shear imaging and what does it give?

A

It is a type of elastography which gives quantitative images of shear wave speed