Ulcers

Question 1

Peptic Ulcer Disease

Answer 1

Chronic Disorder
*Most common cause of UGI bleed

Characterized by a break in the mucosa that comes in contact with pepsin and HCL

Types of Peptic Ulcers

1. Gastric Ulcers
2. Duodenal Ulcers

Question 2

Types of Peptic Ulcers

Answer 2

1. Gastric Ulcers

2. Duodenal Ulcers

Question 3

Gastric Ulcers

Answer 3

Found at the junction of the fundus and pylorus, but most on the less curvature of the antrum, a break in the mucosal barrier that extends into the muscularis mucosae.

Agents that break the mucosal barrier:

1. ASA
2. ETOH
3. NSAIDS
4. H. pylori

Question 4

Agents that break the mucosal barrier in Gastric Ulcers

Answer 4

1. ASA
2. ETOH
3. NSAIDs
4. H. Pylori

Question 5

Duodenal Ulcers

Answer 5

A chronic break in the duodenal mucosa extending through the muscularis mucosae that leaves scars

Most common type of peptic ulcer
assoc with increased acid secretion

90% of pts test positive for H. pylori infection

Question 6

Duodenal Ulcers is associated with

Answer 6

Increased acid secretion.

Acid secretion is stimulated by protein rich meals, calcium, and vagal stimulation

Question 7

The most common type of peptic ulcer

Answer 7

Duodenal Ulcer

Question 8

Stress Ulcers

Answer 8

Found in critically ill patients

Question 9

Stress Ulcers are caused by:

Answer 9

1. Acid hypersecretion
2. Gastric anoxia (hypoperfusion to stomach)
3. Altered mucosal defense mechanism
4. Decreased mucosal pH (becoming more acidic)

Question 10

Those at risk for stress ulcers

Answer 10

• Severe trauma
• Sepsis
• Severe burns
• Cranial or central nervous system dz
• Patients with long-term ventilatory support